Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Po Yuan Ke"'
Autor:
Chih-Ching Wu, Ee-Hong Tam, Yu-Yin Shih, Yi-Ru Lin, Pei-Chun Hsueh, Hsiang-Yi Shen, Chian-Huey Woung, Li-Ting Wang, Jia-Chen Tsai, Syh-Jae Lin, Chuang-Rung Chang, Po-Yuan Ke, Rei-Lin Kuo
Publikováno v:
Virus Research, Vol 345, Iss , Pp 199387- (2024)
Influenza A virus can infect respiratory tracts and may cause severe illness in humans. Proteins encoded by influenza A virus can interact with cellular factors and dysregulate host biological processes to support viral replication and cause pathogen
Externí odkaz:
https://doaj.org/article/9ba0d038687f4a3197b3bec5b9583a5e
Autor:
Po-Yuan Ke
Publikováno v:
Cells, Vol 13, Iss 6, p 500 (2024)
In eukaryotes, targeting intracellular components for lysosomal degradation by autophagy represents a catabolic process that evolutionarily regulates cellular homeostasis. The successful completion of autophagy initiates the engulfment of cytoplasmic
Externí odkaz:
https://doaj.org/article/a394f9ca6c204c218136d7d6e704fab8
Autor:
Po-Yuan Ke
Publikováno v:
Pathogens, Vol 13, Iss 3, p 266 (2024)
Autophagy plays a fundamental role in maintaining cellular homeostasis by eliminating intracellular components via lysosomes. Successful degradation through autophagy relies on the fusion of autophagosomes to lysosomes, which leads to the formation o
Externí odkaz:
https://doaj.org/article/c2357872e42e487ab6da85a4da9e8916
Autor:
Po-Yuan Ke
Publikováno v:
Cells, Vol 12, Iss 6, p 956 (2023)
Autophagy plays a homeostatic role in regulating cellular metabolism by degrading unwanted intracellular materials and acts as a host defense mechanism by eliminating infecting pathogens, such as viruses. Upon viral infection, host cells often activa
Externí odkaz:
https://doaj.org/article/d50aa3c4133c456e99e2a2e35bcf64b4
Autor:
Ming-Wei Lai, Yu-De Chu, Chih-Lang Lin, Rong-Nan Chien, Ta-Sen Yeh, Tai-Long Pan, Po-Yuan Ke, Kwang-Hui Lin, Chau-Ting Yeh
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Although men carry a higher risk of hepatocellular carcinoma (HCC) than women, it is still controversial whether men also have a poorer postoperative prognosis. A retrospective study was conducted to evaluate the postoperative pro
Externí odkaz:
https://doaj.org/article/62f2105a944841adaac270631c2c246e
Publikováno v:
Cells, Vol 11, Iss 7, p 1132 (2022)
The elimination of intracellular components by autophagy maintains metabolic homeostasis and is a quality-control pathway that enables organelle regeneration. Mitophagy is a type of selective autophagy that regulates mitochondrial turnover, and the d
Externí odkaz:
https://doaj.org/article/cdf3c6bc2625454398496b6e63c5285d
Autor:
Ya-Hui Huang, Kung-Hao Liang, Rong-Nan Chien, Tsung-Hui Hu, Kwang-Huei Lin, Chao-Wei Hsu, Chih-Lang Lin, Tai-Long Pan, Po-Yuan Ke, Chau-Ting Yeh
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract With the availability of potent antiviral therapies, complete suppression of hepatitis B virus (HBV) replication and total eradication of hepatitis C virus (HCV) can now be achieved. Despite these advances, hepatocellular carcinoma (HCC) sti
Externí odkaz:
https://doaj.org/article/681de4d9890645de85abd9bbc8cfa40f
Autor:
Po-Yuan Ke
Publikováno v:
Biomedical Journal, Vol 40, Iss 1, Pp 5-8 (2017)
Autophagy is an evolutionarily conserved process by which eukaryotic cells eliminate intracellular components via the lysosomal degradation process. This cell self-digestion process was first discovered and morphologically characterized in the late 1
Externí odkaz:
https://doaj.org/article/38ffee984fa941b9a131b208bdc4bdf3
Autor:
Po-Yuan Ke
Publikováno v:
IUBMB Life. 74:317-338
Targeting intracellular components for lysosomal degradation by autophagy not only maintains cellular homeostasis but also counteracts the effects of external stimuli, including invading pathogens. Among various kinds of pathogens, viruses have been
Autor:
Po-Yuan Ke
Publikováno v:
Cells, Vol 9, Iss 4, p 831 (2020)
Autophagy is a catabolic process involving vacuolar sequestration of intracellular components and their targeting to lysosomes for degradation, thus supporting nutrient recycling and energy regeneration. Accumulating evidence indicates that in additi
Externí odkaz:
https://doaj.org/article/8e41cdc4a6ed4f58b7d90cea8834cf4c