Zobrazeno 1 - 10
of 3 546
pro vyhledávání: '"Podoplanin"'
Autor:
Rachel E. Nicoletto, Cayla J. Holdcraft, Ariel C. Yin, Edward P. Retzbach, Stephanie A. Sheehan, Amanda A. Greenspan, Christopher M. Laugier, Jason Trama, Caifeng Zhao, Haiyan Zheng, Gary S. Goldberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Nontransformed cells form heterotypic cadherin junctions with adjacent transformed cells to inhibit tumor cell growth and motility. Transformed cells must override this form of growth control, called “contact normalization”, to invade an
Externí odkaz:
https://doaj.org/article/57de1dc4fa8647f899e49bfc48148f7e
Publikováno v:
Journal of Dentistry, Vol 25, Iss 2, Pp 118-124 (2024)
Statment of the Problem: Podoplanin can indicate the lymphangiogenesis. On the other hand, lymphangiogenesis affects the biological behavior of lesions. The clinical behavior of odontogenic keratocysts (OKC) and dentigerous cysts (DC) is different.Pu
Externí odkaz:
https://doaj.org/article/36e1f626f1b74fbfa7d066e115012931
Autor:
Ha Yeong Kim, Han Su Kim
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Mesenchymal stem cells (MSCs) are widely used in the development of therapeutic tools in regenerative medicine. However, their quality decreases during in vitro expansion because of heterogeneity and acquired cellular senescence.
Externí odkaz:
https://doaj.org/article/6ddc36b40ac2482bb4a714e5f71a4b32
Autor:
Aud-Malin Karlsson Hovd, Saba Nayar, Charlotte G. Smith, Premasany Kanapathippillai, Valentina Iannizzotto, Francesca Barone, Kristin Andreassen Fenton, Hege Lynum Pedersen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Tertiary lymphoid structures (TLSs) are formed in tissues targeted by chronic inflammation processes, such as infection and autoimmunity. In Sjögren’s disease, the organization of immune cells into TLS is an important part of disease progression.
Externí odkaz:
https://doaj.org/article/fc34f1ed464e4a7b92d4db6f82667450
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Podoplanin (PDPN) expressed on tumour cells interacts with platelet C-type lectin-like receptor 2 (CLEC-2). This study aimed to investigate the role of the PDPN-platelet CLEC-2 interaction in melanoma pulmonary metastasis. Methods
Externí odkaz:
https://doaj.org/article/b1123be300d24e8eac31f26c52db8a07
Autor:
ZHANG Yuyang, WANG Hongjiang
Publikováno v:
Zhongguo linchuang yanjiu, Vol 37, Iss 3, Pp 329-333 (2024)
Breast cancer has become the most common malignant tumor in women, and its diagnosis and treatment principles mainly depend on the traditional histological and molecular pathological features. However, the systemic metastasis of breast cancer begins
Externí odkaz:
https://doaj.org/article/4114e46e20a94428a214453aa775f20f
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract C-type lectin-like receptor-2 (CLEC-2) is a member of the C-type lectin superfamily of cell surface receptors. The first confirmed endogenous and exogenous ligands of CLEC-2 are podoplanin and rhodocytin, respectively. CLEC-2 is expressed on
Externí odkaz:
https://doaj.org/article/d3f2055582274a479e406a16cf2de3ac
Autor:
Yangkang Zheng, Pengyu Wang, Li Zhao, Lianping Xing, Hao Xu, Ning Li, Yongjian Zhao, Qi Shi, Qianqian Liang, YongJun Wang
Publikováno v:
Journal of Orthopaedic Translation, Vol 45, Iss , Pp 66-74 (2024)
Background: The musculoskeletal system contains an extensive network of lymphatic vessels. Decreased lymph flow of the draining collecting lymphatics usually occurs in clinic after traumatic fractures. However, whether defects in lymphatic drainage c
Externí odkaz:
https://doaj.org/article/a82fe6e0951a4cabb92bb4d199c97252
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Autor:
Sunao Ito, Akira Koshino, Chengbo Wang, Takahiro Otani, Masayuki Komura, Akane Ueki, Shunsuke Kato, Hiroki Takahashi, Masahide Ebi, Naotaka Ogasawara, Toyonori Tsuzuki, Kenji Kasai, Kunio Kasugai, Shuji Takiguchi, Satoru Takahashi, Shingo Inaguma
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 4, Pp n/a-n/a (2024)
Abstract Evidence for the tumour‐supporting capacities of the tumour stroma has accumulated rapidly in colorectal cancer (CRC). Tumour stroma is composed of heterogeneous cells and components including cancer‐associated fibroblasts (CAFs), small
Externí odkaz:
https://doaj.org/article/b48315930f8a45719e774d53e6793041