Discovery and Verification of Extracellular miRNA Biomarkers for Non-invasive Prediction of Pre-eclampsia in Asymptomatic Women

Autor: Srinivasan, Srimeenakshi, Treacy, Ryan, Herrero, Tiffany, Olsen, Richelle, Leonardo, Trevor R, Zhang, Xuan, DeHoff, Peter, To, Cuong, Poling, Lara G, Fernando, Aileen, Leon-Garcia, Sandra, Knepper, Katharine, Tran, Vy, Meads, Morgan, Tasarz, Jennifer, Vuppala, Aishwarya, Park, Soojin, Laurent, Clara D, Bui, Tony, Cheah, Pike See, Overcash, Rachael Tabitha, Ramos, Gladys A, Roeder, Hilary, Ghiran, Ionita, Parast, Mana, PAPR Study Consortium, Breakefield, Xandra O, Lueth, Amir J, Rust, Sharon R, Dufford, Max T, Fox, Angela C, Hickok, Durlin E, Burchard, Julja, Boniface, J Jay, Laurent, Louise C

Publikováno v: Cell reports. Medicine, vol 1, iss 2

Development of effective prevention and treatment strategies for pre-eclampsia is limited by the lack of accurate methods for identification of at-risk pregnancies. We performed small RNA sequencing (RNA-seq) of maternal serum extracellular RNAs (exR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::28f0b39b39be62dbeab4a49f52e82d53
https://escholarship.org/uc/item/47d6756m

Discovery and Verification of Extracellular miRNA Biomarkers for Non-invasive Prediction of Pre-eclampsia in Asymptomatic Women.

Autor: Srinivasan S; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA.; These authors contributed equally., Treacy R; Sera Prognostics, 2749 East Parleys Way, Salt Lake City, UT 84109, USA.; These authors contributed equally., Herrero T; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA.; Department of Obstetrics and Gynecology, Stanford University, Palo Alto, CA 94305, USA.; These authors contributed equally., Olsen R; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA.; Franciscan Maternal-Fetal Medicine Associates at St. Joseph, Tacoma, WA 98405, USA., Leonardo TR; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA.; Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL 60607, USA., Zhang X; Neurology and Radiology Services and Program in Neuroscience, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02115, USA., DeHoff P; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., To C; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Poling LG; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Fernando A; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Leon-Garcia S; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Knepper K; Department of Pathology, University of California, San Diego, La Jolla, CA 92037, USA., Tran V; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Meads M; Department of Pathology, University of California, San Diego, La Jolla, CA 92037, USA., Tasarz J; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Vuppala A; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Park S; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Laurent CD; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Bui T; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Cheah PS; Neurology and Radiology Services and Program in Neuroscience, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02115, USA.; Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia., Overcash RT; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Ramos GA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA., Roeder H; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA.; Kaiser Permanente San Diego, San Diego, CA 92120, USA., Ghiran I; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA., Parast M; Department of Pathology, University of California, San Diego, La Jolla, CA 92037, USA., Breakefield XO; Neurology and Radiology Services and Program in Neuroscience, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02115, USA., Lueth AJ; Sera Prognostics, 2749 East Parleys Way, Salt Lake City, UT 84109, USA., Rust SR; Sera Prognostics, 2749 East Parleys Way, Salt Lake City, UT 84109, USA., Dufford MT; Sera Prognostics, 2749 East Parleys Way, Salt Lake City, UT 84109, USA., Fox AC; Sera Prognostics, 2749 East Parleys Way, Salt Lake City, UT 84109, USA., Hickok DE; Sera Prognostics, 2749 East Parleys Way, Salt Lake City, UT 84109, USA., Burchard J; Sera Prognostics, 2749 East Parleys Way, Salt Lake City, UT 84109, USA., Boniface JJ; Sera Prognostics, 2749 East Parleys Way, Salt Lake City, UT 84109, USA., Laurent LC; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA 92037, USA.; Lead Contact.

Publikováno v: Cell reports. Medicine [Cell Rep Med] 2020 May 19; Vol. 1 (2).