Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Po-Ying Chan"'
Autor:
Shu-I Wu, Chien-Chen Wu, Pei-Joung Tsai, Li-Hao Cheng, Chih-Chieh Hsu, Ian-Kai Shan, Po-Ying Chan, Ting-Wei Lin, Chih-Jung Ko, Wan-Lin Chen, Ying-Chieh Tsai
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Background: Information technology (IT) is an industry related to the production of computers, information processing, and telecommunications. Such industries heavily rely on the knowledge and solutions provided by IT specialists. Previous reports fo
Externí odkaz:
https://doaj.org/article/1529f61b92c04831b05ac6994cd6ec04
Autor:
Devin Sok, Uri Laserson, Jonathan Laserson, Yi Liu, Francois Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen F. Saye, Khoa Le, Alison Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M. Walker, Birgitte B. Simen, Elizabeth P. St. John, Po-Ying Chan-Hui, Kristine Swiderek, Stephen H. Kleinstein, Galit Alter, Michael S. Seaman, Arup K. Chakraborty, Daphne Koller, Ian A. Wilson, George M. Church, Dennis R. Burton, Pascal Poignard
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12 (2013)
Externí odkaz:
https://doaj.org/article/3d37c901f805490294c80ad1ef2a5381
Autor:
Devin Sok, Uri Laserson, Jonathan Laserson, Yi Liu, Francois Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen F Saye, Khoa Le, Alison Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M Walker, Birgitte B Simen, Elizabeth P St John, Po-Ying Chan-Hui, Kristine Swiderek, Steven H Kleinstein, Galit Alter, Michael S Seaman, Arup K Chakraborty, Daphne Koller, Ian A Wilson, George M Church, Dennis R Burton, Pascal Poignard
Publikováno v:
PLoS Pathogens, Vol 9, Iss 11, p e1003754 (2013)
Broadly neutralizing HIV antibodies (bnAbs) are typically highly somatically mutated, raising doubts as to whether they can be elicited by vaccination. We used 454 sequencing and designed a novel phylogenetic method to model lineage evolution of the
Externí odkaz:
https://doaj.org/article/2904622cd3c446a68927030a0ec4fe05
Autor:
Kristine M. Swiderek, Christy Boozer, Alison Fitch, Aurelio Bonavia, Brad Greenfield, Mark Branum, Po-Ying Chan-Hui, Paul A. Algate, Claire Sutherland
Publikováno v:
Cancer Research. 75:P2-16
Unlike HER2-positive breast cancer, there are limited treatment options for patients diagnosed with triple negative and endocrine resistant HER2-negative breast cancer, and as such HER2-negative breast cancer represents a significant unmet medical ne
Autor:
Ellen S. Vitetta, Dean H. Hamer, James E. Robinson, Seth H. Pincus, Victor Ghetie, Weizao Chen, Grace A. Maresh, Mei-Yun Zhang, Po-Ying Chan-Hui, Dimiter S. Dimitrov, Kejing Song
Publikováno v:
Journal of Virology. 91
The envelope (Env) glycoprotein of HIV is the only intact viral protein expressed on the surface of both virions and infected cells. Env is the target of neutralizing antibodies (Abs) and has been the subject of intense study in efforts to produce HI
Autor:
Witold Cieplak, Brian Long, Terri Wrin, Barbara Sloan, Jose M. Rivera, Sofiya A. Galkina, Ukina R. Sanford, Mary E. Moreno, Po-Ying Chan-Hui, Pheroze Joshi, Ekaterina Maidji, Cheryl A. Stoddart, Galina Kosikova
Publikováno v:
Virology, vol 462-463, iss 1
Highly potent broadly neutralizing human monoclonal antibodies hold promise for HIV prophylaxis and treatment. We used the SCID-hu Thy/Liv and BLT humanized mouse models to study the efficacy of these antibodies, primarily PG16, against HIV-1 clades
Autor:
Yan Liu, Ten Feizi, Dennis R. Burton, Alejandro Ramirez, Benjamin von Bredow, Kristine M. Swiderek, Alejandra Ramos, Chung-Yi Wu, Marit J. van Gils, Jeong Hyun Lee, Khoa Le, Chi-Hui Liang, Ian A. Wilson, Michael B. Zwick, Rogier W. Sanders, Chi-Huey Wong, Andrew B. Ward, Claudia Blattner, Po-Ying Chan-Hui, Ronald Derking, Wayne C. Koff, Pascal Poignard, Katie J. Doores, Michael S. Seaman, David T. Evans, James C. Paulson, Sachin S. Shivatare, Emilia Falkowska, Ryan McBride, John P. Moore
Publikováno v:
Immunity, 40(5), 657-668. Cell Press
SummaryBroadly neutralizing HIV antibodies are much sought after (a) to guide vaccine design, both as templates and as indicators of the authenticity of vaccine candidates, (b) to assist in structural studies, and (c) to serve as potential therapeuti
Autor:
Phillip W. Hammond, Laura M. Walker, Sheng-Kai Wang, Pham Phung, Protocol G. Principal Investigators, Michael Huber, Jennifer L. Mitcham, Chi-Huey Wong, Terri Wrin, Robert Pejchal, Dennis R. Burton, Jean-Philippe Julien, Po-Ying Chan-Hui, Ole A. Olsen, Emilia Falkowska, Melissa Simek, Wayne C. Koff, Ian A. Wilson, Sanjay Phogat, Pascal Poignard, Katie J. Doores, Alejandra Ramos, Steven P. Fling, Matthew Moyle
Publikováno v:
Nature. 477:466-470
Broadly neutralizing antibodies against highly variable viral pathogens are much sought after to treat or protect against global circulating viruses. Here we probed the neutralizing antibody repertoires of four human immunodeficiency virus (HIV)-infe
Autor:
Yoshihiro Kawaoka, Masato Hatta, Andres G. Grandea, Jennifer L. Mitcham, Philip Hammond, Witold Cieplak, Maki Kiso, Ole A. Olsen, Mark A. Renshaw, Matthew Moyle, Kyoko Shinya, Shaun M. Stewart, Thomas C. Cox, Andrew Pekosz, Po-Ying Chan-Hui, Michael L. Grantham
Publikováno v:
Proceedings of the National Academy of Sciences. 107:12658-12663
Influenza remains a serious public health threat throughout the world. Vaccines and antivirals are available that can provide protection from infection. However, new viral strains emerge continuously because of the plasticity of the influenza genome,
Autor:
Dennis R. Burton, Laura M. Walker, Steven P. Fling, Jennifer Lehrman, Denise Wagner, Timothy J. Zamb, Julie L. Goss, Phillip W. Hammond, Pham Phung, Pascal Poignard, Sanjay Phogat, Jennifer L. Mitcham, Ole A. Olsen, Wayne C. Koff, Steven Frey, Po-Ying Chan-Hui, Frances Priddy, Terri Wrin, Protocol G. Principal Investigators, Melissa Simek, Stephen M. Kaminsky, Matthew Moyle
Publikováno v:
Science. 326:285-289
Anti-HIV Antibodies One of the top priorities for an HIV vaccine is the ability to elicit a broadly neutralizing antibody response, which should provide the best protection against infection. In the 25 years since the discovery of HIV, very few broad