Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Ponciano D, Cruz"'
Publikováno v:
JID Innovations, Vol 2, Iss 1, Pp 100061- (2022)
Physician‒scientists have made countless discoveries, and their dwindling numbers are a significant concern. Although dermatology has become an increasingly popular destination for physician‒scientist trainees, the proportion of trainees who purs
Externí odkaz:
https://doaj.org/article/39ec0f50ea00410ca3a645e69438c708
Autor:
Khang D. Nguyen, MD, Tyler Enos, MD, Travis Vandergriff, MD, Rebecca Vasquez, MD, Ponciano D. Cruz, MD, Heidi T. Jacobe, MD, Melissa M. Mauskar, MD
Publikováno v:
JAAD International, Vol 1, Iss 1, Pp 21-22 (2020)
Externí odkaz:
https://doaj.org/article/e39176f222c640c4a0ac16f1beae5492
Autor:
Kiyoshi Ariizumi, David E. Gerber, Ponciano D. Cruz, Song Zhang, Vinita Popat, Farjana Fattah, Masato Kobayashi, Vijay Ramani, Jin-Sung Chung
Purpose:Immune checkpoint inhibitors (ICI) benefit only a minority of treated patients with cancer. Identification of biomarkers distinguishing responders and nonresponders will improve management of patients with cancer. Because the DC-HIL checkpoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38546e48983f3c1cd27a973d7b425391
https://doi.org/10.1158/1078-0432.c.6529857.v1
https://doi.org/10.1158/1078-0432.c.6529857.v1
Autor:
Kiyoshi Ariizumi, Ponciano D. Cruz, Farshid Araghizadeh, Purva Gopal, David Harker, Vijay Ramani, Yutaka Horiuchi, Saad Khan, Barbara Haley, John Mansour, Kevin Courtney, Udit Verma, Yull Arriaga, Muhammad Beg, Jin-Sung Chung, Masato Kobayashi
Purpose:Blocking the function of myeloid-derived suppressor cells (MDSC) is an attractive approach for cancer immunotherapy. Having shown DC-HIL/GPNMB to be the T-cell-inhibitory receptor mediating the suppressor function of MDSCs, we evaluated the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19d88cbcbdf4ea0cc8c51d1ffabb4c6
https://doi.org/10.1158/1078-0432.c.6528878
https://doi.org/10.1158/1078-0432.c.6528878
Autor:
Kiyoshi Ariizumi, Ponciano D. Cruz, Farshid Araghizadeh, Purva Gopal, David Harker, Vijay Ramani, Yutaka Horiuchi, Saad Khan, Barbara Haley, John Mansour, Kevin Courtney, Udit Verma, Yull Arriaga, Muhammad Beg, Jin-Sung Chung, Masato Kobayashi
Supplementary Table S1. Summary of MDSC analysis of metastatic cancer patents. aAll cancer patients are diagnosed as stage III or IV. Supplementary Table S2. Correlation of variables and expansion of DC-HIL+ MDSCs among colorectal cancer patients. Su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e114b85cf73327c71d043236f1a78d
https://doi.org/10.1158/1078-0432.22474691
https://doi.org/10.1158/1078-0432.22474691
Autor:
Kiyoshi Ariizumi, Ponciano D. Cruz, Farshid Araghizadeh, Purva Gopal, David Harker, Vijay Ramani, Yutaka Horiuchi, Saad Khan, Barbara Haley, John Mansour, Kevin Courtney, Udit Verma, Yull Arriaga, Muhammad Beg, Jin-Sung Chung, Masato Kobayashi
Supplementary Fig. S1. Early stages CRC patients expressed very low DC-HIL expression on MDSCs. Supplementary Fig. S2. No effect of anti-CD14 mAb on T cell suppressor function of MDSCs. Supplementary Fig. S3. DC-HILneg MC38 and CT26 mouse colon cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91b38e14ffea18c2a07db0de34ada8a
https://doi.org/10.1158/1078-0432.22474694
https://doi.org/10.1158/1078-0432.22474694
Autor:
Kiyoshi Ariizumi, David E. Gerber, Ponciano D. Cruz, Song Zhang, Vinita Popat, Farjana Fattah, Masato Kobayashi, Vijay Ramani, Jin-Sung Chung
Figure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Figure S7, Figure S8, Table S1, Table S2, Table S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b4b5019c8a1eacc0fa4c9bbcd032b4
https://doi.org/10.1158/1078-0432.22478124
https://doi.org/10.1158/1078-0432.22478124
Supplementary Figure 1 from DC-HIL/Glycoprotein Nmb Promotes Growth of Melanoma in Mice by Inhibiting the Activation of Tumor-Reactive T Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc88de41dc9c607d02f10c0c89c0d9a
https://doi.org/10.1158/0008-5472.22382076.v1
https://doi.org/10.1158/0008-5472.22382076.v1
DC-HIL/glycoprotein nmb (Gpnmb) expressed on antigen-presenting cells attenuates T-cell activation by binding to syndecan-4 (SD-4) on activated T cells. Because DC-HIL/Gpnmb is expressed abundantly by mouse and human melanoma lines, we posited that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed8fd42d3c4b594d7fc49de7a90de4e1
https://doi.org/10.1158/0008-5472.c.6500091.v1
https://doi.org/10.1158/0008-5472.c.6500091.v1
Supplementary Figure 4 from DC-HIL/Glycoprotein Nmb Promotes Growth of Melanoma in Mice by Inhibiting the Activation of Tumor-Reactive T Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8e82e1335937982fda1a281c844848
https://doi.org/10.1158/0008-5472.22382067.v1
https://doi.org/10.1158/0008-5472.22382067.v1