Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab

Autor: Kennedy, Nicholas A, Goodhand, James R, Bewshea, Claire, Nice, Rachel, Chee, Desmond, Lin, Simeng, Chanchlani, Neil, Butterworth, Jeffrey, Cooney, Rachel, Croft, Nicholas M, Hart, Ailsa L, Irving, Peter M, Kok, Klaartje B, Lamb, Christopher A, Limdi, Jimmy K, Macdonald, Jonathan, McGovern, Dermot Pb, Mehta, Shameer J, Murray, Charles D, Patel, Kamal V, Pollok, Richard Cg, Raine, Timothy, Russell, Richard K, Selinger, Christian P, Smith, Philip J, Bowden, Jack, McDonald, Timothy J, Lees, Charlie W, Sebastian, Shaji, Powell, Nicholas, Ahmad, Tariq, Contributors To The CLARITY IBD Study

Publikováno v: 2021, ' Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab ', Gut, vol. 70, no. 5, pp. 865-875 . https://doi.org/10.1136/gutjnl-2021-324388
Gut

ObjectiveAntitumour necrosis factor (anti-TNF) drugs impair protective immunity following pneumococcal, influenza and viral hepatitis vaccination and increase the risk of serious respiratory infections. We sought to determine whether infliximab-treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6e01dd054652cb9b8697520d2d594a
https://hdl.handle.net/20.500.11820/1bfd49d0-2ff9-4251-9b80-3c64409dface

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Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab.

Autor: Kennedy NA; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Goodhand JR; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Bewshea C; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Nice R; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK.; Department of Biochemistry, Exeter Clinical Laboratory International, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., Chee D; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Lin S; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Chanchlani N; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Butterworth J; Department of Gastroenterology, Shrewsbury and Telford Hospital NHS Trust, Shrewsbury, UK., Cooney R; Department of Gastroenterology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Croft NM; Department of Paediatric Gastroenterology, Royal London Hospital, Barts Health NHS Trust, London, UK.; Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK., Hart AL; Department of Gastroenterology, St Mark's Hospital and Academic Institute, Harrow, London, UK., Irving PM; Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.; School of Immunology & Microbial Sciences, King's College London, London, UK., Kok KB; Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.; Department of Gastroenterology, Royal London Hospital, Barts Health NHS Trust, London, UK., Lamb CA; Department of Gastroenterology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Limdi JK; Department of Gastroenterology, Pennine Acute Hospitals NHS Trust, Manchester, UK.; Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK., Macdonald J; Department of Gastroenterology, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK., McGovern DP; F. Widjaja Foundation Inflammatory Bowel and Immunology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Mehta SJ; Department of Gastroenterology, University College London Hospitals NHS Foundation Trust, London, UK., Murray CD; Department of Gastroenterology, Royal Free London NHS Foundation Trust, London, UK., Patel KV; Department of Gastroenterology, St George's University Hospitals NHS Foundation Trust, London, UK., Pollok RC; Department of Gastroenterology, St George's University Hospitals NHS Foundation Trust, London, UK.; Institute for Infection and Immunity, University of London, London, UK., Raine T; Department of Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Russell RK; Department of Paediatric Gastroenterology, Royal Hospital for Sick Children, NHS Lothian, Edinburgh, UK., Selinger CP; Department of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UK., Smith PJ; Department of Gastroenterology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Bowden J; Medical School, University of Exeter, Exeter, UK., McDonald TJ; Department of Biochemistry, Exeter Clinical Laboratory International, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., Lees CW; Department of Gastroenterology, Western General Hospital, NHS Lothian, Edinburgh, UK.; Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Sebastian S; Department of Gastroenterology, Hull University Teaching Hospitals NHS Trust, Hull, UK., Powell N; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Ahmad T; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK tariq.ahmad1@nhs.net.; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK.

Publikováno v: Gut [Gut] 2021 May; Vol. 70 (5), pp. 865-875. Date of Electronic Publication: 2021 Mar 22.