Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ponmathi Panneerpandian"'
Publikováno v:
Medical Oncology. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00bf0ce5be81967ff2a79d7ecadc60de
https://doi.org/10.1007/s12032-023-01984-0
https://doi.org/10.1007/s12032-023-01984-0
Publikováno v:
J Cell Commun Signal
Gastric cancer is one of the leading causes of cancer-related death worldwide. The transcription factor YY1 regulates diverse biological processes, including cell proliferation, development, DNA damage responses, and carcinogenesis. This study was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f39cb68b9eef3f3a67fa3caab419393
https://doi.org/10.1007/s12079-021-00608-4
https://doi.org/10.1007/s12079-021-00608-4
Publikováno v:
Human Cell. 34:445-456
To overcome the issues of poor prognosis and to tackle the non-responsiveness to various chemotherapeutics; it is necessary to develop targeted cancer therapeutic agents. Also, it is being necessary to understand the molecular targets of the drug can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3dc21b3a800de9cecb6627571bbe04
https://doi.org/10.1007/s13577-020-00476-x
https://doi.org/10.1007/s13577-020-00476-x
Autor:
Jaishree Pandian, Madhusudhanan Gnanasekaran, Vikash Vittal, Balaji T Sekar, Helen D Jemimah, Ponmathi Panneerpandian, Satyajit Patwardhan, Indhu Kannan, Prem Suresh, Karthikeyan Selvarasu, Mohan Narasimhan, Ramesh Ardhanari, Kumaresan Ganesan
Gastric cancer is the third most common cause of cancer-related mortality. Genome-wide studies pave way for the delineation of heterogeneities and the possible genomics-guided stratification of tumors. Numerous whole-genome profiles have been establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60a6f57b7d1c2b1cada01519a0e730a9
https://doi.org/10.21203/rs.3.rs-1476204/v1
https://doi.org/10.21203/rs.3.rs-1476204/v1
Autor:
Helen Jemimah Devanandan, Karthikeyan Muthupandi, Jaishree Pandian, Karthik Balakrishnan, Ponmathi Panneerpandian, Karthikeyan Selvarasu, Kumaresan Ganesan, Balaji T. Sekar
Publikováno v:
Annals of the New York Academy of Sciences. 1467:94-111
The identification of new drugs for the targeted therapy of gastric cancer remains an important need. The RAS/RAF/MEK/ERK/ELK1 signaling cascade is activated in many cancers, including gastric cancer. To identify the targetable inhibitors of the ERK/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4037c5dc33cab955252616665436646
https://doi.org/10.1111/nyas.14288
https://doi.org/10.1111/nyas.14288
Autor:
Jaishree Pandian, Ponmathi Panneerpandian, Balaji T. Sekar, Karthikeyan Selvarasu, Kumaresan Ganesan
Publikováno v:
Functionalintegrative genomics. 22(6)
Deregulated transcription programs and signaling pathways are the critical factors involved in the process of carcinogenesis. Signaling pathway-based classification of tumors is expected to pave the way for the development of targeted therapeutics. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc3b3e891e7b248e5e4bf339b426183
https://pubmed.ncbi.nlm.nih.gov/35987846
https://pubmed.ncbi.nlm.nih.gov/35987846
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 74
Elevated expression of YY1 is known to confer anti-apoptotic phenotype and hence is an attractive target for cancer therapeutics. In a repurpose screening, towards the identification of the inhibitors of YY1 regulated transcription in gastric cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613810903a05ba5914be588fe34a628d
https://pubmed.ncbi.nlm.nih.gov/33771646
https://pubmed.ncbi.nlm.nih.gov/33771646
Publikováno v:
Cancer Immunology, Immunotherapy. 66:941-954
The existing large number of gene expression profiles of tumour samples offers a great advantage for the integrative functional genomic exploration of molecular dysregulation in cancers. The clusters of genes (modules) derived from a gastric cancer (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22945479b39af730d4e6ed2ba5c0dbe0
https://doi.org/10.1007/s00262-017-1998-7
https://doi.org/10.1007/s00262-017-1998-7
Autor:
C. Karthikeyan, Kumaresan Ganesan, Anantharaj Marimuthu, Ponmathi Panneerpandian, Helen Jemimah Devanandan
Publikováno v:
Antiviral research. 174
Yin Yang 1 (YY1) is a ubiquitous transcription factor with both transcriptional activating and repressing functions. Targeting YY1 is considered as a potential therapeutic strategy for several malignancies. Telomerase Reverse Transcriptase (TERT) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a69e56bd1c0df030b24342b0f23f67
https://pubmed.ncbi.nlm.nih.gov/31846633
https://pubmed.ncbi.nlm.nih.gov/31846633
Autor:
Suresh K. Rayala, Karthik Balakrishnan, Helen Jemimah Devanandan, Balaji T. Sekar, Kumaresan Ganesan, Ponmathi Panneerpandian
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35688cde278ee8032cdb972076cfe789
https://pubmed.ncbi.nlm.nih.gov/31279909
https://pubmed.ncbi.nlm.nih.gov/31279909