Bioreactor-produced iPSCs-derived dopaminergic neuron-containing neural microtissues innervate and normalize rotational bias in a dose-dependent manner in a Parkinson rat model.

Autor: Prudon N; Université de Bordeaux, CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France. Electronic address: nicolas.prudon@u-bordeaux.fr., Cordero-Espinoza L; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Abarkan M; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Gurchenkov B; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Morel C; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Lepleux M; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., De Luca V; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Lartigue M; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Cabanas H; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Pujol N; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Milvoy L; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Morand P; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Moncaubeig F; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Wurtz H; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Poinçot L; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., De Marco M; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Jonckeau A; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Pletenka J; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Luquet E; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Sovera A; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Hardoüin J; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Neves IJ; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Machado-Hitau A; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Schmit K; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Piouceau L; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Guilbert S; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Manache-Alberici L; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Lanero Fidalgo M; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Dabée G; Université de Bordeaux, CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France; PIV-EXPE, Centre Broca, Université de Bordeaux, F-33000 Bordeaux, France., Dufourd T; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Schroeder J; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Alessandri K; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Bezard E; Université de Bordeaux, CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France., Faggiani E; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France., Feyeux M; TreeFrog Therapeutics, Bât A, F-33600 Pessac, France.

Publikováno v: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2024 Sep; Vol. 21 (5), pp. e00436. Date of Electronic Publication: 2024 Oct 01.