Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Podtcheko, A."'
Autor:
Podtcheko, A., Ohtsuru, A., Namba, H., Saenko, V., Starenki, D., Palona, I., Sedliarou, I., Rogounovitch, T., Yamashita, S.
Publikováno v:
Radiation Research, 2006 Jan 01. 165(1), 35-42.
Externí odkaz:
https://www.jstor.org/stable/3581495
Autor:
Norisato Mitsutake, Shunichi Yamashita, Akira Ohtsuru, Dmytro Starenki, Kazuo Umezawa, Yuji Nagayama, Alexei Podtcheko, Vladimir Saenko, Hiroyuki Namba, Iryna Palona, Ilya Sedliarou
Publikováno v:
Endocrinology. 147:5699-5707
The BRAFV600E mutation is closely linked to tumorigenesis and malignant phenotype of papillary thyroid cancer. Signaling pathways activated by BRAFV600E are still unclear except a common activation pathway, MAPK cascade. To investigate the possible t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348f868fdc4bf48e38f1a56c021334a8
https://doi.org/10.1210/en.2006-0400
https://doi.org/10.1210/en.2006-0400
Autor:
Akira Ohtsuru, Tatiana Rogounovitch, Ilya Sedliarou, Vladimir Saenko, Alexei Podtcheko, Shunichi Yamashita, Dmytro Starenki, Hiroyuki Namba, Iryna Palona
Publikováno v:
Radiation Research. 165:35-42
Gleevec, a selective tyrosine kinase inhibitor, retarded the growth of anaplastic thyroid cancer cell lines in vitro and in vivo through selective inhibition of ABL tyrosine kinase activity. In the present study, we investigated the ability of Gleeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21b817368f681400be22755707736a4
https://doi.org/10.1667/rr3466.1
https://doi.org/10.1667/rr3466.1
Autor:
Alexei Podtcheko, Vladimir Saenko, Junichi KurebayashiI, Akira Ohtsuru, Shunichi Yamashita, Satoshi Tsuda
Publikováno v:
International Congress Series. 1258:157-161
A non-receptor-type tyrosine kinase, c-Abl, interacts with the tumor suppressor protein p53 and is critical in the regulation of the cell cycle. To establish a molecular targeting therapy for anaplastic thyroid carcinomas with mutated p53, we studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f3f38e816e0341587bf83cb492e8cd4
https://doi.org/10.1016/s0531-5131(03)01150-6
https://doi.org/10.1016/s0531-5131(03)01150-6
Autor:
Akira Ohtsuru, Satoshi Tsuda, Vladimir Saenko, Shunichi Yamashita, Hiroaki Tamura, Mariko Morishita, Alexei Podtcheko, Hiroyuki Namba, Miyoko Iwamatsu
Publikováno v:
International Congress Series. 1258:273-276
The anaplastic thyroid carcinoma has a poor therapeutic response and leads to high mortality. The nonreceptor tyrosine kinase, c-ABL, along with one of the p53 downstream targets, is critical in the regulation of the cell cycle and radiation-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c8a3e1bc1706dbf5382791a545ffc0a
https://doi.org/10.1016/s0531-5131(03)01205-6
https://doi.org/10.1016/s0531-5131(03)01205-6
Autor:
Alexei Podtcheko, Akira Ohtsuru, Tatiana Rogounovitch, Hiroyuki Namba, Norisato Mitsutake, Shu Takakura, Dmitry Bulgin, Iryna Palona, Vladimir Saenko, Shunichi Yamashita
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 16(3)
The high radioresistance of anaplastic thyroid cancer (ATC) and cultured ATC cells stipulates for the means of increasing their radiosensitivity. It has been shown that c-Jun NH(2)-terminal kinase (JNK) activation is one of the manifestations of radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6da8fc9fff5c6fe1525cfd46c4f2363
https://pubmed.ncbi.nlm.nih.gov/16571083
https://pubmed.ncbi.nlm.nih.gov/16571083
Autor:
Serik Meirmanov, Akira Ohtsuru, Tatiana Rogounovitch, Iryna Polona, Alexei Podtcheko, Shunichi Yamashita, Dmitriy V. Starenki, Hiroyuki Namba, Vladimir Saenko
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 15(4)
Premature senescence may play an important role as an acute, drug-, or ionizing radiation (IR)-inducible growth arrest program along with interphase apoptosis and mitotic catastrophe. The aim of the study was to evaluate whether IR can induce senesce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a68e4c59e3808f40ec83bbfcbacb980
https://pubmed.ncbi.nlm.nih.gov/15876151
https://pubmed.ncbi.nlm.nih.gov/15876151
Autor:
Podtcheko, Alexei
長崎大学学位論文 学位記番号:博(医)甲第1,189号 学位授与年月日:平成17年3月18日
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::37aadbcf0ee99a8690a57cd4b819274f
http://hdl.handle.net/10069/7075
http://hdl.handle.net/10069/7075
Autor:
Alexei Podtcheko, Hirouki Namba, Shigeru Kanda, Vladimir Saenko, Masahiro Nakashima, Satoshi Tsuda, Akira Ohtsuru, Shunichi Yamashita, Junichi Kurebayashi, Norisato Mitsutake
Publikováno v:
The Journal of clinical endocrinology and metabolism. 88(4)
To establish a molecular targeting therapy for anaplastic thyroid carcinomas, we studied the effect of the specific tyrosine kinase inhibitor, STI571, on anaplastic thyroid cancer cell lines highly expressing c-ABL ARO (mutated p53) and FRO (undetect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4957d0130dcc9bf1bb379153df2707f1
https://pubmed.ncbi.nlm.nih.gov/14557495
https://pubmed.ncbi.nlm.nih.gov/14557495
Autor:
Bulgin, Dmitry, Podtcheko, Alexei, Takakura, Shu, Mitsutake, Norisato, Namba, Hiroyuki, Saenko, Vladimir, Ohtsuru, Akira, Rogounovitch, Tatiana, Palona, Iryna, Yamashita, Shunichi
Publikováno v:
Thyroid; Mar2006, Vol. 16 Issue 3, p217-224, 8p