Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ponnandy Prabhu"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14622 (2023)
Virus-like particles (VLPs) have been proposed as an attractive tool in SARS-CoV-2 vaccine development, both as (1) a vaccine candidate with high immunogenicity and low reactogenicity and (2) a substitute for live virus in functional and neutralizati
Externí odkaz:
https://doaj.org/article/d3a790cf83c4435fbe7cd36326bb69d3
Publikováno v:
Energies, Vol 15, Iss 12, p 4242 (2022)
Acetoin, a four-carbon hydroxyl-keto compound, is used in the food, pharmaceutical, and chemical industries. The cascade enzymatic production is considered a promising and efficient method to produce acetoin. However, the stability and compatibility
Externí odkaz:
https://doaj.org/article/1eaf08223a904cba8638251633e39541
Publikováno v:
ACS Synthetic Biology. 9:2119-2131
The complexities of pathway engineering necessitate screening libraries to discover phenotypes of interest. However, this approach is challenging when desirable phenotypes cannot be directly linked to growth advantages or fluorescence. In these cases
Autor:
Hui Gao, Deepika Mutukuri, Luke F. Bugada, Fei Wen, Jung-Kul Lee, Lester W. Lee, Robert M. Ziff, Christine M. Yee, Cori Roth, Mason R. Smith, Ponnandy Prabhu
Publikováno v:
Nature catalysis
Cooperative enzyme catalysis in nature has long inspired the application of engineered multi-enzyme assemblies for industrial biocatalysis. Despite considerable interest, efforts to harness the activity of cell-surface displayed multi-enzyme assembli
Autor:
Moshe Kotler, Orit Amsalem, Dinorah Barasch, Ponnandy Prabhu, Taher Nassar, Natalya Naraykin, Simon Benita, Ayala Rohald
Publikováno v:
Journal of Drug Targeting. 27:590-600
Lopinavir (LPV), an efficient drug for HIV infection treatment, was incorporated into biodegradable PLGA nanocapsules (NCs) embedded in microparticles (MCPs) using the spray-drying technique in an attempt to bypass the P-gp efflux and protect the dru
Publikováno v:
ACS synthetic biology. 9(8)
The complexities of pathway engineering necessitate screening libraries to discover phenotypes of interest. However, this approach is challenging when desirable phenotypes cannot be directly linked to growth advantages or fluorescence. In these cases
Publikováno v:
Journal of Molecular Biology. 426:2840-2853
Deamination of cytidine residues in viral DNA is a major mechanism by which APOBEC3G (A3G) inhibits vif-deficient human immunodeficiency virus type 1 (HIV-1) replication. dC-to-dU transition following RNase-H activity leads to viral cDNA degradation,
Publikováno v:
Applied Microbiology and Biotechnology. 89:635-644
Whole-genome sequence analysis of Bacillus halodurans ATCC BAA-125 revealed an isomerase gene (rhaA) encoding an l-rhamnose isomerase (l-RhI). The identified l -RhI gene was cloned from B. halodurans and over-expressed in Escherichia coli. DNA sequen
Publikováno v:
Applied and Environmental Microbiology. 76:1653-1660
Bacillus licheniformis l -arabinose isomerase ( l -AI) is distinguished from other l -AIs by its high degree of substrate specificity for l -arabinose and its high turnover rate. A systematic strategy that included a sequence alignment-based first sc
Autor:
Jin-Ha Kim, Ponnandy Prabhu, Hee-Jung Moon, Marimuthu Jeya, Manish Kumar Tiwari, Jung-Kul Lee, Raushan Kumar Singh
Publikováno v:
Applied Microbiology and Biotechnology. 85:1839-1847
An isolated gene from Bacillus subtilis str. 168 encoding a putative isomerase was proposed as an L-arabinose isomerase (L-AI), cloned into Escherichia coli, and its nucleotide sequence was determined. DNA sequence analysis revealed an open reading f