Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Polina Selkova"'
Autor:
Maksim Kazalov, Mikhail Khodorkovskii, Anatolii Arseniev, Polina Selkova, Sergey Shmakov, T. O. Artamonova, Aleksandra Vasileva, Daria Artamonova, Olga Musharova, Ignatiy Goryanin, Tatyana Zyubko, Konstantin Severinov, Iana Fedorova, Georgii Pobegalov, Marina Abramova
Publikováno v:
Nucleic Acids Research
CRISPR-Cas defense systems opened up the field of genome editing due to the ease with which effector Cas nucleases can be programmed with guide RNAs to access desirable genomic sites. Type II-A SpCas9 from Streptococcus pyogenes was the first Cas9 nu
Position of Deltaproteobacteria Cas12e nuclease cleavage sites depends on spacer length of guide RNA
Autor:
Maksim Kazalov, Konstantin Severinov, Nataliia Shcheglova, Aleksandra Vasileva, Polina Selkova, T. O. Artamonova, Iana Fedorova, Tatyana Zyubko, Anatolii Arseniev, Georgii Pobegalov, Olga Musharova, Mikhail Khodorkovskii
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Cas12e proteins (formerly CasX) form a distinct subtype of Class II type V CRISPR-Cas effectors. Recently, it was shown that DpbCas12e from Deltaproteobacteria and PlmCas12e from Planctomycetes can introduce programmable double-stranded breaks in mam
Autor:
Marina Abramova, Daria Artamonova, Ignatiy Goryanin, Olga Musharova, Mikhail Khodorkovskii, Konstantin Severinov, Sergey Shmakov, Georgii Pobegalov, Polina Selkova, T. O. Artamonova, Tatyana Zyubko, Maksim Kazalov, Aleksandra Vasileva, Anatolii Arseniev, Iana Fedorova
Publikováno v:
Nucleic Acids Research
Type II CRISPR–Cas9 RNA-guided nucleases are widely used for genome engineering. Type II-A SpCas9 protein from Streptococcus pyogenes is the most investigated and highly used enzyme of its class. Nevertheless, it has some drawbacks, including a rel