Zobrazeno 1 - 10
of 513
pro vyhledávání: '"Pollara, P."'
Autor:
Maphe Mthembu, Helgard Claassen, Sharon Khuzwayo, Valentin Voillet, Anneta Naidoo, Jule S. Spillner, Kennedy Nyamande, Dilshaad Fakey Khan, Priya Maharaj, Mohammed Mitha, Zoey Mhlane, Farina Karim, Erica Andersen-Nissen, Thumbi Ndung’u, Gabriele Pollara, Emily B. Wong
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111137- (2024)
Summary: HIV causes susceptibility to respiratory pathogens, including tuberculosis (TB), but the underlying immunological mechanisms remain incompletely understood. We obtained whole blood and bronchoalveolar lavage (BAL) from TB-exposed people in t
Externí odkaz:
https://doaj.org/article/56b137e67153442bab5a1ed3b3f5968e
Autor:
Pamela N. Peters, Regina S. Whitaker, Felicia Lim, Shonagh Russell, Elizabeth A. Bloom, Justin Pollara, Kyle C. Strickland, Mark J. Cantwell, Amer Beg, Andrew Berchuck, Scott Antonia, Rebecca A. Previs
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 57, Iss , Pp 101056- (2024)
Single agent immune checkpoint inhibitors have been ineffective for patients with advanced stage and recurrent high grade serous ovarian cancer (HGSOC). Using pre-clinical models of HGSOC, we evaluated the anti-tumor and immune stimulatory effects of
Externí odkaz:
https://doaj.org/article/6671225534084b968c89f7e95e76d5ae
Autor:
Melissa J. Harnois, Richard Barfield, Maria Dennis, Nicole Rodgers, Justin Pollara, Connor S. Spies, Laurie D. Snyder, Cliburn Chan, Annette M. Jackson, Scott M. Palmer, Sallie R. Permar
Publikováno v:
JHLT Open, Vol 5, Iss , Pp 100113- (2024)
Background: Cytomegalovirus (CMV) is the most common viral infection among lung transplant recipients and is associated with chronic lung allograft dysfunction. There is a need for better therapeutics as well as biomarkers to enable effective stratif
Externí odkaz:
https://doaj.org/article/c5618eb61e9b4a18b13209e6e2b2f783
Autor:
Riley Kahan, BS, Nader Abraham, MD, Min Zhang, MD, Valery Novokhatny, PhD, Isaac Alderete, BS, Paul Cray, PhD, Fengming Chen, MD, PhD, Qimeng Gao, MD, Greta Cywinska, BS, Ryan Neill, Kentaro Nakata, MD, PhD, Ahmed Hassan, MD, Caroline Rush, BS, Jude Penaflor, BS, Justin J. Pollara, PhD, Matthew G. Hartwig, MD, Benjamin Hughes, PhD, Andrew S. Barbas, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 8, p e1665 (2024)
Background. The clinical success of liver transplantation has led to increased demand, requiring further expansion of the donor pool. Therapeutic interventions to optimize organs from donation after circulatory death (DCD) have significant potential
Externí odkaz:
https://doaj.org/article/198c4a09b7c04981b262f3cc59270a46
Autor:
Ffion R Hammond, Amy Lewis, Gabriele Pollara, Gillian S Tomlinson, Mahdad Noursadeghi, Endre Kiss-Toth, Philip M Elks
Publikováno v:
eLife, Vol 13 (2024)
Tuberculosis is a major global health problem and is one of the top 10 causes of death worldwide. There is a pressing need for new treatments that circumvent emerging antibiotic resistance. Mycobacterium tuberculosis parasitises macrophages, reprogra
Externí odkaz:
https://doaj.org/article/bd3dd043b8a54eb0866c183d509594af
Autor:
Andi Nuredini, Dario Bottignole, Filippo Stragliati, Pietro Anceschi, Sonia Romano, Irene Pollara, Anna Abramo, Francesco Rausa, Liborio Parrino, Lucia Zinno, Carlotta Mutti
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32250- (2024)
The timely introduction of non-invasive ventilation (NIV) is extremely relevant in the multidisciplinary management of patients affected by amyotrophic lateral sclerosis (ALS) and is based on the proper identification of red flags for early diaphragm
Externí odkaz:
https://doaj.org/article/f4d13f85260847918ad17c8094d98c90
Autor:
Danielle Nettere, Shakthi Unnithan, Nicole Rodgers, Junsuke Nohara, Paul Cray, Madison Berry, Caroline Jones, Lawrence Armand, Shuk Hang Li, Stella J. Berendam, Genevieve G. Fouda, Derek W. Cain, Taylor N. Spence, Joshua A. Granek, Clemontina A. Davenport, Robert J. Edwards, Kevin Wiehe, Koen K. A. Van Rompay, M. Anthony Moody, Sallie R. Permar, Justin Pollara
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract An effective HIV-1 vaccine remains a critical unmet need for ending the AIDS epidemic. Vaccine trials conducted to date have suggested the need to increase the durability and functionality of vaccine-elicited antibodies to improve efficacy.
Externí odkaz:
https://doaj.org/article/47723f7571494d1382df246f734a90c6
Autor:
Andrew Ekii Obuku, Jacqueline Kyosiimire Lugemwa, Andrew Abaasa, Moses Joloba, Song Ding, Justin Pollara, Guido Ferrari, Alexandre Harari, Giuseppe Pantaleo, Pontiano Kaleebu
Publikováno v:
BMC Immunology, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Fishing communities surrounding Lake Victoria in Uganda have HIV prevalence of 28% and incidence rates of 5 per 100 person years. More than 50% of the local fishermen are infected with Schistosoma mansoni (S. mansoni). We investig
Externí odkaz:
https://doaj.org/article/6358571b30e84dd4b625aa21047ea98e
Autor:
Haleigh E. Conley, Max M. He, David Easterhoff, Hélène Fradin Kirshner, Sarah L. Cocklin, Jacob Meyer, Taylor Hoxie, Madison Berry, Todd Bradley, William D. Tolbert, Marzena Pazgier, Georgia D. Tomaras, Joern E. Schmitz, Michael Anthony Moody, Kevin Wiehe, Justin Pollara
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Fcγ receptors (FcγRs) are membrane-bound glycoproteins that bind to the fragment crystallizable (Fc) constant regions of IgG antibodies. Interactions between IgG immune complexes and FcγRs can initiate signal transduction that mediates important c
Externí odkaz:
https://doaj.org/article/7ca88bbcf7974541b140d919d5470520
Autor:
Marina Tuyishime, Rachel L. Spreng, Brady Hueber, Junsuke Nohara, Derrick Goodman, Cliburn Chan, Richard Barfield, Whitney E. Beck, Shalini Jha, Stephanie Asdell, Kevin Wiehe, Max M. He, David Easterhoff, Haleigh E. Conley, Taylor Hoxie, Thaddeus Gurley, Caroline Jones, Nihar Deb Adhikary, Francois Villinger, Rasmi Thomas, Thomas N. Denny, Michael Anthony Moody, Georgia D. Tomaras, Justin Pollara, R. Keith Reeves, Guido Ferrari
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Rhesus macaques (RMs) are a common pre-clinical model used to test HIV vaccine efficacy and passive immunization strategies. Yet, it remains unclear to what extent the Fc-Fc receptor (FcR) interactions impacting antiviral activities of antibodies in
Externí odkaz:
https://doaj.org/article/b7b3507768fa4c4a8fd48081695cfafd