Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Polly M Fordyce"'
Autor:
Jamin B Hein, Hieu T Nguyen, Dimitriya H Garvanska, Isha Nasa, Thomas Kruse, Yinnian Feng, Blanca Lopez Mendez, Norman Davey, Arminja N Kettenbach, Polly M Fordyce, Jakob Nilsson
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 12, Pp n/a-n/a (2023)
Abstract Phosphoprotein phosphatases (PPPs) regulate major signaling pathways, but the determinants of phosphatase specificity are poorly understood. This is because methods to investigate this at scale are lacking. Here, we develop a novel in vitro
Externí odkaz:
https://doaj.org/article/2b7f9cdcf70344a5bb703577c2b23118
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007884 (2018)
The Sterol Regulatory Element Binding Proteins (SREBPs) are basic-helix-loop-helix transcription regulators that control the expression of sterol biosynthesis genes in higher eukaryotes and some fungi. Surprisingly, SREBPs do not regulate sterol bios
Externí odkaz:
https://doaj.org/article/a431b4f0a48e431a90329430d38cee4c
Autor:
Kara Brower, Robert R. Puccinelli, Craig J. Markin, Tyler C. Shimko, Scott A. Longwell, Bianca Cruz, Rafael Gomez-Sjoberg, Polly M. Fordyce
Publikováno v:
HardwareX, Vol 3, Iss , Pp 117-134 (2018)
Microfluidic technologies have been used across diverse disciplines (e.g. high-throughput biological measurement, fluid physics, laboratory fluid manipulation) but widespread adoption has been limited in part due to the lack of openly disseminated re
Externí odkaz:
https://doaj.org/article/c2ebeef00ba34878b2ec942257f44782
Autor:
Qitong Li, Jorik van de Groep, Adam K. White, Jung-Hwan Song, Scott A. Longwell, Polly M. Fordyce, Stephen R. Quake, Pieter G. Kik, Mark L. Brongersma
Publikováno v:
Nature Nanotechnology, 17(10). Nature Publishing Group
The ability to manipulate light and liquids on integrated optofluidics chips has spurred a myriad of important developments in biology, medicine, chemistry and display technologies. Here we show how the convergence of optofluidics and metasurface opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dc3a906e9cfcb309c482afb1fc6a36
https://doi.org/10.1038/s41565-022-01197-y
https://doi.org/10.1038/s41565-022-01197-y
Publikováno v:
Nature Methods. 19:1295-1305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::195c526238c23deaf400164041e5f14a
https://doi.org/10.1038/s41592-022-01592-2
https://doi.org/10.1038/s41592-022-01592-2
Autor:
Jamin B. Hein, Hieu T. Nguyen, Dimitriya H. Garvanska, Isha Nasa, Yinnian Feng, Blanca Lopez Mendez, Norman Davey, Arminja N Kettenbach, Polly M. Fordyce, Jakob Nilsson
Phosphoprotein phosphatases (PPPs) dephosphorylate Serine (Ser)/Threonine (Thr) residues to regulate major signaling pathways and cellular transitions. Despite the central role of PPPs the substrates in most cellular processes and the determinants of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a976596080a1b5a789e397db127764c
https://doi.org/10.1101/2023.05.14.540683
https://doi.org/10.1101/2023.05.14.540683
Autor:
Amr M. Alexandari, Connor A. Horton, Avanti Shrikumar, Nilay Shah, Eileen Li, Melanie Weilert, Miles A. Pufall, Julia Zeitlinger, Polly M. Fordyce, Anshul Kundaje
Transcription factors (TF) are proteins that bind DNA in a sequence-specific manner to regulate gene transcription. Despite their unique intrinsic sequence preferences,in vivogenomic occupancy profiles of TFs differ across cellular contexts. Hence, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08bc1e3a7387839e6c11d4e259319e73
https://doi.org/10.1101/2023.05.11.540401
https://doi.org/10.1101/2023.05.11.540401
Publikováno v:
ISME Communications. 3
Our understanding ofin situmicrobial physiology is primarily based on physiological characterization of fast-growing and readily-isolatable microbes. Microbial enrichments to obtain novel isolates with slower growth rates or physiologies adapted to l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34f77364e32d10e61e1446d7f9c3b85
https://doi.org/10.1038/s43705-023-00241-9
https://doi.org/10.1038/s43705-023-00241-9
Autor:
Suzanne G. K. Calhoun, Kara K. Brower, Vineeth Chandran Suja, Gaeun Kim, Ningning Wang, Alexandra L. McCully, Halim Kusumaatmaja, Gerald G. Fuller, Polly M. Fordyce
Publikováno v:
Lab on a Chip, 2022, Vol.22(12) [Peer Reviewed Journal]
Double emulsion droplets (DEs) are water/oil/water droplets that can be sorted via fluorescence-activated cell sorting (FACS), allowing for new opportunities in high-throughput cellular analysis, enzymatic screening, and synthetic biology. These appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0029ee9d6fec81b29783126957d93584
https://doi.org/10.1039/d2lc00229a
https://doi.org/10.1039/d2lc00229a
Publikováno v:
Curr Opin Struct Biol
Accurate predictions from models based on physical principles are the ultimate metric of our biophysical understanding. Although there has been stunning progress toward structure prediction, quantitative prediction of enzyme function has remained cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b450fe685fa4ab5b7d7fcff742d791f0
https://doi.org/10.1016/j.sbi.2021.07.010
https://doi.org/10.1016/j.sbi.2021.07.010