COVID-19 and X-linked agammaglobulinemia (XLA) - insights from a monogenic antibody deficiency.

Autor: Ponsford MJ; Immunodeficiency Centre for Wales, University Hospital for Wales.; Henry Wellcome Building, Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff., Shillitoe BMJ; Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne., Humphreys IR; Henry Wellcome Building, Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff.; Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff., Gennery AR; Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Jolles S; Immunodeficiency Centre for Wales, University Hospital for Wales.

Publikováno v: Current opinion in allergy and clinical immunology [Curr Opin Allergy Clin Immunol] 2021 Dec 01; Vol. 21 (6), pp. 525-534.

The interplay between inflammatory cytokines and cardiometabolic disease: bi-directional mendelian randomisation study.

Autor: Karhunen V; Research Unit of Mathematical Sciences, University of Oulu, Oulu, Finland.; Research Unit of Population Health, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Gill D; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Huang J; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Singapore Institute for Clinical Sciences (SICS), Agency for Science Technology and Research (ASTAR), Singapore., Bouras E; Department of Hygiene and Epidemiology, Faculty of Medicine, University of Ioannina, Ioannina, Epirus, Greece., Malik R; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Faculty of Medicine, Munchen, Bayern, Germany., Ponsford MJ; Division of Immunology, Infection, and Inflammation, Tenovus Institute, Cardiff University, Cardiff, UK., Ahola-Olli A; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Papadopoulou A; Department of Hygiene and Epidemiology, Faculty of Medicine, University of Ioannina, Ioannina, Epirus, Greece., Palaniswamy S; Research Unit of Population Health, University of Oulu, Oulu, Finland., Sebert S; Research Unit of Population Health, University of Oulu, Oulu, Finland., Wielscher M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Auvinen J; Research Unit of Population Health, University of Oulu, Oulu, Finland., Veijola J; Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland., Herzig KH; Research Unit of Biomedicine, Medical Research Center (MRC), University of Oulu, University Hospital, Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Timonen M; Research Unit of Population Health, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Keinänen-Kiukaanniemi S; Research Unit of Population Health, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.; Healthcare and Social Services of Selänne, Pyhäjärvi, Finland., Dichgans M; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Faculty of Medicine, Munchen, Bayern, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany., Salmi M; MediCity and Institute of Biomedicine, University of Turku, Turku, Finland., Jalkanen S; MediCity and Institute of Biomedicine, University of Turku, Turku, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Salomaa V; Finnish Institute for Health and Welfare, Helsinki, Uusimaa, Finland., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland., Jones SA; Division of Immunology, Infection, and Inflammation, Tenovus Institute, Cardiff University, Cardiff, UK., Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Noord-Holland, Netherlands., Tsilidis KK; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, Faculty of Medicine, University of Ioannina, Ioannina, Epirus, Greece., Järvelin MR; Research Unit of Population Health, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK., Dehghan A; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; UK Dementia Research Institute, Imperial College London, London, UK.

Publikováno v: BMJ medicine [BMJ Med] 2023 Feb 14; Vol. 2 (1), pp. e000157. Date of Electronic Publication: 2023 Feb 14 (Print Publication: 2023).

An Analysis of Serological Response and Infection Outcomes Following Oxford-AstraZeneca (AZD1222) and Pfizer-BioNTech (mRNA BNT162b2) SARS-CoV-2 Vaccines in Kidney and Kidney-pancreas Transplants.

Autor: Asderakis A; Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom.; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom., Khalid U; Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom.; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom., Koimtzis G; Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom., Ponsford MJ; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, United Kingdom., Szabo L; Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom., Chalklin C; Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom., Bramhall K; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, United Kingdom., Grant L; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, United Kingdom., Moat SJ; Department of Medical Biochemistry, Immunology, and Toxicology, University Hospital of Wales, Cardiff, United Kingdom., Humphreys IR; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom., Jolles SR; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, United Kingdom.

Publikováno v: Transplantation [Transplantation] 2022 Jul 01; Vol. 106 (7), pp. 1421-1429. Date of Electronic Publication: 2022 Mar 08.

Persistent COVID-19 Infection in Wiskott-Aldrich Syndrome Cleared Following Therapeutic Vaccination: a Case Report.

Autor: Bradley RE; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK., Ponsford MJ; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK.; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK., Scurr MJ; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK.; ImmunoServ LTD, Cardiff, UK., Godkin A; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Systems Immunity University Research Institute, School of Medicine, Cardiff University, Cardiff, UK.; Department of Gastroenterology & Hepatology, University Hospital of Wales, Cardiff, UK., Jolles S; Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK. jollessr@cardiff.ac.uk.

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2022 Jan; Vol. 42 (1), pp. 32-35. Date of Electronic Publication: 2021 Oct 29.

A Systematic Review and Meta-Analysis of Inpatient Mortality Associated With Nosocomial and Community COVID-19 Exposes the Vulnerability of Immunosuppressed Adults.

Autor: Ponsford MJ; Immunodeficiency Centre for Wales, University Hospital for Wales, Cardiff, United Kingdom.; Henry Wellcome Building, Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom., Ward TJC; Department Respiratory Sciences, College of Life Sciences, University of Leicester, Leicester, United Kingdom.; Institute for Lung Health, National Institute for Health Research (NIHR) Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom., Stoneham SM; Department of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom.; Department of Microbiology and Infection, Royal Sussex County Hospital, Brighton, United Kingdom., Dallimore CM; Department of Anaesthetics, University Hospital for Wales, Cardiff, United Kingdom., Sham D; Department of Neonatology, University Hospitals of Leicester National Health Service (NHS) Trust, Leicestershire, United Kingdom., Osman K; Department of Respiratory Medicine, Cardiff and Vale University Health Board, Cardiff, United Kingdom., Barry SM; Department of Respiratory Medicine, Cardiff and Vale University Health Board, Cardiff, United Kingdom.; Respiratory Health Implementation Group, Swansea University, Swansea, United Kingdom., Jolles S; Immunodeficiency Centre for Wales, University Hospital for Wales, Cardiff, United Kingdom., Humphreys IR; Henry Wellcome Building, Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.; Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, United Kingdom., Farewell D; Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Oct 06; Vol. 12, pp. 744696. Date of Electronic Publication: 2021 Oct 06 (Print Publication: 2021).