Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Po Ming Chen"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Human metallothionein-2A (MT2A) protein participates in metal homeostasis, detoxification, oxidative stress reduction, and immune defense. It decreases heavy metal ions and reactive oxygen species (ROS) during injury of cells and tissues. Th
Externí odkaz:
https://doaj.org/article/df77f35408634b12b34f2d222c49d5d1
Autor:
Sheng-Chieh Lin, Yi-Chu Liao, Po-Ming Chen, Ya-Yu Yang, Yi-Hsiang Wang, Shiao-Lin Tung, Chi-Mu Chuang, Yu-Wen Sung, Te-Hsuan Jang, Shuang-En Chuang, Lu-Hai Wang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-17 (2022)
Abstract Background Ovarian cancer has the highest mortality among gynecological cancers due to late diagnosis and lack of effective targeted therapy. Although the study of interplay between cancer cells with their microenvironment is emerging, how o
Externí odkaz:
https://doaj.org/article/4091e35327aa44ed87ac21be9b28eec1
Autor:
Te-Hsuan Jang, Wei-Chieh Huang, Shiao-Lin Tung, Sheng-Chieh Lin, Po-Ming Chen, Chun-Yu Cho, Ya-Yu Yang, Tzu-Chen Yen, Guo-Hsuen Lo, Shuang-En Chuang, Lu-Hai Wang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)
Abstract Background The development of drug resistance in oral squamous cell carcinoma (OSCC) that frequently leads to recurrence and metastasis after initial treatment remains an unresolved challenge. Presence of cancer stem cells (CSCs) has been in
Externí odkaz:
https://doaj.org/article/270a545c232249de8d6a0e4c5b53f5f3
Autor:
Sheng-Chieh Lin, Yi-Chu Liao, Po-Ming Chen, Ya-Yu Yang, Yi-Hsiang Wang, Shiao-Lin Tung, Chi-Mu Chuang, Yu-Wen Sung, Te-Hsuan Jang, Shuang-En Chuang, Lu-Hai Wang
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/daa8464071024502883d4e19dfea9507
Publikováno v:
Cells, Vol 12, Iss 12, p 1641 (2023)
Serum and glucocorticoid-regulated kinase 1 (SGK1) is expressed in neuronal cells and involved in the pathogenesis of hypertension and metabolic syndrome, regulation of neuronal function, and depression in the brain. This study aims to identify the c
Externí odkaz:
https://doaj.org/article/9675b117dda24ae59fac72f61d17f010
Publikováno v:
Thoracic Cancer, Vol 12, Iss 4, Pp 534-538 (2021)
Abstract Background The human 8‐oxoguanine DNA glycosylase 1 (hOGG1) gene encodes a DNA glycosylase that removes 8‐hydroxy‐2‐deoxyguanine (8‐OH‐dG) DNA damage to protect against gene mutations. The association of hOGG1 Ser326Cys polymorph
Externí odkaz:
https://doaj.org/article/661cc5137eb647efa95ad67552f63e50
Publikováno v:
Cancer Informatics, Vol 19 (2020)
RNA-Sequencing (RNA-Seq), the most commonly used sequencing application tool, is not only a method for measuring gene expression but also an excellent media to detect important structural variants such as single nucleotide variants (SNVs), insertion/
Externí odkaz:
https://doaj.org/article/a91c6d23e0fc45b49eda586de6a427fc
Autor:
Chun-Wen Cheng, Jyh-Cherng Yu, Yi-Hsien Hsieh, Wen-Ling Liao, Jia-Ching Shieh, Chung-Chin Yao, Huei-Jane Lee, Po-Ming Chen, Pei-Ei Wu, Chen-Yang Shen
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 5, Pp 2205-2218 (2018)
Background /Aims: Recent studies of microRNA (miRNA) involvement in tumorigenesis have indicated the critical role of these non-coding small RNAs in malignant transformation, but the prognostic role, if any, of miRNAs in breast cancer remains undeter
Externí odkaz:
https://doaj.org/article/8f92b1caff4e4672928fa9c831d5d613
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. The disease recurrent rate is relatively high resulted in poor 5-year survival in advanced HCC. Cancer stem cells (CSCs) have been consi
Externí odkaz:
https://doaj.org/article/bbe5d679c8c2422288b55f07ded65ded
Autor:
Wei-Chieh Huang, Hsiang-Cheng Chi, Shiao-Lin Tung, Po-Ming Chen, Ya-Chi Shih, Yi-Ching Huang, Pei-Yi Chu
Publikováno v:
Cells, Vol 10, Iss 10, p 2524 (2021)
Triple negative breast cancer (TNBC) possesses poor prognosis mainly due to development of chemoresistance and lack of effective endocrine or targeted therapies. MiR-491-5p has been found to play a tumor suppressor role in many cancers including brea
Externí odkaz:
https://doaj.org/article/01a4edd024ca421cad755f14f0de0a79