Mitohormesis during advanced stages of Duchenne muscular dystrophy reveals a redox-sensitive creatine pathway that can be enhanced by the mitochondrial-targeting peptide SBT-20.

Autor: Hughes MC; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada. Electronic address: hughesmeghanc@gmail.com., Ramos SV; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada. Electronic address: sofhia.ramos@adventhealth.com., Brahmbhatt AN; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada. Electronic address: anbrahm4@yorku.ca., Turnbull PC; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada. Electronic address: patrick.c.turnbull@gmail.com., Polidovitch NN; Department of Biology and the Muscle Health Research Centre, York University, Toronto, ON, Canada. Electronic address: n.polidovitch@gmail.com., Garibotti MC; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada. Electronic address: mgarib@yorku.ca., Schlattner U; University Grenoble Alpes, Inserm U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and Institut Universitaire de France, Grenoble, France. Electronic address: uwe.schlattner@univ-grenoble-alpes.fr., Hawke TJ; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada. Electronic address: hawke@mcmaster.ca., Simpson JA; Department of Human Health and Nutritional Sciences and Cardiovascular Research Group, University of Guelph, Guelph, ON, Canada; IMPART Team Canada Investigator Network, Saint John, New Brunswick, Canada. Electronic address: jeremys@uoguelph.ca., Backx PH; Department of Biology and the Muscle Health Research Centre, York University, Toronto, ON, Canada. Electronic address: pbackx@yorku.ca., Perry CG; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada. Electronic address: cperry@yorku.ca.

Publikováno v: Redox biology [Redox Biol] 2024 Oct; Vol. 76, pp. 103319. Date of Electronic Publication: 2024 Aug 20.