Výsledky vyhledávání - "Polito, Letizia"

Report

Applying the Estimand and Target Trial frameworks to external control analyses using observational data: a case study in the solid tumor setting

Autor: Polito, Letizia, Liang, Qixing, Pal, Navdeep, Mpofu, Philani, Sawas, Ahmed, Humblet, Olivier, Rufibach, Kaspar, Heinzmann, Dominik

In causal inference, the correct formulation of the scientific question of interest is a crucial step. Here we apply the estimand framework to a comparison of the outcomes of patient-level clinical trials and observational data to help structure the

Externí odkaz: http://arxiv.org/abs/2208.06707

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Akademický článek

Real-World Comparative Effectiveness of First-Line Alectinib Versus Crizotinib in Patients With Advanced ALK-Positive NSCLC With or Without Baseline Central Nervous System Metastases

Autor: Zhang, Qing, Lin, Jessica J., Pal, Navdeep, Polito, Letizia, Trinh, Huong, Hilton, Magalie, Smoljanović, Vlatka, Kurtsikidze, Nino, Archer, Venice, Krebs, Matthew G.

Publikováno v: In JTO Clinical and Research Reports April 2023 4(4)

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Akademický článek

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Dissertation/ Thesis

Genetic and environmental factors affecting Alzheimer's disease pathogenic mechanism : role of sirtuins

Autor: Polito, Letizia

Alzheimer's disease (AD) is the leading cause of senile dementia and the current lack of effective treatments provides a strong incentive for an improved therapeutic strategy. In particular, non-pharmacological treatments, such as calorie restriction

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551608

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