Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Polina Fenik"'
Autor:
Darrell Eacret, Elisabetta Manduchi, Julia Noreck, Emma Tyner, Polina Fenik, Amelia D. Dunn, Jonathan Schug, Sigrid C. Veasey, Julie A. Blendy
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Disrupted sleep is a symptom of many psychiatric disorders, including substance use disorders. Most drugs of abuse, including opioids, disrupt sleep. However, the extent and consequence of opioid-induced sleep disturbance, especially during
Externí odkaz:
https://doaj.org/article/46e6f3cd581c4b7d935a19695d273593
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Chronic sleep disruption is a risk factor for Alzheimer’s disease (AD), yet mechanisms by which sleep disturbances might promote or exacerbate AD are not understood. Short-term sleep loss acutely increases hippocampal amyloid β (Aβ) in wild type
Externí odkaz:
https://doaj.org/article/529405690df248d6a5d89ca38ce12c18
Autor:
Guanxia Zhan, Sigrid C. Veasey, Polina Fenik, Yan Zhu, Cathy Liu, Jessica E Owen, Patrick Bell
Publikováno v:
Sleep
Chronic short sleep (CSS) is prevalent in modern societies and has been proposed as a risk factor for Alzheimer’s disease (AD). In support, short-term sleep loss acutely increases levels of amyloid β (Aβ) and tau in wild type (WT) mice and humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ca4ebe20400157835e8c6cd261223c
https://doi.org/10.1093/sleep/zsab057
https://doi.org/10.1093/sleep/zsab057
Publikováno v:
Sleep. 45:A135-A135
Introduction Fragmented sleep occurs when there are repetitive, short interruptions of sleep, resulting in less than six hours of sleep per day. Overall, however, in the United States, sleep fragmentation is reported by 30% of employed adults. Sleep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e423ec4e3357e5fcc68d21a5e8f41f
https://doi.org/10.1093/sleep/zsac079.299
https://doi.org/10.1093/sleep/zsac079.299
Autor:
Zachary Zamore, Allison Tzu-Han Chou, Naomi Schifman, Polina Fenik, Keelee Pullum, Michelle Slinger, Sigrid Veasey
Publikováno v:
Sleep. 45:A135-A135
Introduction Sleep deprivation impairs hippocampal-dependent memory, and hippocampal-dependent memory impairments occur in some dementias, including Alzheimer’s disease. As our population continues to age, understanding the molecular basis for memo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e5c44b94d95136f52587a326e7ec56b
https://doi.org/10.1093/sleep/zsac079.298
https://doi.org/10.1093/sleep/zsac079.298
Autor:
Allison Tzu-Han Chou, Henry Hollis, Polina Fenik, Keelee Pullum, Michelle Slinger, Zachary Zamore, Yan Zhu, Ron Anafi, Sigrid Veasey
Publikováno v:
Sleep. 45:A130-A130
Introduction Chronic sleep disruption (CSD) in young adult mice leads to phenotypes consistent with early (pre-plaque) Alzheimer’s Disease (AD), including increased Aβ and hippocampal neuron loss. Mechanisms underlying this injury are not known. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ff0b5b7c6235de18817251e3af0f22
https://doi.org/10.1093/sleep/zsac079.286
https://doi.org/10.1093/sleep/zsac079.286
Autor:
Madison Brandes, Noelle Francois, Guanxia Zhan, Sigrid C. Veasey, Yan Zhu, Polina Fenik, Katherine Shulman, Patrick Bell
Publikováno v:
The Journal of Neuroscience
Brainstem locus ceruleus neurons (LCn) are among the first neurons across the lifespan to evidence tau pathology, and LCn are implicated in tau propagation throughout the cortices. Yet, events influencing LCn tau are poorly understood. Activated pers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877d07df55c9e6b18c532cf16613f766
https://doi.org/10.1523/jneurosci.0275-18.2018
https://doi.org/10.1523/jneurosci.0275-18.2018
Publikováno v:
Sleep. 42:A120-A121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0495de28ac2a4ba7cf2f784cac9209d4
https://doi.org/10.1093/sleep/zsz067.294
https://doi.org/10.1093/sleep/zsz067.294
Autor:
Jing Zhang, Maxime M. Wang, Guanxia Zhan, Sigrid C. Veasey, Shayla Reid, Yan Zhu, James G. Davis, Joseph A. Baur, Lori Panossian, David Lai, Polina Fenik
Publikováno v:
The Journal of Neuroscience. 34:4418-4431
Modern society enables a shortening of sleep times, yet long-term consequences of extended wakefulness on the brain are largely unknown. Essential for optimal alertness, locus ceruleus neurons (LCns) are metabolically active neurons that fire at incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d06bddf9b9487c3bec8766c62b7150
https://doi.org/10.1523/jneurosci.5025-12.2014
https://doi.org/10.1523/jneurosci.5025-12.2014
Autor:
Guanxia Zhan, Sigrid C. Veasey, David A. Piel, Yanpeng Li, Lori Panossian, Sheryl G. Beck, Seema Bhatnagar, Yan Zhu, Yu-Ting Chou, Jing Zhang, Polina Fenik
Publikováno v:
Sleep. 37:51-64
STUDY OBJECTIVES Delayed hypercapnic arousals may occur in obstructive sleep apnea. The impaired arousal response is expected to promote more pronounced oxyhemoglobin desaturations. We hypothesized that long-term sleep fragmentation (SF) results in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68e412d87032569a80cdf8825a075ac
https://doi.org/10.5665/sleep.3306
https://doi.org/10.5665/sleep.3306