Arabidopsis N-acetyltransferase activity 2 preferentially acetylates 1,3-diaminopropane and thialysine

Autor: Roberto Mattioli (a, Gianmarco Pascarella (b, Riccardo D'Incà (a), Alessandra Cona (a, Riccardo Angelini (a, Veronica Morea (c, Paraskevi Tavladoraki (a, d

Publikováno v: Plant physiology and biochemistry (Paris) 170 (2022): 123–132. doi:10.1016/j.plaphy.2021.11.034
info:cnr-pdr/source/autori:Roberto Mattioli (a,1), Gianmarco Pascarella (b,1), Riccardo D'Incà (a), Alessandra Cona (a,d), Riccardo Angelini (a,d), Veronica Morea (c,**), Paraskevi Tavladoraki (a,d,*)/titolo:Arabidopsis N-acetyltransferase activity 2 preferentially acetylates 1,3-diaminopropane and thialysine/doi:10.1016%2Fj.plaphy.2021.11.034/rivista:Plant physiology and biochemistry (Paris)/anno:2022/pagina_da:123/pagina_a:132/intervallo_pagine:123–132/volume:170

Polyamine acetylation has an important regulatory role in polyamine metabolism. It is catalysed by GCN5-related N-acetyltransferases, which transfer acetyl groups from acetyl-coenzyme A to the primary amino groups of spermidine, spermine (Spm), or ot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2996bdf11a51ccbc8c48c8443dc82b02
https://hdl.handle.net/11590/398007

Polyamine acetylation and substrate-induced oligomeric states in histone acetyltransferase of multiple drug resistant Acinetobacter baumannii

Autor: Jyoti Singh Tomar, Ramakrishna V. Hosur

Publikováno v: Biochimie. 168:268-276

Histone acetyltransferase (Hpa2) is an unusual acetyltransferase, with a wide range of substrates; including histones, polyamines and aminoglycosides antibiotic. Hpa2 belongs to GNAT superfamily and GNATs are well known for the formation of homo-olig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380c654ff9b0722ec306deedf4547515
https://doi.org/10.1016/j.biochi.2019.11.015

Analysis of crystalline and solution states of ligand-free spermidineN-acetyltransferase (SpeG) fromEscherichia coli

Autor: Steven Weigand, Wayne F. Anderson, Olga Kiryukhina, Ekaterina V. Filippova, Alan J. Wolfe

Publikováno v: Acta Crystallogr D Struct Biol

SpermidineN-acetyltransferase (SpeG) transfers an acetyl group from acetyl-coenzyme A to an N-terminal amino group of intracellular spermidine. This acetylation inactivates spermidine, reducing the polyamine toxicity that tends to occur under certain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a68073cb27e1d96e0bacad2d9597c33
https://doi.org/10.1107/s2059798319006545

Polyamine Deacetylase Structure and Catalysis: Prokaryotic Acetylpolyamine Amidohydrolase and Eukaryotic HDAC10

Autor: Stephen A. Shinsky, David W. Christianson

Polyamines such as putrescine, spermidine, and spermine are small aliphatic cations that serve myriad biological functions in all forms of life. While polyamine biosynthesis and cellular trafficking pathways are generally well defined, it is only rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016237ad3b6b0d97ce7ba73ded4ff6b7
https://europepmc.org/articles/PMC5988950/

Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis

Autor: Manoocher Soleimani, Kamyar Zahedi, Salim Merali, Oscar Perez-Leal, Carl W. Porter, Chunli Liu, Carlos A. Barrero

Publikováno v: Amino Acids. 46:701-715

The continued rise in obesity despite public education, awareness and policies indicates the need for mechanism-based therapeutic approaches to help control the disease. Our data, in conjunction with other studies, suggest an unexpected role for the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b686794565039fc9570a91414b39342e
https://doi.org/10.1007/s00726-013-1548-3