Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Poh-Loong Soong"'
Autor:
Filip Laco, Alan Tin-Lun Lam, Tsung-Liang Woo, Gerine Tong, Valerie Ho, Poh-Loong Soong, Elina Grishina, Kun-Han Lin, Shaul Reuveny, Steve Kah-Weng Oh
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background The production of large quantities of cardiomyocyte is essential for the needs of cellular therapies. This study describes the selection of a human-induced pluripotent cell (hiPSC) line suitable for production of cardiomyocytes in
Externí odkaz:
https://doaj.org/article/2840741df0e64bc794ee77bc6533d8be
Autor:
Mayank Dalakoti, Melvin Khee Shing Leow, Chin Meng Khoo, Hayang Yang, Lieng Hsi Ling, Mark Muthiah, Eunice Tan, Jonathan Lee, Yock Young Dan, Nicholas Chew, Wei Qiang Seow, Poh Loong Soong, Louis Gan, Rijan Gurung, Matthew Ackers-Johnson, Han Wei Hou, Karishma Sachaphibulkij, Paul MacAry, Gwen Low, Christy Ang, Tee Joo Yeo, Andie Hartanto Djohan, Tony Li, Wesley Yeung, Rodney Soh, Ching Hui Sia, Vinay Panday, Shaun S. E. Loong, Benjamin Y. Q. Tan, Leonard L. L. Yeo, Lynette Teo, Pierce Chow, Roger Foo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Through extensive multisystem phenotyping, the central aim of Project PICMAN is to correlate metabolic flexibility to measures of cardiometabolic health, including myocardial diastolic dysfunction, coronary and cerebral atherosclerosis, body
Externí odkaz:
https://doaj.org/article/3618c2fe020f4b089f6d33f4c903a6eb
Autor:
Lynn Yap, Li Yen Chong, Clarissa Tan, Swarnaseetha Adusumalli, Millie Seow, Jing Guo, Zuhua Cai, Sze Jie Loo, Eric Lim, Ru San Tan, Elina Grishina, Poh Loong Soong, Narayan Lath, Lei Ye, Enrico Petretto, Karl Tryggvason
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Ischemic heart disease, which is often associated with irreversibly damaged heart muscle, is a major global health burden. Here, we report the potential of stem cell-derived committed cardiac progenitors (CCPs) have in regenerative cardiolog
Externí odkaz:
https://doaj.org/article/efda7fe383264fd9a71daf9a83a77ec1
Autor:
Xiu-Yi Kwek, Andrew R. Hall, Wei-Wen Lim, Khairunnisa Katwadi, Poh Loong Soong, Elina Grishina, Kun-Han Lin, Gustavo Crespo-Avilan, En Ping Yap, Nur Izzah Ismail, Kroekkiat Chinda, Ying Ying Chung, Heming Wei, Winston Shim, David Montaigne, Andrew Tinker, Sang-Bing Ong, Derek J. Hausenloy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Mitochondrial dysfunction induced by acute cardiac ischemia–reperfusion (IR), may increase susceptibility to arrhythmias by perturbing energetics, oxidative stress production and calcium homeostasis. Although changes in mitochondrial morph
Externí odkaz:
https://doaj.org/article/e1c3d69e278a413bb5c1514faa5a9a65
Autor:
Irina Trautsch, Eriona Heta, Poh Loong Soong, Elif Levent, Viacheslav O. Nikolaev, Ivan Bogeski, Dörthe M. Katschinski, Manuel Mayr, Wolfram-Hubertus Zimmermann
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Redox signaling affects all aspects of cardiac function and homeostasis. With the development of genetically encoded fluorescent redox sensors, novel tools for the optogenetic investigation of redox signaling have emerged. Here, we sought to develop
Externí odkaz:
https://doaj.org/article/cddc89d2ea8c468497753b9d0edd52e5
Autor:
Asset Amenov, Nadezda Ignatyeva, Yuanyuan Dai, Poh Loong Soong, Manuela Zaccolo, Wolfgang A. Linke, Antje D. Ebert, Gerd Hasenfuss, Andreas Koschinski, Hang Xu, Malte Tiburcy, Wolfram-Hubertus Zimmermann
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
The sarcomeric troponin-tropomyosin complex is a critical mediator of excitation-contraction coupling, sarcomeric stability and force generation. We previously reported that induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) from patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0168568a7f87b14f70b7392b745cbd0
http://link.springer.com/article/10.1038/s41598-019-56597-3
http://link.springer.com/article/10.1038/s41598-019-56597-3
Autor:
Lynn Yap, Li Yen Chong, Clarissa Tan, Swarnaseetha Adusumalli, Millie Seow, Jing Guo, Zuhua Cai, Sze Jie Loo, Eric Lim, Elina Grishina, Poh Loong Soong, Narayan Lath, Lei Ye, Enrico Petretto, Karl Tryggvason
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb43bbfc396444b9f7f7b6fba93381b2
https://doi.org/10.2139/ssrn.4156707
https://doi.org/10.2139/ssrn.4156707
Autor:
Elina Grishina, Poh-Loong Soong, Kun-Han Lin, Steve Oh, Alan Tin-Lun Lam, Valerie Ho, Tsung-Liang Woo, Gerine Tong, Filip Laco, Shaul Reuveny
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background The production of large quantities of cardiomyocyte is essential for the needs of cellular therapies. This study describes the selection of a human-induced pluripotent cell (hiPSC) line suitable for production of cardiomyocytes in a fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ae4cb65aa37750abe2c1eaa4e2754d
https://doi.org/10.1186/s13287-020-01618-6
https://doi.org/10.1186/s13287-020-01618-6
Autor:
Laco, Filip, Lam, Alan Tin-Lun, Tsung-Liang Woo, Gerine Tong, Ho, Valerie, Poh-Loong Soong, Grishina, Elina, Kun-Han Lin, Reuveny, Shaul, Oh, Steve Kah-Weng
Supplementary Table S1. List of antibodies used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f9349f671f654401bd4a876f3ae7a1
Autor:
Ufuk Degirmenci, Suet Yen Chong, Karin Wuertz-Kozak, Adriano Aguzzi, Sharanya Ramanan, Jiong-Wei Wang, Shi Jie Toh, Charlene Hui Hua Fong, Rina Malathi Pannir Selvan, Marco Casarosa, Bharati Kadamb Patel, Pete J. Richards, Zi Ling Foo, Craig Wong, Yee Kit Tai, Ali Mirsaidi, Kristy Purnamawati, Stephen J. Ferguson, Jürg Fröhlich, Charmaine Ng, Alfredo Franco-Obregón, Monica Monici, Elina Grishina, Poh Loong Soong, Lei Sun, Pawel Pelczar, Chester L. Drum, Jasmine Lye Yee Yap, Jocelyn Naixin Yin, Carmine Pasquale Cerrato, Christian Beyer
Publikováno v:
The FASEB Journal, 34 (8)
Exercise modulates metabolism and the gut microbiome. Brief exposure to low mT-range pulsing electromagnetic fields (PEMFs) was previously shown to accentuate in vitro myogenesis and mitochondriogenesis by activating a calcium-mitochondrial axis upst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f82229a9754d9956a0d3ea720635c4