Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Polysaccharides -- genetics"'
Autor:
Yao Meng, Sami Sanlidag, Sacha A. Jensen, Sean A. Burnap, Weston B. Struwe, Andreas H. Larsen, Xinyi Feng, Shruti Mittal, Mark S. P. Sansom, Cecilia Sahlgren, Penny A. Handford
Publikováno v:
Science Signaling, 15(755):eabo3507. American Association for the Advancement of Science (AAAS)
Meng, Y, Sanlidag, S, Jensen, S A, Burnap, S A, Struwe, W B, Larsen, A H, Feng, X, Mittal, S, Sansom, M S P, Sahlgren, C & Handford, P A 2022, ' An N-glycan on the C2 domain of JAGGED1 is important for Notch activation ', Science Signaling, vol. 15, no. 755, eabo3507 . https://doi.org/10.1126/scisignal.abo3507
Meng, Y, Sanlidag, S, Jensen, S A, Burnap, S A, Struwe, W B, Larsen, A H, Feng, X, Mittal, S, Sansom, M S P, Sahlgren, C & Handford, P A 2022, ' An N-glycan on the C2 domain of JAGGED1 is important for Notch activation ', Science Signaling, vol. 15, no. 755, eabo3507 . https://doi.org/10.1126/scisignal.abo3507
The canonical members of the Jagged/Serrate and Delta families of transmembrane ligands have an extracellular, amino-terminal C2 domain that binds to phospholipids and is required for optimal activation of the Notch receptor. Somatic mutations that c
Autor:
Andriana Konstantinidi, Rebecca Nason, Tomislav Čaval, Lingbo Sun, Daniel M. Sørensen, Sanae Furukawa, Zilu Ye, Renaud Vincentelli, Yoshiki Narimatsu, Sergey Y. Vakhrushev, Henrik Clausen
Publikováno v:
Konstantinidi, A, Nason, R, Čaval, T, Sun, L, Sørensen, D M, Furukawa, S, Ye, Z, Vincentelli, R, Narimatsu, Y, Vakhrushev, S Y & Clausen, H 2022, ' Exploring the glycosylation of mucins by use of O-glycodomain reporters recombinantly expressed in glycoengineered HEK293 cells ', Journal of Biological Chemistry, vol. 298, no. 4, 101784 . https://doi.org/10.1016/j.jbc.2022.101784
Mucins and glycoproteins with mucin-like regions contain densely O-glycosylated domains often found in tandem repeat (TR) sequences. These O-glycodomains have traditionally been difficult to characterize because of their resistance to proteolytic dig
Autor:
Paul M. Sullam, Tina M. Iverson, Barbara A. Bensing, Leo Alexander Dworkin, Henrik Clausen, Daniel Madriz Sørensen, Ajit Varki, Sanae Furukawa, Cornelis A. M. de Haan, Fabien Durbesson, Lars Hansen, Rebecca Nason, Yoshiki Narimatsu, Leonor David, Bernard Henrissat, Sergey Y. Vakhrushev, Zilu Ye, Ulla Mandel, Andriana Konstantinidi, Hiren J. Joshi, Adnan Halim, Renaud Vincentelli, Erik de Vries, Christian Büll, Lingbo Sun, Wenjuan Du
Publikováno v:
Nason, R, Büll, C, Konstantinidi, A, Sun, L, Ye, Z, Halim, A, Du, W, Sørensen, D M, Durbesson, F, Furukawa, S, Mandel, U, Joshi, H J, Dworkin, L A, Hansen, L, David, L, Iverson, T M, Bensing, B A, Sullam, P M, Varki, A, Vries, E D, de Haan, C A M, Vincentelli, R, Henrissat, B, Vakhrushev, S Y, Clausen, H & Narimatsu, Y 2021, ' Display of the human mucinome with defined O-glycans by gene engineered cells ', Nature Communications, vol. 12, no. 1, 4070 . https://doi.org/10.1038/s41467-021-24366-4
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications, 12(1), 1. Nature Publishing Group
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications, 12(1), 1. Nature Publishing Group
Nature communications, vol 12, iss 1
Mucins are a large family of heavily O-glycosylated proteins that cover all mucosal surfaces and constitute the major macromolecules in most body fluids. Mucins are primarily defined by their variable tandem repeat (TR) domains that are densely decor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9170cabfd047173f87ff4fd273eae5bf
https://curis.ku.dk/ws/files/275944012/s41467_021_24366_4.pdf
https://curis.ku.dk/ws/files/275944012/s41467_021_24366_4.pdf
Autor:
Andreia Almeida, Catarina Gomes, Barbara Adamczyk, Lylia Drici, Chunsheng Jin, Luís Pedro Afonso, Niclas G. Karlsson, Martin R. Larsen, Lúcio Lara Santos, María Ibáñez-Vea, Celso A. Reis, Ana Magalhães, Stefan Mereiter, Daniel Kolarich, José Alexandre Ferreira
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Mereiter, S, Magalhães, A, Adamczyk, B, Jin, C, Almeida, A, Drici, L, Ibáñez-Vea, M, Gomes, C, Ferreira, J A, Afonso, L P, Santos, L L, Larsen, M R, Kolarich, D, Karlsson, N G & Reis, C A 2016, ' Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer ', BBA Reviews on Cancer, vol. 1860, no. 8, pp. 1795-1808 . https://doi.org/10.1016/j.bbagen.2015.12.016
Biochimica et Biophysica Acta (BBA)-General Subjects
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Mereiter, S, Magalhães, A, Adamczyk, B, Jin, C, Almeida, A, Drici, L, Ibáñez-Vea, M, Gomes, C, Ferreira, J A, Afonso, L P, Santos, L L, Larsen, M R, Kolarich, D, Karlsson, N G & Reis, C A 2016, ' Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer ', BBA Reviews on Cancer, vol. 1860, no. 8, pp. 1795-1808 . https://doi.org/10.1016/j.bbagen.2015.12.016
Biochimica et Biophysica Acta (BBA)-General Subjects
Background Terminal a2-3 and a2-6 sialylation of glycans precludes further chain elongation, leading to the biosynthesis of cancer relevant epitopes such as sialyl-Lewis X (SLe X ). SLe X overexpression is associated with tumor aggressive phenotype a
Autor:
Van Antwerpen, Pierre, Slomianny, Marie-Christine, Zouaoui Boudjeltia, Karim, Delporte, Cédric, Faid, Valegh, Calay, Damien, Rousseau, Alexandre, Moguilevsky, Nicole, Raes, Martine, Vanhamme, Luc, Furtmüller, Paul G, Obinger, Christian, Vanhaeverbeek, Michel, Neve, Jean, Michalski, Jean-Claude
Publikováno v:
The Journal of biological chemistry, 285 (21
The involvement of myeloperoxidase (MPO) in various inflammatory conditions has been the scope of many recent studies. Besides its well studied catalytic activity, the role of its overall structure and glycosylation pattern in biological function is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2101::83f631213656f590e7380d68e3058440
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/67963
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/67963