Výsledky vyhledávání - "Polonikov, A."

Akademický článek

NADPH oxidase 5 is a novel susceptibility gene for type 2 diabetes mellitus

Autor: Iuliia Azarova, Elena Klyosova, Valentina Azarova, Alexey Polonikov

Publikováno v: Archives of Endocrinology and Metabolism, Vol 68 (2024)

ABSTRACT Objective This pilot study investigated whether single nucleotide polymorphisms (SNP) in the NOX5 gene (NADPH oxidase 5) are associated with the type 2 diabetes (T2D) risk. Subjects and methods A total of 1579 patients with T2D and 1627 age-

Externí odkaz: https://doaj.org/article/551df442a59540f0b8b863c71b680c45

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Akademický článek

Association of genotypes of biotransformation enzymes with susceptibility to chronic pulmonary tuberculosis

Autor: Maxim A. Alymenko, Ravil Sh. Valiev, Nail R. Valiev, Natalya P. Balobanova, Alexander V. Batishchev, Irina N. Tragira, Viacheslav A. Lipatov, Alexey V. Polonikov, Vladislav M. Kolomiets, Svetlana N. Volkova, Galina S. Mal, Vera A. Ragulina

Publikováno v: Consilium Medicum, Vol 26, Iss 03, Pp 193-198 (2024)

Background. Now it is well-known that the pulmonary tuberculosis is a multifactorial disease in which forming a certain role belongs as factors external the environment, and genetic to factors. Aim. In this study, the association of genes of xenob

Externí odkaz: https://doaj.org/article/663a97a85e8d4a8c80363e486835a834

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Akademický článek

The Promoter Polymorphism rs3918226 of the Endothelial Nitric Oxide Synthase Gene as a Novel Susceptibility Marker for Peripheral Artery Disease

Autor: Zhabin, Sergey, Lazarenko, Victor, Azarova, Iulia, Klyosova, Elena, Bashkatov, Daniil, Kononov, Stanislav, Dolgintsev, Maxim, Churnosov, Mikhail, Solodilova, Maria, Polonikov, Alexey

Publikováno v: In Annals of Vascular Surgery November 2024 108:557-563

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Akademický článek

Association of polymorphic variants of genes of xenobiotic biotransformation enzymes with susceptibility to pulmonary tuberculosis, taking into account gender features

Autor: M. A. Alymenko, R. Sh. Valiev, N. R. Valiev, A. V. Polonikov, V. M. Kolomiets, I. N. Tragira, V. A. Ragulina, G. S. Mal, E. V. Popova, N. P. Balobanova, A. V. Batishchev

Publikováno v: Сибирский научный медицинский журнал, Vol 44, Iss 1, Pp 204-210 (2024)

Aim of the study was to investigate susceptibility to pulmonary tuberculosis in men and women depending on polymorphism of genes of xenobiotic biotransformation enzymes NAT2 (590G> A (rs1799930)), CYP2E1 (9896C> G (rs2070676)), ABCB1 (3435T> C (rs104

Externí odkaz: https://doaj.org/article/512950aacf39454687455e7aea5493b7

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Akademický článek

Polymorphism rs143384 GDF5 reduces the risk of knee osteoarthritis development in obese individuals and increases the disease risk in non-obese population

Autor: Vitaly Novakov, Olga Novakova, Maria Churnosova, Inna Aristova, Marina Ponomarenko, Yuliya Reshetnikova, Vladimir Churnosov, Inna Sorokina, Irina Ponomarenko, Olga Efremova, Valentina Orlova, Irina Batlutskaya, Alexey Polonikov, Evgeny Reshetnikov, Mikhail Churnosov

Publikováno v: Arthroplasty, Vol 6, Iss 1, Pp 1-14 (2024)

Abstract Background We investigated the effect of obesity on the association of genome-wide associative studies (GWAS)-significant genes with the risk of knee osteoarthritis (KOA). Methods All study participants (n = 1,100) were divided into 2 groups

Externí odkaz: https://doaj.org/article/f76096b074c448b298fb6da7c84c28e3

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Akademický článek

The effect of Polymorphism of the MDR1 (ABCB1) Gene on the Risk of Hepatotoxic Reactions in Patients with Pulmonary Tuberculosis

Autor: М. А. Alymenko, R. Sh. Valiev, N. R. Valiev, I. N. Tragira, А. V. Polonikov, N. Р. Balobanova, A. V. Batishchev, V. М. Kolomiets, G. S. Mal, S. N. Volkova, V. V. Kozlov, E. I. Suslikova, E. V. Popova

Publikováno v: Антибиотики и Химиотерапия, Vol 68, Iss 7-8, Pp 62-69 (2023)

Currently, a decrease is seen in the effectiveness of treatment in patients with tuberculosis due to the appearance of adverse reactions to anti-tuberculosis drugs. Hepatotoxic reactions play an especially important role in anti-tuberculosis therapy,

Externí odkaz: https://doaj.org/article/9e6f4aaf6e4a48ea96abf6242c4a60d1

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Akademický článek

The discovery of GGT1 as a novel gene for ischemic stroke conferring protection against disease risk in non-smokers and non-abusers of alcohol

Autor: Solodilova, Maria, Drozdova, Elena, Azarova, Iuliia, Klyosova, Elena, Bykanova, Marina, Bushueva, Olga, Polonikova, Anna, Churnosov, Mikhail, Polonikov, Alexey

Publikováno v: In Journal of Stroke and Cerebrovascular Diseases June 2024 33(6)

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Akademický článek

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Akademický článek

Polymorphism of SERF2, the gene encoding a heat-resistant obscure (Hero) protein with chaperone activity, is a novel link in ischemic stroke

Autor: Andrei E. Belykh, Vladislav O. Soldatov, Tatiana A. Stetskaya, Ksenia A. Kobzeva, Maria O. Soldatova, Alexey V. Polonikov, Alexey V. Deykin, Mikhail I. Churnosov, Maxim B. Freidin, Olga Y. Bushueva, Dr.

Publikováno v: IBRO Neuroscience Reports, Vol 14, Iss , Pp 453-461 (2023)

Background: Ischemic stroke (IS) is one of the most serious cardiovascular events associated with high risk of death or disability. The growing body of evidence highlights molecular chaperones as especially important players in the pathogenesis of th

Externí odkaz: https://doaj.org/article/6b944a4a05384e77a165ff68452d9a39

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