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Exposure–response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial

Autor: Takayuki Yoshino, Ling Yang, Pilar García-Alfonso, Allen Lee Cohn, Philip Clingan, F. Nasroulah, Jonathon Polikoff, Volker Heinemann, Lisa O’Brien, Eric Van Cutsem, David Craig Portnoy, Kentaro Yamazaki, Jana Prausová, Rocio Garcia-Carbonero, Josep Tabernero, György Bodoky, Tudor Ciuleanu, Ling Gao, David Ferry, Sara Lonardi, Radka Obermannova

Publikováno v: Cancer Chemotherapy and Pharmacology
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Purpose To characterize ramucirumab exposure–response relationships for efficacy and safety in patients with metastatic colorectal cancer (mCRC) using data from the RAISE study. Methods Sparse pharmacokinetic samples were collected; a population ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ae755a5849ab8f5cceec01e6bdf5de
http://europepmc.org/articles/PMC5573752