Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Polly Matzinger"'
Autor:
Elana R. Shaw, Polly Matzinger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The Danger Model predicts that there are some molecules that no immune system can ever be fully tolerant of, namely proteins that are only transiently expressed during times of stress, infection, or injury. Among these are the danger/alarm signals th
Externí odkaz:
https://doaj.org/article/4268debb0355461293292aa9211c50dc
Autor:
Polly Matzinger
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
For decades, the main question immunologists have asked about autoimmunity is “what causes a break in self-tolerance?” We have not found good answers to that question, and I believe we are still so ignorant because it’s the wrong question. Rath
Externí odkaz:
https://doaj.org/article/21efb28d91df4dec8f8c0d0a482fc458
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/250cca1074e4442c95e4b8a11c77aecc
Autor:
Luisa Möhle, Daniele Mattei, Markus M. Heimesaat, Stefan Bereswill, André Fischer, Marie Alutis, Timothy French, Dolores Hambardzumyan, Polly Matzinger, Ildiko R. Dunay, Susanne A. Wolf
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1945-1956 (2016)
Antibiotics, though remarkably useful, can also cause certain adverse effects. We detected that treatment of adult mice with antibiotics decreases hippocampal neurogenesis and memory retention. Reconstitution with normal gut flora (SPF) did not compl
Externí odkaz:
https://doaj.org/article/3fc4f71ac6df4652a705518f4530a785
Autor:
Kaveh Abdi, Tsute Chen, Brian A Klein, Albert K Tai, Jill Coursen, Xiangdong Liu, Jeff Skinner, Saravanan Periasamy, Youngnim Choi, Benedikt M Kessler, Robert J Palmer, Apostolos Gittis, Polly Matzinger, Margaret J Duncan, Nevil J Singh
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182164 (2017)
The oral cavity is home to unique resident microbial communities whose interactions with host immunity are less frequently studied than those of the intestinal microbiome. We examined the stimulatory capacity and the interactions of two oral bacteria
Externí odkaz:
https://doaj.org/article/36a174eb71514f4389dda76bff7d88b4
Fig S1 shows that sorted CD4 T cells used in Figure 2 lack APCFig S2 shows that CD4 T cells in all chimeric mice shown in Figure 3 were primed by the immunizationsFig S3 shows that CD4 T cells first arrive at the tumor site around day 6Fig S4 shows t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1861acf9bdf93979a798ae71c5a9eca9
https://doi.org/10.1158/2767-9764.22544697.v1
https://doi.org/10.1158/2767-9764.22544697.v1
Publikováno v:
Cancer Res Commun
Tumor-associated macrophages (TAM) promote tumor survival, angiogenesis, and metastases. Although they express MHC class II molecules, little is known about their ability to present tumor antigens to tumor-infiltrating CD4 T cells, and the consequenc
Autor:
Zachary M. Earley, Wioletta Lisicka, Joseph J. Sifakis, Raúl Aguirre-Gamboa, Anita Kowalczyk, Jacob T. Barlow, Dustin G. Shaw, Valentina Discepolo, Ineke L. Tan, Saideep Gona, Jordan D. Ernest, Polly Matzinger, Luis B. Barreiro, Andrey Morgun, Albert Bendelac, Rustem F. Ismagilov, Natalia Shulzhenko, Samantha J. Riesenfeld, Bana Jabri
Publikováno v:
Immunity. 56:43-57.e10
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Publikováno v:
ImmunoHorizons. 4:415-419
Dendritic cells (DCs) play a key role in the initiation of an immune response and are known as “professional” APCs because of their ability to activate naive T cells. A widely used method to generate DCs in vitro is to culture bone marrow (BM) ce