Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Polan T. Santos"'
Autor:
Caitlin E. O’Brien, Polan T. Santos, Ewa Kulikowicz, Jennifer K. Lee, Raymond C. Koehler, Lee J. Martin
Publikováno v:
BMC Neuroscience, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Cardiac arrest (CA) is the most common cause of acute neurologic insult in children. Many survivors have significant neurocognitive deficits at 1 year of recovery. Epoxyeicosatrienoic acids (EETs) are multifunctional endogenous li
Externí odkaz:
https://doaj.org/article/0d46fd1242614ee9bd759802457f0258
Autor:
Caitlin E. O'Brien, Polan T. Santos, Ewa Kulikowicz, Shawn Adams, Jennifer K. Lee, Elizabeth A. Hunt, Raymond C. Koehler, Donald H. Shaffner
Publikováno v:
Resuscitation Plus, Vol 8, Iss , Pp 100174- (2021)
Aim: To evaluate an algorithm that uses an end-tidal carbon dioxide (ETCO2) target of ≥ 30 torr to guide specific changes in chest compression rate and epinephrine administration during cardiopulmonary resuscitation (CPR) in paediatric swine. Metho
Externí odkaz:
https://doaj.org/article/a519e390833d428db0318864d5835f4d
Autor:
Caitlin E. O'Brien, Michael Reyes, Polan T. Santos, Sophia E. Heitmiller, Ewa Kulikowicz, Sapna R. Kudchadkar, Jennifer K. Lee, Elizabeth A. Hunt, Raymond C. Koehler, Donald H. Shaffner
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 19 (2018)
Background The American Heart Association recommends use of physiologic feedback when available to optimize chest compression delivery. We compared hemodynamic parameters during cardiopulmonary resuscitation in which either end‐tidal carbon dioxide
Externí odkaz:
https://doaj.org/article/6746f857bc394c0593e07e46eeea5bb0
Autor:
Polan T. Santos, Caitlin E. O'Brien, May W. Chen, C. Danielle Hopkins, Shawn Adams, Ewa Kulikowicz, Rashmi Singh, Raymond C. Koehler, Lee J. Martin, Jennifer K. Lee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 20 (2018)
Background Neurological deficits in hypoxic‐ischemic encephalopathy, even with therapeutic hypothermia, are partially attributed to white matter injury. We theorized that proteasome insufficiency contributes to white matter injury. Methods and Resu
Externí odkaz:
https://doaj.org/article/dee25330af5e4d3098c46f1298bf20ca
Autor:
Caitlin E O'Brien, Raymond C. Koehler, Shawn Adams, Polan T. Santos, Ewa Kulikowicz, Henry Hardart, Jennifer K. Lee, Lee J. Martin, May W Chen
Publikováno v:
J Neuropathol Exp Neurol
Neonatal hypoxia-ischemia (HI) causes white matter injury that is not fully prevented by therapeutic hypothermia. Adjuvant treatments are needed. We compared myelination in different piglet white matter regions. We then tested whether oleuropein (OLE
Autor:
Polan T. Santos, Qin Qin, Raymond C. Koehler, Dapeng Liu, Peiying Liu, Dengrong Jiang, Erika P. Raven, Shawn Adams, Jennifer K. Lee, Lee J. Martin, Ewa Kulikowicz, Jiangyang Zhang, Aylin Tekes
Publikováno v:
J Magn Reson Imaging
BACKGROUND: Diffusion MRI is routinely used to evaluate brain injury in neonatal encephalopathy. Though abnormal mean diffusivity (MD) is often attributed to cytotoxic edema, the specific contribution from neuronal pathology is unclear. PURPOSE: To d
Autor:
Elizabeth A. Hunt, Shawn Adams, Polan T. Santos, Justin T. Hamrick, Sapna R. Kudchadkar, C. Danielle Hopkins, Caitlin E. O'Brien, Raymond C. Koehler, Donald H. Shaffner, Jennifer K. Lee, Michael Reyes, Ewa Kulikowicz, Jennifer L. Hamrick
Publikováno v:
Resuscitation
AIM: To examine the relationship between survival and diastolic blood pressure (DBP) throughout resuscitation from paediatric asphyxial cardiac arrest. METHODS: Retrospective, secondary analysis of 200 swine resuscitations. Swine underwent asphyxial
Autor:
Shawn Adams, Raymond C. Koehler, Caitlin E. O'Brien, Donald H. Shaffner, Polan T. Santos, Ewa Kulikowicz, Jennifer K. Lee, Elizabeth A. Hunt
Publikováno v:
Resuscitation Plus, Vol 8, Iss, Pp 100174-(2021)
Resuscitation Plus
Resuscitation Plus
Aim: To evaluate an algorithm that uses an end-tidal carbon dioxide (ETCO2) target of ≥ 30 torr to guide specific changes in chest compression rate and epinephrine administration during cardiopulmonary resuscitation (CPR) in paediatric swine. Metho
Autor:
Polan T. Santos, Ewa Kulikowicz, Raymond C. Koehler, May W Chen, Jennifer K. Lee, Lee J. Martin
Publikováno v:
J Neurosci Res
Neonatal hypoxic-ischemic encephalopathy (HIE) causes significant morbidity despite treatment with therapeutic hypothermia. Mitochondrial dysfunction may drive the mechanisms underlying neuronal cell death, thereby making mitochondria prime targets f
Autor:
Ewa Kulikowicz, C. Danielle Hopkins, Michael Reyes, Raymond C. Koehler, Jennifer K. Lee, Elizabeth A. Hunt, Shawn Adams, Caitlin E O'Brien, Donald H. Shaffner, Polan T. Santos
Publikováno v:
Circulation. 140
Introduction: The American Heart Association (AHA) recommends the use of end-tidal CO 2 (ETCO 2 ) to evaluate the quality of chest compression delivery during CPR. In a pediatric model of asphyxial cardiac arrest, ETCO 2 -guided chest compression del