Zobrazeno 1 - 10
of 347
pro vyhledávání: '"Po-Lin Kuo"'
Autor:
Ya-Ling Hsu, Meng-Chi Yen, Wei-An Chang, Pei-Hsun Tsai, Yi-Chung Pan, Ssu-Hui Liao, Po-Lin Kuo
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract Background Metastasis is the major cause of death from breast cancer. Colonization and adaption of metastatic cells in distant organs is a rate-limiting step of the cancer spreading. The underlying mechanisms responsible for the colonization
Externí odkaz:
https://doaj.org/article/48215931bbcc4d4d8e0c3638dad99ac7
Autor:
Hsiang-Ying Lee, Ching-Chia Li, Wei-Ming Li, Ya-Ling Hsu, Hsin-Chih Yeh, Hung-Lung Ke, Bi Wen Yeh, Chun-Nung Huang, Chien-Feng Li, Po-Lin Kuo, Wen-Jeng Wu
Publikováno v:
PeerJ, Vol 9, p e11343 (2021)
Background We aimed to identify prognostic biomarkers of upper tract urothelial carcinomas (UTUCs), including microRNAs (miRNAs) and genes which account for only 5% to 10% of all urothelial carcinomas (UCs). In Taiwan, this figure is markedly higher,
Externí odkaz:
https://doaj.org/article/5be971bd39a142eb96eb6b04f7a0472f
Autor:
Yi-Chun Tsai, Po-Lin Kuo, Wei-Wen Hung, Ling-Yu Wu, Ping-Hsun Wu, Wei-An Chang, Mei-Chuan Kuo, Ya-Ling Hsu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 543-555 (2018)
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Mesangial cell (MC) loss is correlated with worsening renal function in DN. Disturbance of angiopoietin (Angpt)/Tie ligand-receptor system causes inflammation and abnormal ang
Externí odkaz:
https://doaj.org/article/b64eb79bdd3f4110935c44cce0958f12
Autor:
Wei-An Chang, Chia-Min Chen, Chau-Chyun Sheu, Ssu-Hui Liao, Ya-Ling Hsu, Ming-Ju Tsai, Po-Lin Kuo
Publikováno v:
Molecules, Vol 25, Iss 22, p 5458 (2020)
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease. Currently, therapeutic options are limited for this fatal disease. Curcumin, with its pleiotropic effects, has been studied for its potential therapeutic util
Externí odkaz:
https://doaj.org/article/0c47ec66a38c4c1b814a197d08d1bfe7
Autor:
I-Jeng Yeh, Kuan-Ting Liu, Jheng-Heng Shen, Yen-Hung Wu, Yao-Hua Liu, Meng-Chi Yen, Po-Lin Kuo
Publikováno v:
Diagnostics, Vol 10, Iss 4, p 228 (2020)
The survival rate in patients with metastatic renal cell carcinoma (RCC) is low. In addition, metastatic RCC resists traditional treatment. Therefore, identification of novel biomarkers, signaling pathways, and therapeutic targets is an important iss
Externí odkaz:
https://doaj.org/article/d0680767405a4026baf3ecdae0413902
Autor:
Szu-Chia Chen, Mei-Yueh Lee, Jiun-Chi Huang, Hsiu-Chin Mai, Po-Lin Kuo, Jer-Ming Chang, Hung-Chun Chen, Yi-Hsin Yang
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175363 (2017)
Peripheral artery occlusive disease is common among diabetes mellitus (DM) and end-stage renal disease patients, and tends to progress faster and lead to worse outcomes. This study compared the association of DM with the decline in ankle-brachial ind
Externí odkaz:
https://doaj.org/article/25094a966a7b4b6aa2eac16eb8369741
Publikováno v:
Medicina, Vol 55, Iss 9, p 589 (2019)
Background and Objectives: Atropine is a nonselective muscarinic antagonist which has been used to prevent worsening of myopia in children. Different concentrations of atropine were used for myopia, ranging from 0.01% to 1.0%. However, there are stil
Externí odkaz:
https://doaj.org/article/aa5741706667432bad2fe027f0cf21dd
Autor:
Chia-Chun Tseng, Ling-Yu Wu, Wen-Chan Tsai, Tsan-Teng Ou, Cheng-Chin Wu, Wan-Yu Sung, Po-Lin Kuo, Jeng-Hsien Yen
Publikováno v:
Diagnostics, Vol 9, Iss 3, p 98 (2019)
Using next-generation sequencing to decipher the molecular mechanisms underlying aberrant rheumatoid arthritis synovial fibroblasts (RASF) activation, we performed transcriptome-wide RNA-seq and small RNA-seq on synovial fibroblasts from rheumatoid a
Externí odkaz:
https://doaj.org/article/dc115a5856ad4a8f94934b0ce33197b1
Publikováno v:
Diagnostics, Vol 9, Iss 2, p 59 (2019)
Major histocompatibility complex (MHC) class II molecules, encoded by human leukocyte antigen (HLA) class II genes, play important roles in antigen presentation and initiation of immune responses. However, the correlation between HLA class II gene ex
Externí odkaz:
https://doaj.org/article/4019e2fc708a47c190384ed9f66731ee
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Indoleamine 2,3-dioxygenase (IDO) is a rate limiting enzyme in tryptophan-degrading pathways and IDO activity results in immune suppression. Targeting IDO is a strategy of cancer immunotherapies. Our previous studies demonstrate that delivery of shor
Externí odkaz:
https://doaj.org/article/d5b5461335784d9bb63db5d4c3be1b4a