Identification de facteurs génétiques impliqués dans les mécanismes d'autorégulation de la protéine TDP-43 dans la drosophile.

Autor: Pons, Marine

TDP-43 est une protéine de liaison aux acides nucléiques qui joue un rôle essentiel dans le métabolisme de l'ARN. À l'état physiologique, un contrôle strict des niveaux d’expression de cette protéine est critique pour la fonction et la surv

Externí odkaz: http://www.theses.fr/2018NORMR040

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Intracellular Positioning Systems Limit the Entropic Eviction of Secondary Replicons Toward the Nucleoid Edges in Bacterial Cells

Autor: Dauverd -Girault, Julie, Planchenault, Charlène, Pons, Marine, Schiavon, Caroline, Siguier, Patricia, Rech, Jérôme, Guynet, Catherine, Dauverd-Girault, Julie, Cury, Jean, Rocha, Eduardo, Junier, Ivan, Cornet, François, Espéli, Olivier

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, 2020, 432 (3), pp.745-761. ⟨10.1016/j.jmb.2019.11.027⟩
Journal of Molecular Biology, Elsevier, 2020, 432 (3), pp.745-761. ⟨10.1016/j.jmb.2019.11.027⟩

International audience; Bacterial genomes, organized intracellularly as nucleoids, are composed of a main chromosome coexisting with different types of secondary replicons. Secondary replicons are major drivers of 16 bacterial adaptation by gene exch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d657b69eea0eea0162f1d676d112c747
https://doi.org/10.1016/j.jmb.2019.11.027

Additional file 2 of The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias

Autor: Chen, Yongping, Krishnan, Gopinath, Parsi, Sepideh, Pons, Marine, Nikolaki, Veroniki, Cao, Lu, Xu, Zuoshang, Gao, Fen-Biao

Additional file 2: Fig. S2. Immunocytochemical analysis of the interaction between CHMP2B and EGFP-Spastin in HeLa cells. Flag-CHMP2BIntron5 bound more EGFP-Spastin than Flag-CHMP2BWT. Scale bar, 10 μm.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380b3aab2f468cf8280831e9be999206

Additional file 3 of The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias

Autor: Chen, Yongping, Krishnan, Gopinath, Parsi, Sepideh, Pons, Marine, Nikolaki, Veroniki, Cao, Lu, Xu, Zuoshang, Gao, Fen-Biao

Additional file 3: Fig. S3. Effect of CHMP2BIntron5 on the SPAST mRNA level in HEK293 cells in three independent experiments. ***p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25743f4679c4adcb19eba778f2e95ec