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Akademický článek

Metformin Protects Against Carbon Tetrachloride Hepatotoxicity in Mice

Autor: Michel K.T. Poon, Po-Yee Chiu, Duncan H.F. Mak, Kam-Ming Ko

Publikováno v: Journal of Pharmacological Sciences, Vol 93, Iss 4, Pp 501-504 (2003)

ABSTRACT: In the present study, the hepatoprotective effect of metformin (Met), a dimethylbiguanide anti-hyperglycemic, was examined in a mouse model of liver damage induced by chronic repeated administration of carbon tetrachloride (CCl4) (5 μl/kg,

Externí odkaz: https://doaj.org/article/0caab33260ae411a887b06e8ad73aa44

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Akademický článek

Cytochrome P-450-catalyzed reactive oxygen species production mediates the (-)schisandrin B-induced glutathione and heat shock responses in H9c2 cardiomyocytes.

Autor: Na Chen¹, Po Yee Chiu¹, Hoi Yan Leung¹, Kam Ming Ko¹ bcrko@ust.hk

Publikováno v: Indian Journal of Pharmacology. Apr2012, Vol. 44 Issue 2, p204-209. 6p. 1 Diagram, 4 Graphs.

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Akademický článek

Myocardial post-conditioning with Danshen- Gegen decoction protects against isoproterenol-induced myocardial injury via a PKCϵ/mKATPmediated pathway in rats.

Autor: Sze Man Wong¹, Po Yee Chiu¹, Hoi Yan Leung¹, Limin Zhou², Zhong Zuo², Lam, Philip Y.¹, Kam Ming Ko¹ bcrko@ust.hk

Publikováno v: Chinese Medicine. 2011, Vol. 6 Issue 1, p1-10. 10p.

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Akademický článek

Schisandrin B-induced increase in cellular glutathione level and protection against oxidant injury are mediated by the enhancement of glutathione synthesis and regeneration in AML12 and H9c2 cells.

Autor: Po Yee Chiu¹, Kam Ming Ko¹ bcrko@ust.hk

Publikováno v: Biofactors. 2006, Vol. 26 Issue 4, p221-230. 10p. 1 Diagram, 1 Chart, 4 Graphs.

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Akademický článek

Time-dependent enhancement in mitochondrial glutathione status and ATP generation capacity by schisandrin B treatment decreases the susceptibility of rat hearts to ischemia-reperfusion injury.

Autor: Po Yee Chiu¹, Kam Ming Ko¹ bcrko@ust.hk

Publikováno v: Biofactors. 2003, Vol. 19 Issue 1/2, p43-51. 9p. 1 Diagram, 4 Graphs.

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Akademický článek

Hepatoprotective action of schisandrin B against carbon tetrachloride toxicity was mediated by both enhancement of mitochondrial glutathione status and induction of heat shock proteins in mice.

Autor: Man Ho Tang¹, Po Yee Chiu¹, Kam Ming Ko¹ bcrko@ust.hk

Publikováno v: Biofactors. 2003, Vol. 19 Issue 1/2, p33-42. 10p. 1 Diagram, 1 Chart, 3 Graphs.

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Neuroprotection Against Oxidative Injury by a Nucleic Acid–Based Health Product (Squina DNA) Through Enhancing Mitochondrial Antioxidant Status and Functional Capacity

Autor: Phillip Y Lam, Na Chen, Kam Ming Ko, Hoi Yan Leung, Po Yee Chiu

Publikováno v: Journal of Medicinal Food. 15:629-638

High levels of reactive oxygen species inflict oxidative damage on various cellular components that eventually culminate in a variety of diseases. This study investigated the cytoprotective effects of a nucleic acid-based health product (Squina [Hong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78176dca60543a561cb9291bb1016d5
https://doi.org/10.1089/jmf.2011.2041

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Prooxidant-Induced Glutathione Antioxidant Response in Vitro and in Vivo: A Comparative Study between Schisandrin B and Curcumin

Autor: Kam Ming Ko, Po Yee Chiu, Pou Kuan Leong

Publikováno v: Biological and Pharmaceutical Bulletin. 35:464-472

We investigated whether two naturally-occurring prooxidants, namely, schisandrin B (Sch B) and curcumin, and a synthetic prooxidant, menadione, can invariably elicit cyto/hepatoprotective responses against oxidant-induced injury. Results showed that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d109af7081f14053070ad1bbfcfd61d
https://doi.org/10.1248/bpb.35.464

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Schisandrin B protects against solar irradiation-induced oxidative injury in BJ human fibroblasts

Autor: Po Yee Chiu, Chung Wai Yan, Kam Ming Ko, Philip Y. Lam

Publikováno v: Fitoterapia. 82:682-691

The effects of schisandrin B (Sch B) and its analogs on solar irradiation-induced oxidative injury were examined in BJ human fibroblasts. Sch B and schisandrin C (Sch C) increased cellular reduced glutathione (GSH) level and protected against solar i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c2f1eae01b3fd3acf86e34c0dff5c8
https://doi.org/10.1016/j.fitote.2011.02.010

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Schisandrin B protects against solar irradiation-induced oxidative stress in rat skin tissue

Autor: Po Yee Chiu, Kam Ming Ko, Hoi Yan Leung, Philip Y. Lam, Chung Wai Yan

Publikováno v: Fitoterapia. 82:393-400

Schisandrin B (Sch B) and schisandrin C (Sch C), but not schisandrin A and dimethyl diphenyl bicarboxylate, protected rat skin tissue against solar irradiation-induced oxidative injury, as evidenced by a reversal of solar irradiation-induced changes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dd7d4fa562f4f2986da7596ed48f6e
https://doi.org/10.1016/j.fitote.2010.11.018

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