Výsledky vyhledávání - "Poda Suresh Babu"

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Development of an Aequorin Luminescence Calcium Assay for High-Throughput Screening Using a Plate Reader, the LumiLux

Autor: Poda Suresh Babu, Michelle A. Uberti, Arun Ranganathn, Michael Sabio, Claus T. Christoffersen, Veena Menon, Vincent H. Jorgensen, Kenneth A. Jones

Publikováno v: ASSAY and Drug Development Technologies. 6:787-794

A luminescence assay using a new plate reader, the LumiLux (PerkinElmer, Waltham, MA), has been validated for high-throughput screening (HTS). In this study, we compared the aequorin luminescence-based calcium mobilization assay to the fluorescence-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2671105a552d9b37d214aa7192ea90
https://doi.org/10.1089/adt.2008.157

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Akademický článek

The identification of GPR3 inverse agonist AF64394; The first small molecule inhibitor of GPR3 receptor function

Autor: Jensen, Thomas, Elster, Lisbeth, Nielsen, Søren Møller, Poda, Suresh Babu, Loechel, Frosty, Volbracht, Christiane, Klewe, Ib Vestergaard, David, Laurent, Watson, Stephen P.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 15 November 2014 24(22):5195-5198

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Akademický článek

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A truncated form of CKβ8-1 is a potent agonist for human formyl peptide-receptor-like 1 receptor

Autor: Marie-Odile Roy, Poda Suresh Babu, Patricia Laplante, Lembo Paola, Eric Grazzini, Sultan Ahmad, Duncan Henderson, Lorna Bowers, Caroline Grahames, Aram Elagoz, Sylvia Salter

Publikováno v: British Journal of Pharmacology. 141:37-46

1. Human formyl peptide-receptor-like-1 (FPRL-1) is a promiscuous G protein-coupled receptor (GPCR), and belongs to a chemoattractant receptor family protein. This receptor has been reported to interact with various host-derived peptides and lipids i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ea558f80bb8b2123018e02996ec66d8
https://doi.org/10.1038/sj.bjp.0705592

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Interaction Between Dax-1 and Steroidogenic Factor-1 in Vivo: Increased Adrenal Responsiveness to ACTH in the Absence of Dax-1

Autor: J. Larry Jameson, Baxter Jeffs, Sonalee P. Shah, David L. Bavers, Felix Beuschlein, Gary D. Hammer, Poda Suresh Babu

Publikováno v: Endocrinology. 143:665-673

Two nuclear receptors, dosage-sensitive sex reversal adrenal hypoplasia congenita, critical region on the X chromosome gene-1 (Dax-1) and steroidogenic factor-1 (SF-1), are required for adrenal development and function. In vitro assays suggest that D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a30a2b9655a6aecf3ab7e6ee6d68919
https://doi.org/10.1210/endo.143.2.8658

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Delay in Sexual Maturity of the Follicle-Stimulating Hormone Receptor Knockout Male Mouse1

Autor: Poda Suresh Babu, Carlos R. Morales, M. Ram Sairam, Hanumanthappa Krishnamurthy

Publikováno v: Biology of Reproduction. 65:522-531

In the highly organized and complex process of mammalian spermatogenesis, the development of an undifferentiated diploid germ cell into a fully differentiated and mature spermatozoon is orchestrated in a time frame unique for each species including m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abac22b7a2c70917fad9f81a998999b9
https://doi.org/10.1095/biolreprod65.2.522

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Activation of Extracellular-regulated Kinase Pathways in Ovarian Granulosa Cells by the Novel Growth Factor Type 1 Follicle-stimulating Hormone Receptor

Autor: M. Ram Sairam, P. Jorge Chedrese, Poda Suresh Babu, Hanumanthappa Krishnamurthy

Publikováno v: Journal of Biological Chemistry. 275:27615-27626

Follicle-stimulating hormone (FSH) regulated growth and function of the ovarian follicle was previously thought to be mediated solely through activation of Gs-coupled receptors. In this study, we show for the first time that this function is predomin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d50de40f1c3e02fecb328b8d16764685
https://doi.org/10.1074/jbc.m003206200

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Role of phosphorylation, gene dosage and Dax-1 in SF-1 mediated steroidogenesis

Autor: David L. Bavers, Gary D. Hammer, Poda Suresh Babu, Sonalee P. Shah

Publikováno v: Endocrine research. 26(4)

The mechanisms by which SF-1 (Steroidogenic Factor-1) and Dax-1 (Dosage-sensitive sex reversal-Adrenal hypoplasia congenita critical region on the X chromosome) dictate adrenal-specific transcriptional programs are the focus of this laboratory. SF-1-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee3bdc5ed67960e38a15c40a59ca060
https://pubmed.ncbi.nlm.nih.gov/11196480

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Renal lesions in streptozotocin-induced diabetic rats maintained on onion and capsaicin containing diets

Autor: Krishnapura Srinivasan, Poda Suresh Babu

Publikováno v: The Journal of nutritional biochemistry. 10(8)

Onion (Allium cepa) powder and capsaicin, the pungent principle of red pepper (Capsicum annum) were added in the amounts of 3 g% and 15 mg%, respectively, to the diet of streptozotocin-induced diabetic Wistar rats for 8 weeks. The presence of renal l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a930341efbda9b37b732ea6e04fb40ef
https://pubmed.ncbi.nlm.nih.gov/15539326

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