Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Polyphen"'
Autor:
Howeida Abdullah Mustafa, Afraa Mohamed Suliman Albkrye, Buthiena Mohamed AbdAlla, Mona AbdelRahman Mohammed Khair, Nidal Abdelwahid, Hind Abdelaziz Elnasri
Publikováno v:
Clinical and Translational Medicine, Vol 9, Iss 1, Pp 1-10 (2020)
Abstract Background The Peroxisome proliferator-activated receptor gamma gene (PPARG), encodes a member of the peroxisome-activated receptor subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) which regulate trans
Externí odkaz:
https://doaj.org/article/c7ff518da29242a0b7b6c008cd77784e
Akademický článek
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Autor:
Saleh Abdullah Aloyuni
Publikováno v:
Journal of King Saud University: Science, Vol 33, Iss 6, Pp 101514- (2021)
Objective: The Aldo-keto reductase family consists of a number of enzymes which are essential to the catalysis of redox transformation and which are also involved in intermediate metabolism and detoxification. Several studies have been reported that
Externí odkaz:
https://doaj.org/article/6da4bd61ce1d479aba18c7e6c9f14846
Akademický článek
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Publikováno v:
Biological Research, Vol 48, Iss 0, Pp 1-8 (2015)
The current state of the art in medical genetics is to identify and classify the functional (deleterious) or non-functional (neutral) single amino acid substitutions (SAPs), also known as non-synonymous SNPs (nsSNPs). The primary goal is to elucidate
Externí odkaz:
https://doaj.org/article/78d2c919cbb54d3cab7bd72ea09122c6
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6400-6416 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Highlights • Prediction of mutations in transmembrane proteins is of significance for diseases diagnosis. • Building on the evolutionary information, proposed the Gaussian WAPSSM algorithm. • Based on WAPSSM and sequence
Highlights • Prediction of mutations in transmembrane proteins is of significance for diseases diagnosis. • Building on the evolutionary information, proposed the Gaussian WAPSSM algorithm. • Based on WAPSSM and sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab4583865fc088881c6f516bb043a13
http://www.sciencedirect.com/science/article/pii/S200103702100489X
http://www.sciencedirect.com/science/article/pii/S200103702100489X
Autor:
Olivares Adell, Clara
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
[ES] Los viroides son pequeñas entidades fitopatógenas constituidas por RNA circular monocatenario que únicamente consta de entre 250-400 nucleótidos, carecen de capacidad codificante y causan síntomas similares a los inducidos por virus. Los vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6bcfdfffbe813d704bfb79a3f6a4aeeb
https://hdl.handle.net/10251/173637
https://hdl.handle.net/10251/173637
Publikováno v:
Human Genomics, Vol 2, Iss 5, Pp 287-296 (2006)
Abstract Although highly penetrant alleles of BRCA1 and BRCA2 have been shown to predispose to breast cancer, the majority of breast cancer cases are assumed to result from the presence of low-moderate penetrant alleles and environmental carcinogens.
Externí odkaz:
https://doaj.org/article/4c5519817adf46eda5ebea61b7cab8f9
Autor:
Vita Rozman, Tanja Kunej
Publikováno v:
Omics. a ǂjournal of integrative biology, vol. 22, no. 6, pp. 410-421, 2018.
Harnessing the genomics big data requires innovation in how we extract and interpret biologically relevant variants. Currently, there is no established catalog of prioritized missense variants associated with deleterious protein function phenotypes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242339b152cc0b6818b1bd43585a151d
https://doi.org/10.1089/omi.2018.0046
https://doi.org/10.1089/omi.2018.0046
Autor:
Hind Abdelaziz Elnasri, Howeida Abdullah Mustafa, Mona AbdelRahman Mohammed Khair, Nidal Abdelwahid, Afraa Mohamed Suliman Albkrye, Buthiena Mohamed AbdAlla
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 9, Iss 1, Pp 1-10 (2020)
Clinical and Translational Medicine, Vol 9, Iss 1, Pp 1-10 (2020)
Background The Peroxisome proliferator-activated receptor gamma gene (PPARG), encodes a member of the peroxisome-activated receptor subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) which regulate transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e5f4d8bcd164d0223f15df0e32c99f
https://pubmed.ncbi.nlm.nih.gov/32064572
https://pubmed.ncbi.nlm.nih.gov/32064572