Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Polyna Khudyakov"'
Autor:
Jatinder Kaur Mukker, George Dukes, Lisi Wang, Susanna Huh, Polyna Khudyakov, Mitsuhiro Nishihara, Chunlin Chen
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 5, Pp 1281-1290 (2022)
Abstract Trazpiroben, a dopamine D2/D3 receptor antagonist under development to treat gastroparesis, displays decreasing solubility with increasing pH. This single‐sequence, open‐label, two‐period, crossover study evaluated the effect of esomep
Externí odkaz:
https://doaj.org/article/782f10a606a44a3d8fa279dc2b8f34ab
Autor:
Davaasambuu Ganmaa, Polyna Khudyakov, Uyanga Buyanjargal, Delgerekh Baigal, Munkhzul Baatar, Nomin Enkhamgalan, Sumiya Erdenebaatar, Batbayar Ochirbat, Buyankhishig Burneebaatar, Enkhtamir Purevdorj, Yanjindulam Purevsuren, Gantsetseg Garmaa, Erdenetuya Ganbaatar, Adrian R. Martineau
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background There is controversy regarding the relative influence of ‘exogenous’ versus ‘endogenous’ factors on the risk of progression from latent tuberculosis infection to active tuberculosis (TB) disease in children. Methods We con
Externí odkaz:
https://doaj.org/article/56489a62fee94d2792bd3caab1434ba7
Autor:
Archana Shrestha, Dipesh Tamrakar, Biraj Man Karmacharya, Abha Shrestha, Rajeev Shrestha, Rajendra Dev Bhatta, Prajjwal Pyakurel, Polyna Khudyakov, Vasanti Malik, Josiemer Mattei, Donna Spiegelman
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background To increase cardiovascular disease prevention efforts, worksite interventions can promote healthy food choices, facilitate health education, increase physical activity and provide social support. This pioneer study will measure th
Externí odkaz:
https://doaj.org/article/c7cdc2fd72e242ac8182a694f0f1fde4
Publikováno v:
PLoS Medicine, Vol 11, Iss 3, p e1001611 (2014)
BackgroundAllergic rhinitis, allergic dermatitis, and food allergy are extremely common diseases, especially among children, and are frequently associated to each other and to asthma. Smoking is a potential risk factor for these conditions, but so fa
Externí odkaz:
https://doaj.org/article/0fdfd90914f5472f8dad57127788e397
Autor:
Davaasambuu Ganmaa, Sabri Bromage, Polyna Khudyakov, Sumiya Erdenenbaatar, Baigal Delgererekh, Adrian R. Martineau
Publikováno v:
JAMA pediatrics.
ImportanceVitamin D deficiency (defined as 25-hydroxyvitamin D [25(OH)D] ObjectiveTo determine whether weekly oral vitamin D supplementation influences linear growth, body composition, or pubertal development in school-aged children living in a setti
Autor:
Jaya Padmanabhan, Elena Ratti, Polyna Khudyakov, Wei Yin, Stephen Zicha, Olga Golonzhka, Tairmae Kangarloo, Brian Harel, Nancy Goodman, Emmanuelle Magueur, Craig Shering, Thor Ostenfeld, Antonio Laurenza, Arthur Simen
Publikováno v:
Tuesday, April 25.
