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Discovery of small molecules targeting the synergy of cardiac transcription factors GATA4 and NKX2-5
Autor:
Välimäki, M. J. (Mika J.), Tölli, M. A. (Marja A.), Kinnunen, S. M. (Sini M.), Aro, J. (Jani), Serpi, R. (Raisa), Pohjolainen, L. (Lotta), Talman, V. (Virpi), Poso, A. (Antti), Ruskoaho, H. J. (Heikki J.)
Transcription factors are pivotal regulators of gene transcription, and many diseases are associated with the deregulation of transcriptional networks. In the heart, the transcription factors GATA4 and NKX2-5 are required for cardiogenesis. GATA4 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::454f2365a0785abcb45ded8e48896c20
http://urn.fi/urn:nbn:fi-fe2019071923143
http://urn.fi/urn:nbn:fi-fe2019071923143