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Collagen IV of basement membranes: II. Emergence of collagen IV ^α345 enabled the assembly of a compact GBM as an ultrafilter in mammalian kidneys.

Autor: Pokidysheva EN; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Aspirnaut, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA. Electronic address: elena.pokidysheva@vumc.org., Redhair N; Aspirnaut, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Ailsworth O; Aspirnaut, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Page-McCaw P; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Rollins-Smith L; Department of Pathology Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Jamwal VS; Mount Desert Island Biological Laboratory, Bar Harbor, Maine, USA., Ohta Y; Department of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, Maryland, USA., Bächinger HP; Research Department, Shriners Hospital for Children, Portland, Oregon, USA., Murawala P; Mount Desert Island Biological Laboratory, Bar Harbor, Maine, USA; Clinic for Kidney and Hypertension Diseases, Hannover Medical School, Hannover, Germany., Flajnik M; Department of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, Maryland, USA., Fogo AB; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Abrahamson D; Department of Cell Biology and Physiology, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas, USA., Hudson JK; Aspirnaut, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Boudko SP; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, USA., Hudson BG; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Aspirnaut, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA; Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 Dec; Vol. 299 (12), pp. 105459. Date of Electronic Publication: 2023 Nov 15.

Collagen IV of basement membranes: I. Origin and diversification of COL4 genes enabling animal evolution.

Autor: Page-McCaw PS, Pokidysheva EN, Darris CE, Chetyrkin S, Fidler AL, Murawala P, Gallup J, Hudson JK, Hudson BG

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 21. Date of Electronic Publication: 2023 Oct 21.

Collagen IV ^α345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture's and Alport diseases.

Autor: Pokidysheva EN; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Seeger H; Nephrology Division, University Hospital Zurich, Zurich, Switzerland., Pedchenko V; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Chetyrkin S; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Bergmann C; Department of Medicine and Nephrology, University Hospital Freiburg, Freiburg, Germany; Medizinische Genetik Mainz, Limbach Genetics, Mainz, Germany., Abrahamson D; Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Cui ZW; Renal Division, Peking University First Hospital, Beijing, PR China., Delpire E; Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Fervenza FC; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA., Fidler AL; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Aspirnaut Program, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Fogo AB; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Gaspert A; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland., Grohmann M; Medizinische Genetik Mainz, Limbach Genetics, Mainz, Germany., Gross O; Clinic of Nephrology and Rheumatology, University Medical Center Goettingen, University of Goettingen, Goettingen, Germany., Haddad G; Nephrology Division, University Hospital Zurich, Zurich, Switzerland., Harris RC; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kashtan C; Division of Pediatric Nephrology, University of Minnesota Medical School and Masonic Children's Hospital, Minneapolis, Minnesota, USA., Kitching AR; Centre for Inflammatory Diseases, Monash University Department Medicine, Nephrology, Monash Health, Clayton, VIC, Australia., Lorenzen JM; Nephrology Division, University Hospital Zurich, Zurich, Switzerland., McAdoo S; Centre for Inflammatory Disease, Imperial College London, London, UK., Pusey CD; Centre for Inflammatory Disease, Imperial College London, London, UK., Segelmark M; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, USA., Simmons A; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Aspirnaut Program, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Voziyan PA; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Wagner T; Medizinische Genetik Mainz, Limbach Genetics, Mainz, Germany., Wüthrich RP; Nephrology Division, University Hospital Zurich, Zurich, Switzerland., Zhao MH; Renal Division, Peking University First Hospital, Beijing, PR China., Boudko SP; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, USA., Kistler AD; Department of Internal Medicine, Kantonsspital Frauenfeld, Frauenfeld, Switzerland., Hudson BG; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Aspirnaut Program, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, USA; Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, USA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA. Electronic address: billy.hudson@vumc.org.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100590. Date of Electronic Publication: 2021 Mar 26.

A chloride ring is an ancient evolutionary innovation mediating the assembly of the collagen IV scaffold of basement membranes.

Autor: Pedchenko V; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Vanderbilt Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232., Bauer R; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Vanderbilt Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232., Pokidysheva EN; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Vanderbilt Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232., Al-Shaer A; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada., Forde NR; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada; Department of Physics, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada., Fidler AL; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Vanderbilt Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Department of AspirnautTM Program, Vanderbilt University Medical Center, Nashville, Tennessee 37232., Hudson BG; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Vanderbilt Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Department of AspirnautTM Program, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37232; Department of Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232; Department of Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232., Boudko SP; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee 37232; Vanderbilt Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232. Electronic address: sergey.budko@vanderbilt.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2019 May 17; Vol. 294 (20), pp. 7968-7981. Date of Electronic Publication: 2019 Mar 28.