Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Polly Talley"'
Autor:
Andrew Clark, Sally Thomas, Angela Hamblin, Polly Talley, Austin Kulasekararaj, Jacob Grinfeld, Beverley Speight, Katie Snape, Terri P. McVeigh, John A. Snowden
Publikováno v:
British Journal of Haematology. 201:35-44
Autor:
Nick Telford, Nicole Dastugue, Michael R. Stratton, Paul Sinclair, Yang Li, Peter Vandenberghe, Richard J. Q. McNally, Fiona M. Ross, Patricia Jacobs, Nyla A. Heerema, Christine J. Harrison, Julian Borrow, Peter Van Loo, Olivia Joseph, Vikki Rand, Polly Talley, Philip J. Stephens, Bryan D. Young, Claire Schwab, Nick Bown, Mark Maddison, Andrew J. Carroll, Hazel M. Robinson, Anthony V. Moorman, Claudia Haferlach, Elli Papaemmanuil, Mike Griffiths, Peter J. Campbell, Lorraine Gaunt, Ben Robinson, Sarra Ryan, Sara Dyer, Manuel R. Teixeira, Jiqiu Cheng
Publikováno v:
Nature
Changes in gene dosage are a major driver of cancer, known to be caused by a finite, but increasingly well annotated, repertoire of mutational mechanisms1. This can potentially generate correlated copy-number alterations across hundreds of linked gen
Autor:
Jozef Gecz, Grant R. Sutherland, Nicholas K. Moschonas, Edna L Maltby, Stefan Gesk, Elizabeth Baker, Lisa French, Kerstin Kutsche, Theologia Sarafidou, Polly Talley, Merran Finnis, Lana Harder, Maria Kokkinaki, Carlo Nobile, Panagiotis Deloukas, Reiner Siebert, Christina Kahl, Kathy Richkind, Marie Mangelsdorf, Bernd Hinzmann, Isabel Martinez-Garay
Fragile sites appear visually as nonstaining gaps on chromosomes that are inducible by specific cell culture conditions. Expansion of CGG/CCG repeats has been shown to be the molecular basis of all five folate-sensitive fragile sites characterized mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698d015f8ff4990f73d731473e6e5133
https://doi.org/10.1016/j.ygeno.2003.12.017
https://doi.org/10.1016/j.ygeno.2003.12.017
Autor:
John Swansbury, Nick Bown, Sue Richards, Zoe J. Konn, Polly Talley, Sarah L. Wright, Christine J. Harrison, M Martineau
This study describes the cytogenetics of 33 children with ETV6-RUNX1 positive acute lymphoblastic leukemia (ALL) who had been in continuous complete remission for a minimum of 8.8 years [median event-free survival (EFS) 10.9 years]. The results were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60933677fee72f352dd53709cbc0510
https://ora.ox.ac.uk/objects/uuid:63ae26e8-6862-4f96-a92b-baacc71b4fe9
https://ora.ox.ac.uk/objects/uuid:63ae26e8-6862-4f96-a92b-baacc71b4fe9
Autor:
K. McCarthy, Mitchell S. Cairo, Anne Auperin, E. Launay, Mary Gerrard, Sherrie L. Perkins, Richard Sposto, Warren G. Sanger, John Swansbury, Nyla A. Heerema, Martine Raphael, Alain Bernheim, Polly Talley, Hélène Poirel, Catherine Patte
Publikováno v:
Leukemia
Clinical studies showed that advanced stage, high LDH, poor response to reduction therapy and combined bone marrow and central nervous system disease are significantly associated with a decreased event-free survival (EFS) in pediatric mature B-cell n
Autor:
Marzena Flasza, Peter W. Andrews, Polly Talley, Penny A. Johnson, Kath Smith, Andrew Ferguson Shering
Publikováno v:
Cloning and Stem Cells. 5:339-354
Somatic cell reprogramming holds great promise for the development of novel cellular therapeutics. A number of sources of reprogramming potential have been identified, including oocytes, embryonic germ (EG) cells and embryonic stem (ES) cells. Howeve
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 15:e110-e111
Publikováno v:
Cancer Genetics and Cytogenetics. 163:71-73
Congenital leukemia occurring within 4 weeks of birth is extremely rare and, excluding transient neonatal myeloproliferation associated with Down syndrome, makes up approximately 1% of childhood leukemias. It is usually seen as acute myeloid leukemia
Autor:
Anthony V. Moorman, Hazel M. Robinson, F W van Delft, Helen Worley, Christine J. Harrison, Sarah Wright, Jonathan C. Strefford, G Bettney, Fiona M. Ross, Vaskar Saha, Teresa Davies, Adam R. M. Stewart, Sandra Hing, Polly Talley, Mike Griffiths, Mark G. Atherton, Kerry E. Barber
Publikováno v:
Oncogene. 26(29)
Chromosomal abnormalities are important for the classification and risk stratification of patients with acute lymphoblastic leukemia (ALL). However, approximately 30% of childhood and 50% of adult patients lack abnormalities with clinical relevance.
Autor:
Florence Nguyen-Khac, Debra M. Lillington, Lana Harder, Theodore Balasas, E. Loraine Karran, Aneela Majid, Stéphanie Struski, Mark G. Atherton, Polly Talley, María José Calasanz, Jonathan C. Strefford, Renata Walewska, Helen Worley, Anne Hagemeijer, Isabelle Radford-Weiss, José I. Martín-Subero, Keiji Sugimoto, Helena Kempski, Melanie J. Welham, Michel Lessard, Takashi Akasaka, Teresa Davies, Sarah Moore, Oskar A. Haas, Christine J. Harrison, David Brown, Claudia Schoch, Reiner Siebert, Monika Brüggemann, Lisa J. Russell, Martin J. S. Dyer, Stefan Gesk, Kelvin Cain
Publikováno v:
Blood. 109(8)
CCAAT enhancer-binding protein (CEBP) transcription factors play pivotal roles in proliferation and differentiation, including suppression of myeloid leukemogenesis. Mutations of CEBPA are found in a subset of acute myeloid leukemia (AML) and in some