Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Po-Hsun Hou"'
Autor:
Geng‐Ruei Chang, Po‐Hsun Hou, Chao‐Min Wang, Ching‐Feng Wu, Huang‐Kai Su, Huei‐Jyuan Liao, To‐Pang Chen
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract Everolimus, which inhibits mTOR kinase activity and is clinically used in graft rejection treatment, may have a two‐sided influence on metabolic syndrome; its role in obesity and hyperglycemic in animals and humans, however, has been explo
Externí odkaz:
https://doaj.org/article/7e8e4e4ef35d44a5a360a968c1f7e810
Autor:
Po-Hsun Hou, Geng-Ruei Chang, Chin-Pin Chen, Yen-Ling Lin, I-Shuan Chao, Ting-Ting Shen, Frank Mao
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 21, Iss 5, Pp 495-501 (2018)
Objective(s): Weight gain and metabolic disturbances such as dyslipidemia, are frequent side effects of second-generation antipsychotics, including olanzapine. This study examined the metabolic effects of chronic olanzapine exposure. In addition, we
Externí odkaz:
https://doaj.org/article/49ed53d4510f4ce59d68bd4954704d20
Autor:
Geng-Ruei Chang, Po-Hsun Hou, Chao-Min Wang, Jen-Wei Lin, Wei-Li Lin, Tzu-Chun Lin, Huei-Jyuan Liao, Chee-Hong Chan, Yu-Chen Wang
Publikováno v:
Veterinary Sciences, Vol 8, Iss 9, p 189 (2021)
Imipramine is a tricyclic antidepressant that has been approved for treating depression and anxiety in patients and animals and that has relatively mild side effects. However, the mechanisms of imipramine-associated disruption to metabolism and negat
Externí odkaz:
https://doaj.org/article/7f7dc589f9324ebbb7512113f5d508b5
Autor:
Geng-Ruei Chang, Hsien-Yueh Liu, Wei-Cheng Yang, Chao-Min Wang, Ching-Fen Wu, Jen-Wei Lin, Wei-Li Lin, Yu-Chen Wang, Tzu-Chun Lin, Huei-Jyuan Liao, Po-Hsun Hou, Chee-Hong Chan, Chuen-Fu Lin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6680 (2021)
Clozapine is widely employed in the treatment of schizophrenia. Compared with that of atypical first-generation antipsychotics, atypical second-generation antipsychotics such as clozapine have less severe side effects and may positively affect obesit
Externí odkaz:
https://doaj.org/article/8141a4a760e84443989387e4ce94ddcb
Autor:
Ching-Feng Wu, Ching-Yang Wu, Robin Y.-Y. Chiou, Wei-Cheng Yang, Chuen-Fu Lin, Chao-Min Wang, Po-Hsun Hou, Tzu-Chun Lin, Chan-Yen Kuo, Geng-Ruei Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4562 (2021)
Zotarolimus is a semi-synthetic derivative of rapamycin and a novel immunosuppressive agent used to prevent graft rejection. The pharmacological pathway of zotarolimus restricts the kinase activity of the mammalian target of rapamycin (mTOR), which p
Externí odkaz:
https://doaj.org/article/76b9ca090b7b47a9a9e2101e69bcb45d
Autor:
Geng-Ruei Chang, Po-Hsun Hou, Wei-Cheng Yang, Chao-Min Wang, Pei-Shan Fan, Huei-Jyuan Liao, To-Pang Chen
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 267 (2021)
Doxepin is commonly prescribed for depression and anxiety treatment. Doxepin-related disruptions to metabolism and renal/hepatic adverse effects remain unclear; thus, the underlying mechanism of action warrants further research. Here, we investigated
Externí odkaz:
https://doaj.org/article/fb022dace328450bb2a84341d9c927cb
Autor:
Hsiao-Pei Tsai, Po-Hsun Hou, Frank-Chiahung Mao, Chia-Chia Chang, Wei-Cheng Yang, Ching-Feng Wu, Huei-Jyuan Liao, Tzu-Chun Lin, Lan-Szu Chou, Li-Wei Hsiao, Geng-Ruei Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 409 (2021)
Risperidone, a second-generation antipsychotic drug used for schizophrenia treatment with less-severe side effects, has recently been applied in major depressive disorder treatment. The mechanism underlying risperidone-associated metabolic disturbanc
Externí odkaz:
https://doaj.org/article/fa0459d8d1d14275a750ff205c8703ca
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 18, Iss 11, Pp 1063-1071 (2015)
Objective(s):Resveratrol (RES) is a polyphenol compound that has been shown a promising cardioprotective effect. However, some reports have yielded conflicting findings. Herein, we investigated the anti-atherosclerotic effects of RES in apolipoprotei
Externí odkaz:
https://doaj.org/article/f5e00fcae2a84b6f9f1b727df469afdf
Mirtazapine Reduces Adipocyte Hypertrophy and Increases Glucose Transporter Expression in Obese Mice
Autor:
Ching-Feng Wu, Po-Hsun Hou, Frank Chiahung Mao, Yao-Chi Su, Ching-Yang Wu, Wei-Cheng Yang, Chen-Si Lin, Hsiao-Pei Tsai, Huei-Jyuan Liao, Geng-Ruei Chang
Publikováno v:
Animals, Vol 10, Iss 8, p 1423 (2020)
Metabolic syndrome is known to engender type 2 diabetes as well as some cardiac, cerebrovascular, and kidney diseases. Mirtazapine—an atypical second-generation antipsychotic drug with less severe side effects than atypical first-generation antipsy
Externí odkaz:
https://doaj.org/article/2756d097e6394f6190b46596c01ae5e8
Autor:
Geng-Ruei Chang, Po-Hsun Hou, Wen-Kai Chen, Chien-Teng Lin, Hsiao-Pei Tsai, Frank Chiahung Mao
Publikováno v:
Molecules, Vol 25, Iss 7, p 1658 (2020)
Obesity is commonly associated with hyperglycemia and type 2 diabetes and negatively affects chromium accumulation in tissues. Exercise prevents and controls obesity and type 2 diabetes. However, little information is available regarding chromium cha
Externí odkaz:
https://doaj.org/article/18c6708bef2a47d99f9be1af8eb97210