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Autor:
Jean M. H. van den Elsen, Hannah B. L. Jones, Omar Kassaar, Michael J Knight, Christina E. Gulácsy, Andrew G. Watts, Rachel E Woolley, Stephen A. Wells, Stuart Parsons, Elizabeth Rodriguez, Polly Phaal, Andreia Marques, Anthony Kwok, Alison Turner, John O'Hara, Christopher R. Pudney, Leo A Bowsher, Kieran Dawkins
Publikováno v:
Biochemical Journal
Among the major challenges in the development of biopharmaceuticals are structural heterogeneity and aggregation. The development of a successful therapeutic monoclonal antibody (mAb) requires both a highly active and also stable molecule. Whilst a r