Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pol Garcia-Segura"'
Autor:
Júlia Solana-Balaguer, Pol Garcia-Segura, Genís Campoy-Campos, Almudena Chicote-González, Joaquín Fernández-Irigoyen, Enrique Santamaría, Esther Pérez-Navarro, Mercè Masana, Jordi Alberch, Cristina Malagelada
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Huntington’s disease (HD) is a neurological disorder caused by a CAG expansion in the Huntingtin gene (HTT). HD pathology mostly affects striatal medium-sized spiny neurons and results in an altered cortico-striatal function. Recent studie
Externí odkaz:
https://doaj.org/article/06a7d592cf8441f28e2a2b4412620870
Autor:
Júlia Solana‐Balaguer, Núria Martín‐Flores, Pol Garcia‐Segura, Genís Campoy‐Campos, Leticia Pérez‐Sisqués, Almudena Chicote‐González, Joaquín Fernández‐Irigoyen, Enrique Santamaría, Esther Pérez‐Navarro, Jordi Alberch, Cristina Malagelada
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) play a crucial role in intercellular communication, participating in the paracrine trophic support or in the propagation of toxic molecules, including proteins. RTP801 is a stress‐regulated protein, whose level
Externí odkaz:
https://doaj.org/article/dfb176b0086a47cd9b888eb3c0d1f769
Autor:
Bryan Saldivar-Espinoza, Pol Garcia-Segura, Nil Novau-Ferré, Guillem Macip, Ruben Martínez, Pere Puigbò, Adrià Cereto-Massagué, Gerard Pujadas, Santiago Garcia-Vallve
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9072 (2023)
Mutation research is crucial for detecting and treating SARS-CoV-2 and developing vaccines. Using over 5,300,000 sequences from SARS-CoV-2 genomes and custom Python programs, we analyzed the mutational landscape of SARS-CoV-2. Although almost every n
Externí odkaz:
https://doaj.org/article/19565bebc4264da2b7cb5002625532c2
Autor:
Bryan Saldivar-Espinoza, Guillem Macip, Pol Garcia-Segura, Júlia Mestres-Truyol, Pere Puigbò, Adrià Cereto-Massagué, Gerard Pujadas, Santiago Garcia-Vallve
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14683 (2022)
Predicting SARS-CoV-2 mutations is difficult, but predicting recurrent mutations driven by the host, such as those caused by host deaminases, is feasible. We used machine learning to predict which positions from the SARS-CoV-2 genome will hold a recu
Externí odkaz:
https://doaj.org/article/36e3676b9a2b487cba042326f41b19ef
Autor:
Guillem Macip, Pol Garcia-Segura, Júlia Mestres-Truyol, Bryan Saldivar-Espinoza, Gerard Pujadas, Santiago Garcia-Vallvé
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 259 (2021)
In this review, we collected 1765 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) M-pro inhibitors from the bibliography and other sources, such as the COVID Moonshot project and the ChEMBL database. This set of inhibitors includes only
Externí odkaz:
https://doaj.org/article/01e3a36648dd4a59bfad7fc665dae3e8
Autor:
Cristina Malagelada, Pol Garcia-Segura
Publikováno v:
The FEBS Journal. 290:1735-1739
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d696be938d3f3452e60968e6f84cfd77
https://doi.org/10.1111/febs.16727
https://doi.org/10.1111/febs.16727
Autor:
Júlia Solana-Balaguer, Núria Martín-Flores, Pol Garcia-Segura, Genís Campoy-Campos, Leticia Pérez-Sisqués, Almudena Chicote-González, Joaquín Fernández-Irigoyen, Enrique Santamaría, Esther Pérez-Navarro, Jordi Alberch, Cristina Malagelada
Background Extracellular vesicles (EVs) play a crucial role in intercellular communication, participating in the paracrine trophic support or in the propagation of toxic molecules, including proteins. RTP801 is a stress-regulated protein, whose level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dd9fba49b3c77236d8ec4d7e08b2065
https://doi.org/10.21203/rs.3.rs-2736462/v1
https://doi.org/10.21203/rs.3.rs-2736462/v1
Autor:
Santiago Garcia-Vallve, Bryan Percy Saldivar Espinoza, Gerard Pujadas, Júlia Mestres-Truyol, Guillem Macip, Pol Garcia-Segura
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 259, p 259 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
In this review, we collected 1765 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) M-pro inhibitors from the bibliography and other sources, such as the COVID Moonshot project and the ChEMBL database. This set of inhibitors includes only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a2a507bd4966919df78fcf22dc07cb
https://www.mdpi.com/1422-0067/23/1/259
https://www.mdpi.com/1422-0067/23/1/259
Autor:
Pol Garcia-Segura, María José Ojeda-Montes, Júlia Mestres-Truyol, Gerard Pujadas, Santiago Garcia-Vallvé, Guillem Macip, Adrià Cereto-Massagué, Bryan Saldivar-Espinoza, Aleix Gimeno
Publikováno v:
Medicinal Research Reviews
This review makes a critical evaluation of 61 peer‐reviewed manuscripts that use a docking step in a virtual screening (VS) protocol to predict SARS‐CoV‐2 M‐pro (M‐pro) inhibitors in approved or investigational drugs. Various manuscripts pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ce805143688373c32efe11b88f92ea
https://pubmed.ncbi.nlm.nih.gov/34697818
https://pubmed.ncbi.nlm.nih.gov/34697818