Autor:
Hakop Gevorkyan, Laura Rosen, Fahimeh Mamashli, Polyna Khudyakov, Wei Yin, Arthur A. Simen, Derek L. Buhl, Dmitri Volfson, Ferenc Martenyi
Publikováno v:
British Journal of Clinical Pharmacology. 88:600-612
Aims TAK-071 is a muscarinic M1 receptor positive allosteric modulator designed to have low cooperativity with acetylcholine. This was a first-in-human study to evaluate the safety, pharmacokinetics, and pharmacodynamics of TAK-071. Methods TAK-071 w
Autor:
Polyna Khudyakov, Maria S. Quinton, Wei Yin, Saurabh Gupta, Deborah S. Hartman, Dimitrios Arkilo, Jie Lin, Laura Rosen, Jens R. Wendland, Jim Hazel, Martin M. Bednar
Publikováno v:
British Journal of Clinical Pharmacology. 87:4756-4768
Aims Dysregulation of histone methylation epigenetic marks may result in intellectual and developmental disability, as seen in Kabuki syndrome. Animal data suggest that increasing histone methylation by inhibiting lysine-specific demethylase 1A (LSD1
Autor:
Joline W. J. Beulens, Kenneth J. Mukamal, Lars O. Dragsted, Donna Spiegelman, Diederick E. Grobbee, Howard J. Edenberg, Margaret M. Murray, Janelle W. Coughlin, Sally N. Adebamowo, Lawrence J. Appel, Eric B. Rimm, Jane N. Eriksen, Jeff D. Williamson, Ilse C. Schrieks, Polyna Khudyakov, Vilma Irazola, Ramon Estruch, Pablo Gulayin, Clement Adebamowo, John H. Krystal, T.L. Wilkens, Laura C. Lovato, Mariana Lazo
Publikováno v:
Eur J Prev Cardiol
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
European Journal of Preventive Cardiology, 27(18), 1967-1982. SAGE Publications Ltd
Spiegelman, D, Lovato, L C, Khudyakov, P, Wilkens, T L, Adebamowo, C A, Adebamowo, S N, Appel, L J, Beulens, J W J, Coughlin, J W, Dragsted, L O, Edenberg, H J, Eriksen, J N, Estruch, R, Grobbee, D E, Gulayin, P E, Irazola, V, Krystal, J H, Lazo, M, Murray, M M, Rimm, E B, Schrieks, I C, Williamson, J D & Mukamal, K J 2020, ' The Moderate Alcohol and Cardiovascular Health Trial (MACH15) : Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk ', European Journal of Preventive Cardiology, vol. 27, no. 18, pp. 1967-1982 . https://doi.org/10.1177/2047487320912376
Spiegelman, D, Lovato, L C, Khudyakov, P, Wilkens, T L, Adebamowo, C A, Adebamowo, S N, Appel, L J, Beulens, J W, Coughlin, J W, Dragsted, L O, Edenberg, H J, Eriksen, J N, Estruch, R, Grobbee, D E, Gulayin, P E, Irazola, V, Krystal, J H, Lazo, M, Murray, M M, Rimm, E B, Schrieks, I C, Williamson, J D & Mukamal, K J 2020, ' The Moderate Alcohol and Cardiovascular Health Trial (MACH15): Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk ', European Journal of Preventive Cardiology, vol. 27, no. 18, pp. 1967-1982 . https://doi.org/10.1177/2047487320912376
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
European Journal of Preventive Cardiology, 27(18), 1967-1982. SAGE Publications Ltd
Spiegelman, D, Lovato, L C, Khudyakov, P, Wilkens, T L, Adebamowo, C A, Adebamowo, S N, Appel, L J, Beulens, J W J, Coughlin, J W, Dragsted, L O, Edenberg, H J, Eriksen, J N, Estruch, R, Grobbee, D E, Gulayin, P E, Irazola, V, Krystal, J H, Lazo, M, Murray, M M, Rimm, E B, Schrieks, I C, Williamson, J D & Mukamal, K J 2020, ' The Moderate Alcohol and Cardiovascular Health Trial (MACH15) : Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk ', European Journal of Preventive Cardiology, vol. 27, no. 18, pp. 1967-1982 . https://doi.org/10.1177/2047487320912376
Spiegelman, D, Lovato, L C, Khudyakov, P, Wilkens, T L, Adebamowo, C A, Adebamowo, S N, Appel, L J, Beulens, J W, Coughlin, J W, Dragsted, L O, Edenberg, H J, Eriksen, J N, Estruch, R, Grobbee, D E, Gulayin, P E, Irazola, V, Krystal, J H, Lazo, M, Murray, M M, Rimm, E B, Schrieks, I C, Williamson, J D & Mukamal, K J 2020, ' The Moderate Alcohol and Cardiovascular Health Trial (MACH15): Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk ', European Journal of Preventive Cardiology, vol. 27, no. 18, pp. 1967-1982 . https://doi.org/10.1177/2047487320912376
Background: Observational studies have documented lower risks of coronary heart disease and diabetes among moderate alcohol consumers relative to abstainers, but only a randomized clinical trial can provide conclusive evidence for or against these as
Autor:
Wei Yin, David Han, Polyna Khudyakov, Rhett Behrje, Joel Posener, Antonio Laurenza, Dimitrios Arkilo
Publikováno v:
British journal of clinical pharmacology. 88(8)
TAK-041 (NBI-1065846), an orally available, investigational, small molecule agonist of GPR139, an orphan G-protein-coupled receptor, has shown promise in preclinical studies for the treatment of symptoms associated with schizophrenia. Here, we report