Genetic variants of CTLA4 are associated with clinical outcome of patients with multiple myeloma

Autor: Yolanda Gonzalez-Montes, Rocío Rodriguez-Romanos, Alicia Villavicencio, Gemma Osca-Gelis, Marta González-Bártulos, Francesca Llopis, Victòria Clapes, Albert Oriol, Anna Sureda, Lourdes Escoda, Josep Sarrà, Ana Garzó, Natàlia Lloveras, Isabel Díez, Isabel Granada, David Gallardo

Immune dysfunction in patients with multiple myeloma (MM) affects both the innate and adaptive immune system. Molecules involved in the immune checkpoint pathways are essential to determine the ability of cancer cells to escape from the immune system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3948a843c8c0efaafd73f4a053084489
http://hdl.handle.net/2445/198590

Contribution of TEX15 genetic variants to the risk of developing severe non-obstructive oligozoospermia

Autor: Guzmán Jiménez, Andrea, González Muñoz, Sara, Cerván Martín, Miriam, Rivera Egea, Rocío, Garrido, Nicolás, Luján, Saturnino, Santos Ribeiro, Samuel, Castilla, José A., Gonzalvo, M. Carmen, Clavero, Ana, Vicente, F. Javier, Maldonado, Vicente, Villegas Salmerón, Javier, Burgos, Miguel, Jiménez, Rafael, Pinto, Maria Graça, Pereira, Isabel, Nunes, Joaquim, Sánchez Curbelo, Josvany, López Rodrigo, Olga, Pereira Caetano, Iris, Marques, Patricia Isabel, Carvalho, Filipa, Barros, Alberto, Bassas, Lluís, Seixas, Susana, Gonçalves, João, Lopes, Alexandra M., Larriba, Sara, Palomino Morales, Rogelio J., Carmona, F. David, Bossini Castillo, Lara, Ivirma Group, Lisbon Clinical Group

Publikováno v: Frontiers in Cell and Developmental Biology. 10

Background: Severe spermatogenic failure (SPGF) represents one of the most relevant causes of male infertility. This pathological condition can lead to extreme abnormalities in the seminal sperm count, such as severe oligozoospermia (SO) or non-obstr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b7501d464c760838a24932cde60bb9
https://doi.org/10.3389/fcell.2022.1089782

Multi-ancestry genome-wide association study of asthma exacerbations

Autor: Herrera Luis, Esther, Ortega, Victor E., Ampleford, Elizabeth J., Sio, Yang Yie, Granell, Raquel, de Roos, Emmely, Terzikhan, Natalie, Elorduy Vergara, Ernesto, Hernández Pacheco, Natalia, Pérez García, Javier, Martín González, Elena, Lorenzo Díaz, Fabián, Hashimoto, Simone, Brinkman, Paul, U-BIOPRED Study Group, Jorgensen, Andrea L., Yan, Qi, Forno, Erick, Vijverberg, Susanne J., Lethem, Ryan, Espuela Ortiz, Antonio, Gorenjak, Mario, Eng, Celeste, González Pérez, Ruperto, Hernández Pérez, José M., Poza Guedes, Paloma, Sardón Prado, Olaia, Corcuera Elosegui, Paula, Hawkins, Greg A., Marsico, Annalisa, Bahmer, Thomas, Rabe, Klaus F., Hansen, Gesine, Kopp, Matthias Volkmar, Rios, Raimon, Cruz Carmona, María Jesús, González Barcala, Francisco Javier, Olaguibel, José María, Plaza, Vicente, Quirce, Santiago, Canino, Glorisa, Cloutier, Michelle, Del Pozo, Victoria, Rodríguez Santana, José R., Korta Murua, José Javier, Villar, Jesús, Potočnik, Uroš, Figueiredo, Camila, Kabesch, Michael, Mukhopadhyay, Somnath, Pirmohamed, Munir, Hawcutt, Daniel B., Melén, Erik, Palmer, Colin N., Turner, Steven, Maitland-van der Zee, Anke H., von Mutius, Erika, Celedón, Juan C., Brusselle, Guy, Chew, Fook Tim, Bleecker, Eugene, Meyers, Deborah, Burchard, Esteban G., Pino Yanes, María

