Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Pongsakorn Thawornpan"'
Autor:
Tipanan Khunsri, Pongsakorn Thawornpan, Pachara Tianpothong, Thanitta Suangtamai, Pintip Ngamjanyaporn, Chaniya Leepiyasakulchai, Kittikorn Wangriatisak, Prapaporn Pisitkun, Patchanee Chootong
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Systemic lupus erythematosus (SLE) is the quintessential autoimmune disease, as it is characterized by hyperactivity of CD4+ T cells and subsequently drives lupus pathology. Follicular helper T (TFH) cells play an important role i
Externí odkaz:
https://doaj.org/article/85226088e98b420487aab866d40c4bb5
Autor:
Pongsakorn Thawornpan, Zulfa Zahra Salsabila, Piyawan Kochayoo, Tipanan Khunsri, Chayapat Malee, Kittikorn Wangriatisak, Chaniya Leepiyasakulchai, Francis Babila Ntumngia, John H Adams, Patchanee Chootong
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 10, p e0012625 (2024)
BackgroundPlasmodium vivax is the dominant Plasmodium spp. causing malaria throughout tropical and sub-tropical countries. Humoral immunity is induced during P. vivax infection. However, data on longevity of antibody and memory B cell (MBC) responses
Externí odkaz:
https://doaj.org/article/63f22c5cc8ba4e96a36c2d9e0b408915
Autor:
Francis Babila Ntumngia, Surendra Kumar Kolli, Pradeep Annamalai Subramani, Samantha J. Barnes, Justin Nicholas, Madison M. Ogbondah, Brian B. Barnes, Nichole D. Salinas, Pongsakorn Thawornpan, Niraj H. Tolia, Patchanee Chootong, John H. Adams
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In Plasmodium vivax, the most studied vaccine antigens are aimed at blocking merozoite invasion of erythrocytes and disease development. Very few studies have evaluated pre-erythrocytic (PE) stage antigens. The P. vivax circumsporozoite prot
Externí odkaz:
https://doaj.org/article/d14402fce10d475e9b4b167329817cb1
Autor:
Pongsakorn Thawornpan, Justin Nicholas, Chayapat Malee, Piyawan Kochayoo, Kittikorn Wangriatisak, Pachara Tianpothong, Francis Babila Ntumngia, Samantha J Barnes, John H Adams, Patchanee Chootong
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011907 (2024)
BackgroundP. vivax malaria is a major global health burden hindering social and economic development throughout many tropical and sub-tropical countries. Pre-erythrocytic (PE) vaccines emerge as an attractive approach for the control and elimination
Externí odkaz:
https://doaj.org/article/edfec4a9ede647b7a2ac5009c59cdb72
Autor:
Pongsakorn Thawornpan, Chayapat Malee, Piyawan Kochayoo, Kittikorn Wangriatisak, Chaniya Leepiyasakulchai, Francis B. Ntumngia, Sai Lata De, John H. Adams, Patchanee Chootong
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Plasmodium vivax Duffy Binding Protein region II (PvDBPII) is a leading vaccine candidate against blood-stage vivax malaria. Anti-PvDBPII antibodies potentially block parasite invasion by inhibition of erythrocyte binding. However, knowledge
Externí odkaz:
https://doaj.org/article/5fb7b50a80ce45fbb6b781a5de8698fd
Autor:
Justin Nicholas, Sai Lata De, Pongsakorn Thawornpan, Awtum M Brashear, Surendra Kumar Kolli, Pradeep Annamalai Subramani, Samantha J Barnes, Liwang Cui, Patchanee Chootong, Francis Babila Ntumngia, John H Adams
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011598 (2023)
Plasmodium vivax pre-erythrocytic (PE) vaccine research has lagged far behind efforts to develop Plasmodium falciparum vaccines. There is a critical gap in our knowledge of PE antigen targets that can induce functionally inhibitory neutralizing antib
Externí odkaz:
https://doaj.org/article/08bbc6fea1f74b929c247c9d79da502b
Autor:
Piyawan Kochayoo, Pongsakorn Thawornpan, Kittikorn Wangriatisak, Siriruk Changrob, Chaniya Leepiyasakulchai, Ladawan Khowawisetsut, John H. Adams, Patchanee Chootong
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract For development of a long-lasting protective malaria vaccine, it is crucial to understand whether Plasmodium-induced memory B cells (MBCs) or plasma cells develop and stably contribute to protective immunity, or on the contrary the parasite
Externí odkaz:
https://doaj.org/article/9edb84c2227542c6b841090a2af7803c
Autor:
Piyawan Kochayoo, Pattarawan Sanguansuttikul, Pongsakorn Thawornpan, Kittikorn Wangriatisak, John H. Adams, Francis B. Ntumngia, Patchanee Chootong
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-11 (2021)
Abstract Background Development of an effective vaccine against blood-stage malaria requires the induction of long-term immune responses. Plasmodium vivax Reticulocyte Binding Protein 1a (PvRBP1a) is a blood-stage parasite antigen which is associated
Externí odkaz:
https://doaj.org/article/1c37108c30b842d6adca5a1d29dda6d1
CD4+ T-cell cooperation promoted pathogenic function of activated naïve B cells of patients with SLE
Autor:
Prapaporn Pisitkun, Pintip Ngamjanyaporn, Kittikorn Wangriatisak, Piyawan Kochayoo, Pongsakorn Thawornpan, Chaniya Leepiyasakulchai, Thanitta Suangtamai, Ladawan Khowawisetsut, Prasong Khaenam, Patchanee Chootong
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Objective To explore cooperation between activated naïve (aNAV) B cells and CD4+ T cells in the pathogenesis of SLE through autoantibody production, T-cell differentiation and inflammatory cytokine secretion.Methods Peripheral blood mononuclear cell
Externí odkaz:
https://doaj.org/article/8f3446dda3f948a488151f065f9eabc0
Autor:
Pongsakorn Thawornpan, Siriruk Changrob, Piyawan Kochayoo, Kittikorn Wangriatisak, Francis B. Ntumngia, Sai Lata De, Eun-Taek Han, John H. Adams, Patchanee Chootong
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Duffy binding protein region II (DBPII) is considered a strong potential vaccine candidate of blood-stage P. vivax. However, the highly polymorphic nature of this protein often misdirects immune responses, leading them to be strain-specific. Details
Externí odkaz:
https://doaj.org/article/54c352cc92ca4929b6cf6c0c20da53b2