Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Poliany G. Freitas"'
Autor:
Maria Eliza de Castro Moreira, Eliana Carla Gomes de Souza, Hilário Cuquetto Mantovani, Hércia Stampini Duarte Martino, Fernanda de Oliveira Araújo, Renata Celi Lopes Toledo, Marcia Paranho Veloso, Andressa Rodrigues de Sousa, Cássio Furtado Lima, Marcelo Henrique dos Santos, Poliany G. Freitas
Publikováno v:
Food Research International. 122:199-208
The objective of this study was to evaluate the effects of an ethanolic extract of the bark of bacupari (Garcinia brasiliensis - EEB) on the abundance of intestinal microbiota, concentration of short-chain fatty acids (SCFAs), oxidative stress, and i
Autor:
Levy Bueno Alves, Rossimiriam Pereira de Freitas, Marcia Paranho Veloso, Patrícia Ferreira Espuri, Vanessa Silva Gontijo, Poliany G. Freitas, Juliana Barbosa Nunes, Rosemeire B. Alves, Marcos José Marques, Fabio Antonio Colombo
Publikováno v:
Experimental parasitology.
The failures in the treatment of leishmaniasis is an increasing problem around the world, especially related to resistance. Thus, we describe the synthesis and in vivo anti-Leishmania activity of alkylphosphocholine and alkyltriazoles; besides, their
Autor:
A. L. F. Arêas, Leonardo B Federico, B. A. Verde, Poliany G. Freitas, A. L. Pascoini, Ihosvany Camps
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 37:1007-1021
In this work, we made use of fragment-based drug design (FBDD) and de novo design to obtain more powerful acetylcholinesterase (AChE) inhibitors. AChE is associated with Alzheimer's disease (AD). It was found that the cholinergic pathways in the cere
Autor:
Daniel de Queiroz Omote, Helen Andrade Arcuri, Icaro Alves Pinto, Thiago C. Elias, Arlindo L. Oliveira, Luciano T. Costa, Tati Ishikawa, Paulo V. S. D. de Carvalho, Walter Filgueira de Azevedo Junior, Susana Vinga, Poliany G. Freitas, Nelson José Freitas da Silveira, Ihosvany Camps
Publikováno v:
Freitas, P G, Elias, T C, Pinto, I A, Costa, L T, de Carvalho, P V S D, Omote, D D Q, Camps, I, Ishikawa, T, Arcuri, H A, Vinga, S, Oliveira, A L, Junior, W F A & da Silveira, N J F 2018, ' Computational approach to the discovery of phytochemical molecules with therapeutic potential targets to the PKCZ protein ', Letters in Drug Design & Discovery, vol. 15, no. 5, pp. 488-499 . https://doi.org/10.2174/1570180814666170810120150
Letters in Drug Design & Discovery
Letters in Drug Design & Discovery
Background: Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignancies in humans and the average 5-year survival rate is one of the lowest among aggressive cancers. Protein kinase C zeta (PKCZ) is highly expressed in head an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1daea79f45d4d1a817b9df2cec5e1801
https://portal.findresearcher.sdu.dk/da/publications/03ebd5d7-a7a0-4bbf-af29-3dca1b3ae9b9
https://portal.findresearcher.sdu.dk/da/publications/03ebd5d7-a7a0-4bbf-af29-3dca1b3ae9b9
Autor:
Marcia Paranho Veloso, Camila de Morais Coelho, Thiago dos Santos, Poliany G. Freitas, Nelson José Freitas da Silveira, Juliana Barbosa Nunes, Camila G. D. Padovani, Wagner Alves de Souza Judice, Diogo Teixeira Carvalho, Marcos José Marques, Ihosvany Camps
Publikováno v:
Journal of the Brazilian Chemical Society, Volume: 29, Issue: 4, Pages: 715-728, Published: APR 2018
Journal of the Brazilian Chemical Society v.29 n.4 2018
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society v.29 n.4 2018
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Leishmaniasis is a neglected pathology with a high incidence worldwide, and is a governmental health issue due to the increased morbidity and mortality associated with the disease and a scarce therapeutic arsenal. Cysteine proteases have been investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ec21c36d60e7a50156be6ad5bef5e1
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532018000400715&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532018000400715&lng=en&tlng=en
Autor:
Cláudio Viegas Junior, Letícia de Almeida, Marcelo Henrique dos Santos, Thiago Elias Castilho, Marcos José Marques, Luciano T. Costa, Poliany G. Freitas, Claudia Mara Maciel-Rezende, Nelson José Freitas da Silveira
Publikováno v:
Journal of the Brazilian Chemical Society v.29 n.3 2018
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 29, Issue: 3, Pages: 515-527, Published: MAR 2018
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 29, Issue: 3, Pages: 515-527, Published: MAR 2018
This study investigates the mechanisms of interaction between benzophenone derivatives and cruzain and Llacys1 (the protein expressed by cysteine protease gene isoform 1 of L. amazonensis) by homology modelling, docking and molecular dynamics simulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fae45c6a58c860453ad69c36d66f2cb
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532018000300515
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532018000300515
Autor:
Lucas Andrade Saraiva, A.F. Barbosa, Marcia Paranho Veloso, J.M. Schneedorf, N.J.F. da Silveira, Poliany G. Freitas, Ihosvany Camps, Marcelo Henrique dos Santos
Publikováno v:
Journal of Luminescence. 132:3027-3034
The binding interaction between mangiferin (MGF), which a natural xanthone isolated from mangoes, and bovine serum albumin (BSA) was studied with absorbance and fluorescence spectroscopy, cyclic voltammetry and molecular modeling. The data were analy