Publikováno v: Herrera-Luis, E, Ortega, V, Ampleford, E, Sio, Y Y, Granell, R, Lethem, R, Pino-Yanes, M & et, A 2022, ' Multi-ancestry genome-wide association study of asthma exacerbations ', Pediatric Allergy and Immunology, vol. 33, no. 6, e13802 . https://doi.org/10.1111/pai.13802
Addi. Archivo Digital para la Docencia y la Investigación
instname
Pediatric Allergy and Immunology, 33(6):e13802. Blackwell Publishing
Pediatr. Allergy Immunol. 33:e13802 (2022)
PEDIATRIC ALLERGY AND IMMUNOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Scientia
Herrera-Luis, Esther; Ortega, Victor E; Ampleford, Elizabeth J; Sio, Yang Yie; Granell, Raquel; de Roos, Emmely; Terzikhan, Natalie; Vergara, Ernesto Elorduy; Hernandez-Pacheco, Natalia; Perez-Garcia, Javier; Martin-Gonzalez, Elena; Lorenzo-Diaz, Fabian; Hashimoto, Simone; Brinkman, Paul; Jorgensen, Andrea L; Yan, Qi; Forno, Erick; Vijverberg, Susanne J; Lethem, Ryan; Espuela-Ortiz, Antonio; ... (2022). Multi-ancestry genome-wide association study of asthma exacerbations. Pediatric allergy and immunology, 33(6), e13802. Wiley-Blackwell 10.1111/pai.13802
Pediatr Allergy Immunol
Pediatric allergy and immunology, 33(6):e13802. Blackwell Munksgaard

Background: Asthma exacerbations are a serious public health concern due to high healthcare resource utilization, work/school productivity loss, impact on quality of life, and risk of mortality. The genetic basis of asthma exacerbations has been stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a36b2940a1b9606b47e851a2c57a5c
https://hdl.handle.net/1983/3527f915-59cc-4a55-aae9-17f281e40243

Influence of Type 2 Diabetes in the Association of PNPLA3 rs738409 and TM6SF2 rs58542926 Polymorphisms in NASH Advanced Liver Fibrosis

Autor: Pablo Gabriel-Medina, Roser Ferrer-Costa, Francisco Rodriguez-Frias, Andreea Ciudin, Salvador Augustin, Jesus Rivera-Esteban, Juan M. Pericàs, David Martinez Selva

Publikováno v: Biomedicines; Volume 10; Issue 5; Pages: 1015
Scientia

Advanced fibrosis; Nonalcoholic steatohepatitis; Type 2 diabetes Fibrosis avanzada; Esteatohepatitis no alcohólica; Diabetes tipo 2 Fibrosi avançada; Esteatohepatitis no alcohòlica; Diabetis tipus 2 Nonalcoholic steatohepatitis (NASH) is a leading

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc4f5f6805b36adee91fcbb8d56762f

Gene variation at immunomodulatory and cell adhesion molecules Loci impacts primary Sjögren's Syndrome

Autor: Sergi Casadó-Llombart, Hoda Gheitasi, Silvia Ariño, Marta Consuegra-Fernández, Noelia Armiger-Borràs, Belchin Kostov, Manuel Ramos-Casals, Pilar Brito-Zerón, Francisco Lozano

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)

Primary Sjögren's syndrome (pSS) is an autoimmune disease triggered by a combination of environmental and host genetic factors, which results in the focal lymphocytic infiltration of exocrine glands causing eye and mouth dryness. Glandular infiltrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6998e5aa0d5085f73ff3e2ffff03f74
https://hdl.handle.net/2117/371513