The interplay between inflammatory cytokines and cardiometabolic disease: bi-directional mendelian randomisation study.

Autor: Karhunen V; Research Unit of Mathematical Sciences, University of Oulu, Oulu, Finland.; Research Unit of Population Health, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Gill D; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Huang J; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Singapore Institute for Clinical Sciences (SICS), Agency for Science Technology and Research (ASTAR), Singapore., Bouras E; Department of Hygiene and Epidemiology, Faculty of Medicine, University of Ioannina, Ioannina, Epirus, Greece., Malik R; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Faculty of Medicine, Munchen, Bayern, Germany., Ponsford MJ; Division of Immunology, Infection, and Inflammation, Tenovus Institute, Cardiff University, Cardiff, UK., Ahola-Olli A; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Papadopoulou A; Department of Hygiene and Epidemiology, Faculty of Medicine, University of Ioannina, Ioannina, Epirus, Greece., Palaniswamy S; Research Unit of Population Health, University of Oulu, Oulu, Finland., Sebert S; Research Unit of Population Health, University of Oulu, Oulu, Finland., Wielscher M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Auvinen J; Research Unit of Population Health, University of Oulu, Oulu, Finland., Veijola J; Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland., Herzig KH; Research Unit of Biomedicine, Medical Research Center (MRC), University of Oulu, University Hospital, Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Timonen M; Research Unit of Population Health, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Keinänen-Kiukaanniemi S; Research Unit of Population Health, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.; Healthcare and Social Services of Selänne, Pyhäjärvi, Finland., Dichgans M; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Faculty of Medicine, Munchen, Bayern, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany., Salmi M; MediCity and Institute of Biomedicine, University of Turku, Turku, Finland., Jalkanen S; MediCity and Institute of Biomedicine, University of Turku, Turku, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Salomaa V; Finnish Institute for Health and Welfare, Helsinki, Uusimaa, Finland., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland., Jones SA; Division of Immunology, Infection, and Inflammation, Tenovus Institute, Cardiff University, Cardiff, UK., Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Noord-Holland, Netherlands., Tsilidis KK; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, Faculty of Medicine, University of Ioannina, Ioannina, Epirus, Greece., Järvelin MR; Research Unit of Population Health, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK., Dehghan A; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; UK Dementia Research Institute, Imperial College London, London, UK.

Publikováno v: BMJ medicine [BMJ Med] 2023 Feb 14; Vol. 2 (1), pp. e000157. Date of Electronic Publication: 2023 Feb 14 (Print Publication: 2023).

Strategies to promote guideline adoption: lessons learned from the implementation of a national COVID-19 hospital guideline across NHS Wales.

Autor: Jefferies R; Public Health Wales, Cardiff, UK and Swansea University Medical School, Swansea, UK., Ponsford MJ; Immunodeficiency Centre for Wales, Cardiff, UK and Institute of Infection and Immunity, Cardiff, UK., Davies C; The Institute of Clinical Science and Technology, Cardiff, UK., Williams SJ; Swansea University School of Health and Social Care, Swansea, UK., Barry S; Public Health Wales, Cardiff, UK and University Hospital of Wales, Cardiff, UK.

Publikováno v: Future healthcare journal [Future Healthc J] 2022 Nov; Vol. 9 (3), pp. 262-267.

COVID-19 Vaccine Uptake and Efficacy in a National Immunodeficiency Cohort.

Autor: Ponsford MJ; Immunodeficiency Centre for Wales, University Hospital of Wales, Heath Park, Cardiff, UK.; Institute of Infection & Immunity, Henry Wellcome Building, School of Medicine, Cardiff University, Heath Park, Cardiff, UK., Evans K; Immunodeficiency Centre for Wales, University Hospital of Wales, Heath Park, Cardiff, UK., Carne EM; Immunodeficiency Centre for Wales, University Hospital of Wales, Heath Park, Cardiff, UK., Jolles S; Immunodeficiency Centre for Wales, University Hospital of Wales, Heath Park, Cardiff, UK. jollessr@cardiff.ac.uk.

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2022 May; Vol. 42 (4), pp. 728-731. Date of Electronic Publication: 2022 Feb 11.

Persistent COVID-19 Infection in Wiskott-Aldrich Syndrome Cleared Following Therapeutic Vaccination: a Case Report.

Autor: Bradley RE; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK., Ponsford MJ; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK.; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK., Scurr MJ; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK.; ImmunoServ LTD, Cardiff, UK., Godkin A; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Systems Immunity University Research Institute, School of Medicine, Cardiff University, Cardiff, UK.; Department of Gastroenterology & Hepatology, University Hospital of Wales, Cardiff, UK., Jolles S; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK. jollessr@cardiff.ac.uk.

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2022 Jan; Vol. 42 (1), pp. 32-35. Date of Electronic Publication: 2021 Oct 29.

Burden of nosocomial COVID-19 in Wales: results from a multicentre retrospective observational study of 2508 hospitalised adults.

Autor: Ponsford MJ; Immunodeficiency Centre for Wales, University of Wales Hospital, Cardiff, UK ponsfordm@cardiff.ac.uk.; Division Infection, Immunity, and Inflammation, School of Medicine, Cardiff University, Cardiff, UK., Jefferies R; Respiratory Health Implementation Group, NHS Wales Collaborative, Swansea, UK.; Swansea University Medical School, Institute of Life Science, Swansea University, Swansea, UK., Davies C; The Institute of Clinical Science and Technology, Cardiff, UK., Farewell D; Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK., Humphreys IR; Division Infection, Immunity, and Inflammation, School of Medicine, Cardiff University, Cardiff, UK.; Systems Immunity Research Institute, Cardiff University, Cardiff, UK., Jolles S; Immunodeficiency Centre for Wales, University of Wales Hospital, Cardiff, UK., Fairbairn S; Respiratory Health Implementation Group, NHS Wales Collaborative, Swansea, UK.; Department of Respiratory Medicine, Aneurin Bevan Health Board, Newport, UK., Lewis K; Department of Medicine, Prince Philip Hospital, Hywel Dda University Health Board, Carmarthen, UK.; College of Human and Health Sciences, Swansea University, Swansea, West Glamorgan, UK., Menzies D; Department of Respiratory Medicine, Betsi Cadwaladr University Health Board, Bangor, UK., Benjamin A; Department of Respiratory Medicine, Cwm Taf University Health Board, Abercynon, UK., Thaivalappil F; Department of Respiratory Medicine, Swansea Bay University Health Board, Port Talbot, UK., Williams C; Communicable Disease Surveillance Centre, Public Health Wales, Cardiff, UK., Barry SM; Department of Respiratory Medicine, Cardiff and Vale University Health Board, Cardiff, UK.

Publikováno v: Thorax [Thorax] 2021 Dec; Vol. 76 (12), pp. 1246-1249. Date of Electronic Publication: 2021 Jul 22.