Výsledky vyhledávání - "Polani B, Seshagiri"

Molecular regulators of human blastocyst development and hatching: Their significance in implantation and pregnancy outcome

Autor: Venkatappa, Vani, Satya S, Vasan, Satish K, Adiga, Samson Roy, Varsha, Polani B, Seshagiri

Publikováno v: American Journal of Reproductive Immunology. 89

In humans, blastocyst hatching and implantation events are two sequential, critically linked and rate-limiting events for a prospective pregnancy. These events are regulated by embryo-endometrium derived molecular factors which include hormones, grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49581b330345595471ceb8a181c832d
https://doi.org/10.1111/aji.13635

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Adenosine deaminase modulates metabolic remodeling and orchestrates joint destruction in rheumatoid arthritis

Autor: Venketesh Sivaramakrishnan, Rahul Ray, Saibharath Simha Reddy Santha, Sai Krishna Srimadh Bhagavatham, Polani B. Seshagiri, Vishnu Kannan, Sujith Kumar Pulukool, Narsimulu Gumdal, Divya Sridharan, Sai Mangala Divi, Ashish Pargaonkar, Damodaram Potikuri, Ashwin Ashok Naik, Prakash Khanchandani, K. Narasimhan, Rajesh Babu Dandamudi

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-22 (2021)
Scientific Reports

Rheumatoid Arthritis (RA) is a chronic autoimmune disease associated with inflammation and joint remodeling. Adenosine deaminase (ADA), a risk factor in RA, degrades adenosine, an anti-inflammatory molecule, resulting in an inflammatory bias. We pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de47632cfd94ed92ba9aaa495367f5b2
https://doaj.org/article/dd8e8a9f1ef24cb9976f5b984cc75f22

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Research on early mammalian development in India

Autor: Polani B. Seshagiri, Venkatappa Vani

Publikováno v: The International Journal of Developmental Biology. 64:109-121

Historically, research in India on early mammalian development had only begun, rather modestly, in the last century, unlike the USA and UK. In India, initial studies were on gonadal and reproductive tissue development and function and they were limit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ae6f8ed5a3575dc2f9a7ebd7c5e048
https://doi.org/10.1387/ijdb.190189ps

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Soluble human leukocyte antigen‐G is a potential embryo viability biomarker and a positive predictor of live‐births in humans

Autor: Geetanjali Sachdeva, Satya S. Vasan, Venkatappa Vani, Samson Roy Varsha, Pratap Kumar, Satish Kumar Adiga, Polani B. Seshagiri

Publikováno v: American Journal of Reproductive Immunology. 86

PROBLEM Human infertility affects 15-20% of reproductive-age couples and it is mitigated by assisted reproductive technology (ART) approaches. Poor biological viability of embryos contributes to implantation failure and live birth rate (LBR). This st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034ce0d7959c8e58280b4a0a99a46872
https://doi.org/10.1111/aji.13499

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P–172 Data-independent acquisition-proteomics of human embryo-spent medium and identification of potential embryo biomarkers

Autor: S R Varsha, C Narayana, K Prasad, V Venkatappa, Geetanjali Sachdeva, S S Vasan, Madhulika Pathak, Satish Kumar Adiga, Polani B. Seshagiri

Publikováno v: Human Reproduction. 36

Study question Can human embryo-derived protein(s) serve as viability biomarkers to predict pregnancy outcome, post embryo transfer? Summary answer The human embryo-spent medium proteome, using data-independent acquisition (DIA) approach, could ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa0c0f4197f604262024a031bae04a9f
https://doi.org/10.1093/humrep/deab130.171

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P–258 Ubiquitin, in the human embryo secretome, is a biomarker for embryo viability: a potential predictor of live-births, post embryo transfer

Autor: S S Vasan, V Prata. Kumar, Geetanjali Sachdeva, Polani B. Seshagiri, Satish Kumar Adiga, V Venkatappa, S R Varsha

Publikováno v: Human Reproduction. 36

Study question Whether embryo-secreted ubiquitin could serve as a predictive biomarker for embryo development and viability for assessing pregnancy outcome? Summary answer Embryo-secreted ubiquitin concentrations showed positive correlations with (a)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f06624d0e9d2dbe93ad4882fa3bd648f
https://doi.org/10.1093/humrep/deab130.257

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Successful Derivation of an Induced Pluripotent Stem Cell Line from a Genetically Nonpermissive Enhanced Green Fluorescent Protein-Transgenic FVB/N Mouse Strain

Autor: Polani B. Seshagiri, Darshan S. Chandrashekar, Deepti Abbey, Gurbind Singh, Kshitish K. Acharya, Suchitra Derebail, Isha Verma, Udaykumar Kolkundkar, Mohan C. Vemuri

Publikováno v: Cellular Reprogramming. 21:270-284

The embryonic stem cell line derivation from nonpermissive mouse strains is a challenging and highly inefficient process. The cellular reprogramming strategy provides an alternative route for generating pluripotent stem cell (PSC) lines from such str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdf47240fa92fcd0bc46848645cb544
https://doi.org/10.1089/cell.2019.0019

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Expression and function of interleukin-1β is required for hamster blastocyst hatching: Involvement of hatching-associated cathepsin proteases

Autor: Venkatappa Vani, Polani B. Seshagiri, Madhulika Pathak

Publikováno v: Molecular reproduction and developmentREFERENCES. 88(4)

In mammals, the phenomenon of blastocyst hatching is an essential prerequisite for successful implantation. Blastocyst hatching is regulated by various molecules. Of them, cytokines, expressed by preimplantation embryos, are thought to be functionall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3092696cf182d677cafb9df5c1c1d609
https://pubmed.ncbi.nlm.nih.gov/33719101

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Akademický článek

Endocrine correlates of musth in free-ranging Asian elephants (Elephas maximus) determined by non-invasive faecal steroid hormone metabolite measurements.

Autor: Ratna Ghosal, André Ganswindt, Polani B Seshagiri, Raman Sukumar

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e84787 (2013)

The occurrence of musth, a period of elevated levels of androgens and heightened sexual activity, has been well documented for the male Asian elephant (Elephas maximus). However, the relationship between androgen-dependent musth and adrenocortical fu

Externí odkaz: https://doaj.org/article/2ef629b089724135bfb135cb10cebba8

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