Induced proximity of a TIR signaling domain on a plant-mammalian NLR chimera activates defense in plants

Autor: Zane Duxbury, Hailong Guo, Shanshan Wang, Maud Bernoux, Baptiste Castel, Xiaoxiao Zhang, Peter N. Dodds, Russell E. Vance, Jonathan D. G. Jones, Sung Un Huh, J. Chen, Pok N. Ngou, Pingtao Ding, Jeannette L. Tenthorey, Lanxi Hu, Yan Ma, Panagiotis N. Moschou, Craig MacKenzie, Lionel Hill

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (31), pp.18832-18839. ⟨10.1073/pnas.2001185117⟩
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (31), pp.18832-18839. ⟨10.1073/pnas.2001185117⟩

Significance Animal NLRs form wheel-like structures called inflammasomes upon perception of pathogen-associated molecules. The induced proximity of the signaling domains at the center of the wheel is hypothesized to recruit caspases for the first ste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97857fcafb402adca32a74778b9f318
https://pub.epsilon.slu.se/18742/