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Expression, Purification and Refolding of a Human Na V 1.7 Voltage Sensing Domain with Native-like Toxin Binding Properties.

Autor: Schroder RV; Department of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA.; The Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, 365 Fifth Avenue, New York, NY 10016, USA., Cohen LS; Department of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA., Wang P; Department of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA., Arizala JD; Department of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA.; The Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, 365 Fifth Avenue, New York, NY 10016, USA., Poget SF; Department of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA.; The Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, 365 Fifth Avenue, New York, NY 10016, USA.; The Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, 365 Fifth Avenue, New York, NY 10016, USA.

Publikováno v: Toxins [Toxins (Basel)] 2021 Oct 12; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 12.

Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models.

Autor: Leffler AE; Neuroscience Graduate Program, Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY 10016., Kuryatov A; Department of Neuroscience, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104., Zebroski HA; Proteomics Resource Center, The Rockefeller University, New York, NY 10065., Powell SR; Proteomics Resource Center, The Rockefeller University, New York, NY 10065., Filipenko P; Department of Chemistry, Belfer Research Center-Hunter College, New York, NY 10021.; Division of Invertebrate Zoology, The American Museum of Natural History, New York, NY 10024.; Department of Biochemistry, Weill Cornell Medical College, Cornell University, New York, NY 10021., Hussein AK; Department of Chemistry, College of Staten Island, Staten Island, NY 10314.; Program in Biochemistry, The Graduate Center, City University of New York, New York, NY 10016., Gorson J; Department of Chemistry, Belfer Research Center-Hunter College, New York, NY 10021.; Division of Invertebrate Zoology, The American Museum of Natural History, New York, NY 10024.; Department of Biochemistry, Weill Cornell Medical College, Cornell University, New York, NY 10021.; Program in Biochemistry, The Graduate Center, City University of New York, New York, NY 10016., Heizmann A; Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80336 Munich, Germany., Lyskov S; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218., Tsien RW; NYU Neuroscience Institute and the Department of Neuroscience and Physiology, New York University School of Medicine, New York, NY 10016; richard.tsien@nyumc.org mholford@hunter.cuny.edu., Poget SF; Department of Chemistry, College of Staten Island, Staten Island, NY 10314.; Program in Biochemistry, The Graduate Center, City University of New York, New York, NY 10016., Nicke A; Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80336 Munich, Germany., Lindstrom J; Department of Neuroscience, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104., Rudy B; NYU Neuroscience Institute and the Department of Neuroscience and Physiology, New York University School of Medicine, New York, NY 10016., Bonneau R; Department of Biology, New York University, New York, NY 10003.; Courant Institute of Mathematical Sciences, New York University, New York, NY 10012.; Center for Computational Biology, Simons Foundation, New York, NY 10010., Holford M; Department of Chemistry, Belfer Research Center-Hunter College, New York, NY 10021; richard.tsien@nyumc.org mholford@hunter.cuny.edu.; Division of Invertebrate Zoology, The American Museum of Natural History, New York, NY 10024.; Department of Biochemistry, Weill Cornell Medical College, Cornell University, New York, NY 10021.; Program in Biochemistry, The Graduate Center, City University of New York, New York, NY 10016.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Sep 19; Vol. 114 (38), pp. E8100-E8109. Date of Electronic Publication: 2017 Sep 05.

Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA.

Autor: Rivera-Torres IO; LaGuardia Community College, City University of New York, Long Island City, NY 11101, USA., Jin TB; Department of Chemistry, CUNY Graduate Center and Institute for Macromolecular Assemblies, College of Staten Island, City University of New York, Staten Island, NY 10314, USA., Cadene M; The Rockefeller University, New York, NY 10065, USA., Chait BT; The Rockefeller University, New York, NY 10065, USA., Poget SF; Department of Chemistry, CUNY Graduate Center and Institute for Macromolecular Assemblies, College of Staten Island, City University of New York, Staten Island, NY 10314, USA.

Publikováno v: Scientific reports [Sci Rep] 2016 Apr 05; Vol. 6, pp. 23904. Date of Electronic Publication: 2016 Apr 05.