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Akademický článek

Inhibition of mitochondrial complex III or dihydroorotate dehydrogenase (DHODH) triggers formation of poly(A)+ RNA foci adjacent to nuclear speckles following activation of ATM (ataxia telangiectasia mutated)

Autor: Shuntaro Miyake, Seiji Masuda

Publikováno v: RNA Biology, Vol 19, Iss 1, Pp 1244-1255 (2022)

Intracellular and intercellular signalling networks play an essential role in optimizing cellular homoeostasis and are thought to be partly reflected in nuclear mRNA dynamics. However, the regulation of nuclear mRNA dynamics by intracellular and inte

Externí odkaz: https://doaj.org/article/5388c98c77574fcea700c289421f350e

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Akademický článek

The enigma of ultraviolet radiation stress granules: Research challenges and new perspectives

Autor: Alexandra J. Cabral, Danielle C. Costello, Natalie G. Farny

Publikováno v: Frontiers in Molecular Biosciences, Vol 9 (2022)

Stress granules (SGs) are non-membrane bound cytoplasmic condensates that form in response to a variety of different stressors. Canonical SGs are thought to have a cytoprotective role, reallocating cellular resources during stress by activation of th

Externí odkaz: https://doaj.org/article/077117bad52a4c2c9beebb6366739a79

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Akademický článek

Salivary microRNA profiling dysregulation in autism spectrum disorder: A pilot study

Autor: Zamira Kalemaj, Maria Michela Marino, Annamaria Chiara Santini, Giovanni Tomaselli, Amogh Auti, Maria Grazia Cagetti, Tiziana Borsello, Antonella Costantino, Francesco Inchingolo, Mariarosaria Boccellino, Marina Di Domenico, Gianluca Martino Tartaglia

Publikováno v: Frontiers in Neuroscience, Vol 16 (2022)

IntroductionAutism spectrum disorders (ASD) are the most prevalent neurobiological disorders in children. The etiology comprises genetic, epigenetic, and environmental factors such as dysfunction of the immune system. Epigenetic mechanisms are mainly

Externí odkaz: https://doaj.org/article/4c863b18b7a247afaeb8fd0f1dd7e9c9

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Akademický článek

An Efficient Method to Prepare Barcoded cDNA Libraries from Plant Callus for Long-Read Sequencing

Autor: Daniela Cordeiro, Alexandra Camelo, Ana Carolina Pedrosa, Inês Brandão, Jorge Canhoto, Christophe Espírito Santo, Sandra Correia

Publikováno v: Methods and Protocols, Vol 6, Iss 2, p 31 (2023)

Long-read sequencing methods allow a comprehensive analysis of transcriptomes in identifying full-length transcripts. This revolutionary method represents a considerable breakthrough for non-model species since it allows enhanced gene annotation and

Externí odkaz: https://doaj.org/article/48423add025d45c5b08ccf5535247517

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Akademický článek

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Dissertation/ Thesis

Sample DNA Recovery Utilizing Poly (A) RNA Carrier on Cotton Swabs

Autor: Paul, Thomas

Low quantities of DNA are problematic for forensic science because it leads to no or poor profile quality. Low quantity samples and samples that may start off with borderline, but sufficient, quantities of DNA are especially problematic as DNA is eas

Externí odkaz: http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1679530531110524