Broad spectrum regulation of non receptor tyrosine kinases by the bacterial ADP ribosyltransferase EspJ

Autor: Pollard, Dominic J., Berger, Cedric N., So, Ernest C., Yu, Lu, Hadavizadeh, Kate, Jennings, Patricia, Tate, Edward W., Choudhary, Jyoti S., Frankel, Gad

Publikováno v: mBio, Vol 9, Iss 2 (2018)

Tyrosine phosphorylation is key for signal transduction from exogenous stimuli, including the defense against pathogens. Conversely, pathogens can subvert protein phosphorylation to control host immune responses and facilitate invasion and disseminat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::da8b52a71388bdc01a5b6de87d3ef247
http://hdl.handle.net/10044/1/57875

The Type III Secretion System Effector SeoC of Salmonella enterica subsp. salamae and S. enterica subsp. arizonae ADP-Ribosylates Src and Inhibits Opsonophagocytosis

Autor: Pollard, Dominic J, Young, Joanna C, Covarelli, Valentina, Herrera-Leon, Silvia, Connor, Thomas R, Fookes, Maria, Walker, Danielle, Echeita, Aurora, Thomson, Nicholas R, Berger, Cedric N, Frankel, Gad

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Pollard, D J, Young, JC, Covarelli, V, Herrera-León, S, Connor, T R, Fookes, M, Walker, D, Echeita, A, Thomson, N R, Berger, C N & Frankel, G 2016, ' The type III secretion system effector SeoC of salmonella enterica subsp. salamae and S. enterica subsp. arizonae ADP-Ribosylates Src and inhibits opsonophagocytosis ', Infection and Immunity, vol. 84, no. 12, pp. 3618-3628 . https://doi.org/10.1128/iai.00704-16
Infection and Immunity

Salmonella species utilize type III secretion systems (T3SSs) to translocate effectors into the cytosol of mammalian host cells, subverting cell signaling and facilitating the onset of gastroenteritis. In this study, we compared a draft genome assemb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::15b5a5bfbdeae0c50f0c92beaaa591de
http://hdl.handle.net/20.500.12105/11496

The Type III Secretion System Effector SeoC of Salmonella entericasubsp. salamaeand S. entericasubsp. arizonaeADP-Ribosylates Src and Inhibits Opsonophagocytosis

Autor: Pollard, Dominic J., Young, Joanna C., Covarelli, Valentina, Herrera-León, Silvia, Connor, Thomas R., Fookes, Maria, Walker, Danielle, Echeita, Aurora, Thomson, Nicholas R., Berger, Cedric N., Frankel, Gad

Publikováno v: Infection and Immunity; September 2016, Vol. 84 Issue: 12 p3618-3628, 11p

The Type III Secretion System Effector SeoC of Salmonella enterica subsp. salamae and S. enterica subsp. arizonae ADP-Ribosylates Src and Inhibits Opsonophagocytosis.

Autor: Pollard DJ; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, United Kingdom., Young JC; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, United Kingdom., Covarelli V; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, United Kingdom., Herrera-León S; Sección de Enterobacterias, Servicio de Bacteriología, Centro Nacional de Microbiología, ISCIII, Majadahonda, Spain., Connor TR; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom., Fookes M; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom., Walker D; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom., Echeita A; Sección de Enterobacterias, Servicio de Bacteriología, Centro Nacional de Microbiología, ISCIII, Majadahonda, Spain., Thomson NR; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.; The London School of Hygiene and Tropical Medicine, London, United Kingdom., Berger CN; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, United Kingdom., Frankel G; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, United Kingdom g.frankel@imperial.ac.uk.

Publikováno v: Infection and immunity [Infect Immun] 2016 Nov 18; Vol. 84 (12), pp. 3618-3628. Date of Electronic Publication: 2016 Nov 18 (Print Publication: 2016).