Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Polina Gervas"'
Autor:
Nataliya Babyshkina, Nataliya Popova, Evgeny Grigoryev, Tatyana Dronova, Polina Gervas, Alexey Dobrodeev, Dmitry Kostromitskiy, Victor Goldberg, Sergei Afanasiev, Nadejda Cherdyntseva
Publikováno v:
Drug Target Insights, Vol 18, Iss 1 (2024)
Immunotherapy has become an integral part of a comprehensive treatment approach to metastatic colorectal cancer (mCRC). Nivolumab (Opdivo) is a human immunoglobulin G4 monoclonal antibody that blocks the interaction between the programmed cell death
Externí odkaz:
https://doaj.org/article/3a8b6f17462045d08f866d5fe967bc4f
Autor:
Polina Gervas, Aleksey Molokov, Nataliya Babyshkina, Artem Kiselev, Aleksei Zarubin, Evgeny Yumov, Lubov Pisareva, Evgeny Choynzonov, Nadezda Cherdyntseva
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 23:2027-2033
Germline alterations in BRCA1, BRCA2, and other genes are responsible for early-onset breast cancer. However, up to 20% of molecular tests report genetic variant of unknown significance (VUS) or novel variants that have never been previously describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1803d7a422bccb1d322a43c4f0ad0db
https://doi.org/10.31557/apjcp.2022.23.6.2027
https://doi.org/10.31557/apjcp.2022.23.6.2027
Publikováno v:
Cytokine & Growth Factor Reviews. 62:62-69
The transforming growth factor beta (TGF-β) signaling pathway plays complex role in the regulation of cell proliferation, apoptosis and differentiation in breast cancer. TGF-β activation can lead to multiple cellular responses mediating the drug re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f586fc8faa8741a5bc2c3f20c24b224
https://doi.org/10.1016/j.cytogfr.2021.09.005
https://doi.org/10.1016/j.cytogfr.2021.09.005
Autor:
Aleksei Zarubin, Evgeny Yumov, Evgeny Choynzonov, Polina Gervas, Artem Kiselev, Nadezda Cherdyntseva, A. Molokov, Lubov Pisareva
Background: Germline alterations in ATM, BRCA1, BRCA2, and other genes are responsible for early-onset breast cancer. However, up to 20% of molecular tests report genetic variant of unknown significance (VUS) or novel variants that have never been pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c51cab9d607377df753e6b01abcb463e
https://doi.org/10.21203/rs.3.rs-783155/v1
https://doi.org/10.21203/rs.3.rs-783155/v1
Autor:
Polina Gervas, N. Cherdyntseva, Elena A. Malinovskaya, Evgeny Choynzonov, Boris Klyuch, Lubov Pisareva, Alexey Molokov, Artem Kiselev, Evgeny Denisov
Publikováno v:
Molecular Biology Reports. 46:5537-5541
To date, there are a limited number of reports on inherited gene mutations associated with breast cancer (BC) among Mongoloid indigenous people in Russia. The present study aimed at identifying the BC-associated genes in 26 Russian Mongoloid BC patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::470e73740f696484829985dc8ad937e9
https://doi.org/10.1007/s11033-019-04928-y
https://doi.org/10.1007/s11033-019-04928-y
Autor:
A Chernyshova, Artem Kiselev, Ye Panferova, Polina Gervas, A. Ivanova, A. Molokov, Lubov Pisareva, N. Cherdyntseva, Evgeny Choynzonov
Publikováno v:
Experimental oncology. 2021. Vol. 43, № 1. P. 52-55
Background In Russia, more than 50,000 women are diagnosed with breast cancer (BC) every year. Russia is a multinational country - about 200 ethnic groups live on its territory. Khakass, Buryats, Tuvans and other ethnic groups show higher rate of inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adaab2e3c7e59d278fa675e1f108c271
https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000902491
https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000902491
Autor:
N. Cherdyntseva, Evgeny Choynzonov, A. Molokov, Polina Gervas, Anastasia A Schegoleva, Artem Kiselev, Lubov Pisareva, Yury Tyukalov, Nataliya Babyshkina
Publikováno v:
Molecular biology reports. 47(7)
In accordance with the Asian BRCA Consortium data, there is a significant difference in incidence rate of breast cancer depending on age, as well as spectrum and prevalence of BRCA1/2 mutations between Mongoloid (East Asian) and Caucasoid (European)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd197ffd6bdbf16b8b2b0e8fbd134d92
https://pubmed.ncbi.nlm.nih.gov/32601921
https://pubmed.ncbi.nlm.nih.gov/32601921
Autor:
E. N. Voropaeva, Vladimir N. Maksimov, N. Cherdyntseva, Evgeny Denisov, Elena A. Malinovskaya, Lubov Pisareva, Evgeny Cherdyntsev, Polina Gervas, Yelena Panferova, Evgeny Choynzonov, Dmitriy Perinov, Michail Voevoda
Publikováno v:
Cancer biomarkers. 2017. Vol. 18, № 3. P. 291-296
Background The BRCA1 mutations that are endemic to the Slavic population of Russia have not been identified among indigenous peoples, including the Buryats, Tuvinians and Altaians with hereditary breast cancer. Objective This study was aimed to ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796fe3f8ecf8f87ba4341a3da514990c
http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000629816
http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000629816
Autor:
F. Ivanova, Nikolai V. Litviakov, Evgeny Cherdyntsev, N. Cherdyntseva, Evgeny Denisov, Polina Gervas
Publikováno v:
AIP Conference Proceedings.
Only 25% of cancer patients, on average, benefit from therapy. Even in the cases of complete clinical response the tumor progression is an event of high level expectation. The main reasons for tumor progression are: intratumor heterogeneity resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbada7c6dce93d5b0d963e6f59cffa2
https://doi.org/10.1063/1.4960229
https://doi.org/10.1063/1.4960229
Autor:
Valentina A. Belyavskaya, Mariia V. Vasileva, Nadejda V. Cherdyntseva, Vladimir V. Klimov, Polina Gervas
Publikováno v:
11.1 Lung Cancer.
Background: Most of population-based studies demonstrate an inverse correlation between allergic diseases and lung cancer. However some studies provide conflicting results. Polymorphisms of genes associated with immune system functions modify lung ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45fe8918d7f0e432bbf61b9ee941fb63
https://doi.org/10.1183/13993003.congress-2015.pa541
https://doi.org/10.1183/13993003.congress-2015.pa541