Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Poh San Lai"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101229- (2024)
Gene modification therapies (GMTs) are slowly but steadily making progress toward clinical application. As the majority of rare diseases have an identified genetic cause, and as rare diseases collectively affect 5% of the global population, it is inc
Externí odkaz:
https://doaj.org/article/6c1ca793661f46948184ebc64424a598
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101623- (2024)
Externí odkaz:
https://doaj.org/article/cb29ac93b7ef46878f71d7f02623156b
Autor:
Kristy Iskandar, Sunartini Hapsara, Chun Ping Liu, Rusdy Ghazali Malueka, Ery Kus Dwianingsih, Gunadi, Masafumi Matsuo, Poh San Lai
Publikováno v:
F1000Research, Vol 11 (2023)
Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are allelic disorders caused by mutations in the DMD gene. The full mutation spectrum of the DMD gene in Indonesian patients is currently unknown. Mutation-specific ther
Externí odkaz:
https://doaj.org/article/5d778e3de77b4449ab4539002cc11676
Autor:
Kristy Iskandar, Sunartini, Farida Niken Astari, Rizki Amalia Gumilang, Nissya Ilma, Ni Putu Shartyanie, Guritno Adistyawan, Grace Tan, Gunadi, Poh San Lai
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Emery-Dreifuss Muscular Dystrophy (EDMD) is an uncommon genetic disease among the group of muscular dystrophies. EDMD is clinically heterogeneous and resembles other muscular dystrophies. Mutation of the lamin A/C (LMNA) gene, whi
Externí odkaz:
https://doaj.org/article/1d628b10e49e4ee6a5c5cd1f3a4793df
Autor:
Ka Zhang, Shaun S. E. Loong, Linus Z. H. Yuen, Narayanaswamy Venketasubramanian, Hui-Lin Chin, Poh San Lai, Benjamin Y. Q. Tan
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 12, p 495 (2023)
Ischemic stroke is a heterogeneous condition influenced by a combination of genetic and environmental factors. Recent advancements have explored genetics in relation to various aspects of ischemic stroke, including the alteration of individual stroke
Externí odkaz:
https://doaj.org/article/38edc48b0caa44cca43b3cd587fd6fe3
Autor:
Anne Chong, Serenella Tolomeo, Yue Xiong, Dario Angeles, Mike Cheung, Benjamin Becker, Poh San Lai, Zhen Lei, Fabio Malavasi, Qianzi Tang, Soo Hong Chew, Richard P. Ebstein
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Converging evidence suggests that oxytocin (OT) is associated with creative thinking (CT) and that release of OT depends on ADP ribosyl-cyclases (CD38 and CD157). Neural mechanisms of CT and OT show a strong association with dopaminergic (DA
Externí odkaz:
https://doaj.org/article/918e8fe0a3354e3f8787043805e3d29f
Publikováno v:
Human Genomics, Vol 16, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/d42cc90ab501427e8afca7221af60f69
Autor:
Vicki Xafis, G Owen Schaefer, Markus K Labude, Yujia Zhu, Soren Holm, Roger Sik-Yin Foo, Poh San Lai, Ruth Chadwick
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009741 (2021)
Much has been written about gene modifying technologies (GMTs), with a particularly strong focus on human germline genome editing (HGGE) sparked by its unprecedented clinical research application in 2018, shocking the scientific community. This paper
Externí odkaz:
https://doaj.org/article/689ad2eb3b564d6eb6551d5e7b25fb64
Autor:
Kristy Iskandar, Ery Kus Dwianingsih, Linda Pratiwi, Alvin Santoso Kalim, Hasna Mardhiah, Alifiani H. Putranti, Dian K. Nurputra, Agung Triono, Elisabeth S. Herini, Rusdy G. Malueka, Gunadi, Poh San Lai, Sunartini
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
Abstract Objective Duchenne/Becker muscular dystrophy (DMD/BMD) is the most common genetic neuromuscular disease in children, resulting from a defect in the DMD gene located on Xp21.2. The new emerging treatment using exon skipping strategy is tailor
Externí odkaz:
https://doaj.org/article/546746b927424d95a2737bb426870e83
Publikováno v:
BMC Psychology, Vol 7, Iss 1, Pp 1-10 (2019)
Abstract Background Whereas meditation training has been purported to support slower cellular aging, little work has explored the association among different facets of dispositional mindfulness, self-compassion, and cellular aging. The present study
Externí odkaz:
https://doaj.org/article/8f975adb242e4e7cba2828f99bed9aa1