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AI-based histologic scoring enables automated and reproducible assessment of enrollment criteria and endpoints in NASH clinical trials.

Autor: Iyer JS; PathAI, Boston, MA, USA., Pokkalla H; PathAI, Boston, MA, USA., Biddle-Snead C; PathAI, Boston, MA, USA., Carrasco-Zevallos O; PathAI, Boston, MA, USA.; Affiliation shown is that during the time of study; current affiliation is Johnson & Johnson, New Brunswick, NJ, USA., Lin M; PathAI, Boston, MA, USA., Shanis Z; PathAI, Boston, MA, USA., Le Q; PathAI, Boston, MA, USA., Juyal D; PathAI, Boston, MA, USA., Pouryahya M; PathAI, Boston, MA, USA.; Affiliation shown is that during the time of study; current affiliation is AstraZeneca, Gaithersburg, MD, USA., Pedawi A; PathAI, Boston, MA, USA.; Affiliation shown is that during the time of study; current affiliation is Atomwise, San Francisco, CA, USA., Hoffman S; PathAI, Boston, MA, USA., Elliott H; PathAI, Boston, MA, USA.; Affiliation shown is that during the time of study; current affiliation is BigHat Biosciences, San Mateo, CA, USA., Leidal K; PathAI, Boston, MA, USA.; Affiliation shown is that during the time of study; current affiliation is Genesis Therapeutics, Burlingame, CA, USA., Myers RP; Gilead Sciences, Inc., Foster City, CA, USA.; Affiliation shown is that during the time of study; current affiliation is OrsoBio, Inc., Palo Alto, CA, USA., Chung C; Gilead Sciences, Inc., Foster City, CA, USA.; Affiliation shown is that during the time of study; current affiliation is Inipharm, San Diego, CA, USA., Billin AN; Gilead Sciences, Inc., Foster City, CA, USA., Watkins TR; Gilead Sciences, Inc., Foster City, CA, USA., Resnick M; PathAI, Boston, MA, USA.; Affiliation shown is that during the time of study; current affiliation is Rhode Island Hospital and The Miriam Hospital, Providence, RI, USA., Wack K; PathAI, Boston, MA, USA., Glickman J; PathAI, Boston, MA, USA., Burt AD; Newcastle University, Newcastle, UK., Loomba R; NAFLD Research Center, Division of Gastroenterology and Hepatology, University of California at San Diego, San Diego, CA, USA., Sanyal AJ; Stravitz-Sanyal Institute for Liver Disease and Metabolic Health, VCU School of Medicine, Richmond, VA, USA., Montalto MC; PathAI, Boston, MA, USA., Beck AH; PathAI, Boston, MA, USA., Taylor-Weiner A; PathAI, Boston, MA, USA., Wapinski I; PathAI, Boston, MA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Apr 25. Date of Electronic Publication: 2023 Apr 25.