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In vitro response of THP-1 derived macrophages to antimicrobially effective PHMB-coated Ti6Al4V alloy implant material with and without contamination with S. epidermidis and P. aeruginosa

Autor: Paula Zwicker, Thomas Schmidt, Melanie Hornschuh, Holger Lode, Axel Kramer, Gerald Müller

Publikováno v: Biomaterials Research
Biomaterials Research, Vol 26, Iss 1, Pp 1-13 (2022)

Aim Periprosthetic joint infections are a devastating complication after arthroplasty, leading to rejection of the prosthesis. The prevention of septic loosening may be possible by an antimicrobial coating of the implant surface. Poly (hexamethylene)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f1a6960e548a10ca1a2d94d12b7e80
https://pubmed.ncbi.nlm.nih.gov/35000621

Study of Epigenetic Properties of Poly(HexaMethylene Biguanide) Hydrochloride (PHMB)

Autor: Aboudoulatif Diallo, Christophe Eklu-Gadegbeku, Daniel Cros, Serge Moukha, Edmond E. Creppy

Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, MDPI, 2014, 11 (8), pp.8069-8092. ⟨10.3390/ijerph110808069⟩
International Journal of Environmental Research and Public Health, Vol 11, Iss 8, Pp 8069-8092 (2014)
International Journal of Environmental Research and Public Health 8 (11), 8069-8092. (2014)
International Journal of Environmental Research and Public Health; Volume 11; Issue 8; Pages: 8069-8092

International audience; Poly(HexaMethylene Biguanide) hydrochloride (PHMB) CAS No. [32289-58-0] is a particularly effective member of the biguanides antiseptic chemical group, and has been in use since the early fifties in numerous applications. It h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6742bb5da99aceb19263c163c7f6a4
http://europepmc.org/articles/PMC4143850

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